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Aliases for MIR638 Gene

Subcategory (RNA class) for MIR638 Gene


Quality Score for this RNA gene is


Aliases for MIR638 Gene

  • MicroRNA 638 2 3
  • Hsa-Mir-638 3
  • MIRN638 3

External Ids for MIR638 Gene

ORGUL Members for MIR638 Gene

Previous HGNC Symbols for MIR638 Gene

  • MIRN638

Previous GeneCards Identifiers for MIR638 Gene

  • GC19U901002
  • GC19P010829

Summaries for MIR638 Gene

Entrez Gene Summary for MIR638 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR638 Gene

MIR638 (MicroRNA 638) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR638 Gene

Genomics for MIR638 Gene

Genomic Location for MIR638 Gene

10,718,404 bp from pter
10,718,503 bp from pter
100 bases
Plus strand

Genomic View for MIR638 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR638 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR638 Gene

No data available for Regulatory Elements for MIR638 Gene

Proteins for MIR638 Gene

Post-translational modifications for MIR638 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR638 Gene

Domains & Families for MIR638 Gene

Gene Families for MIR638 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR638: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR638 Gene

Function for MIR638 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR638 Gene

Localization for MIR638 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR638 Gene

Pathways & Interactions for MIR638 Gene

SuperPathways for MIR638 Gene

No Data Available

Interacting Proteins for MIR638 Gene

Gene Ontology (GO) - Biological Process for MIR638 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR638 Gene

Drugs & Compounds for MIR638 Gene

No Compound Related Data Available

Transcripts for MIR638 Gene

mRNA/cDNA for MIR638 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR638 Gene

No ASD Table

Relevant External Links for MIR638 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR638 Gene

mRNA expression in normal human tissues for MIR638 Gene

genes like me logo Genes that share expression patterns with MIR638: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR638 Gene

Orthologs for MIR638 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR638 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
Species with no ortholog for MIR638:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR638 Gene

Gene Tree for MIR638 (if available)
Gene Tree for MIR638 (if available)

Paralogs for MIR638 Gene

No data available for Paralogs for MIR638 Gene

Variants for MIR638 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR638 Gene

Variant ID Type Subtype PubMed ID
nsv833745 CNV Loss 17160897
nsv911047 CNV Loss 21882294
nsv833746 CNV Loss 17160897

Relevant External Links for MIR638 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR638 Gene

Disorders for MIR638 Gene

Relevant External Links for MIR638

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR638: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR638 Gene

Publications for MIR638 Gene

  1. miR-638 regulates differentiation and proliferation in leukemic cells by targeting cyclin-dependent kinase 2. (PMID: 25451924) Lin Y. … Huang Z. (J. Biol. Chem. 2015) 67
  2. Secretion of small/microRNAs including miR-638 into extracellular spaces by sphingomyelin phosphodiesterase 3. (PMID: 25394686) Kubota S. … Watanabe N. (Oncol. Rep. 2015) 67
  3. Characterization of dual PTEN and p53-targeting microRNAs identifies microRNA-638/Dnm2 as a two-hit oncogenic locus. (PMID: 25088422) Tay Y. … Pandolfi P.P. (Cell Rep 2014) 67
  4. miR-638 suppresses cell proliferation in gastric cancer by targeting Sp2. (PMID: 24623314) Zhao L.Y. … Shao Y. (Dig. Dis. Sci. 2014) 67
  5. Downregulation of miR-638 promotes invasion and proliferation by regulating SOX2 and induces EMT in NSCLC. (PMID: 24842609) Xia Y. … Chen Y. (FEBS Lett. 2014) 67

Products for MIR638 Gene

Sources for MIR638 Gene

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