Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR637 Gene

Subcategory (RNA class) for MIR637 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR637 Gene

  • MicroRNA 637 2 3
  • Hsa-Mir-637 3
  • MIRN637 3

External Ids for MIR637 Gene

Previous HGNC Symbols for MIR637 Gene

  • MIRN637

Previous GeneCards Identifiers for MIR637 Gene

  • GC19M003913

Summaries for MIR637 Gene

Entrez Gene Summary for MIR637 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR637 Gene

MIR637 (MicroRNA 637) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR637 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR637

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR637 Gene

Genomics for MIR637 Gene

Genomic Location for MIR637 Gene

Chromosome:
19
Start:
3,961,414 bp from pter
End:
3,961,512 bp from pter
Size:
99 bases
Orientation:
Minus strand

Genomic View for MIR637 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR637 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR637 Gene

ORGUL Member Location for MIR637 Gene

ORGUL Member Location for MIR637 gene

No data available for Regulatory Elements for MIR637 Gene

Proteins for MIR637 Gene

Post-translational modifications for MIR637 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR637 Gene

Domains & Families for MIR637 Gene

Gene Families for MIR637 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR637: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR637 Gene

Function for MIR637 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR637 Gene

Localization for MIR637 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR637 Gene

Pathways & Interactions for MIR637 Gene

SuperPathways for MIR637 Gene

No Data Available

Interacting Proteins for MIR637 Gene

Gene Ontology (GO) - Biological Process for MIR637 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR637 Gene

Drugs & Compounds for MIR637 Gene

No Compound Related Data Available

Transcripts for MIR637 Gene

fRNAdb Secondary structures for MIR637 Gene

  • hsa-mir-637_MI0003652_Homo_sapiens_miR-637_stem-loop_hairpin

mRNA/cDNA for MIR637 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR637 Gene

No ASD Table

Relevant External Links for MIR637 Gene

GeneLoc Exon Structure for
MIR637
ECgene alternative splicing isoforms for
MIR637

Expression for MIR637 Gene

mRNA expression in normal human tissues for MIR637 Gene

genes like me logo Genes that share expression patterns with MIR637: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR637 Gene

Orthologs for MIR637 Gene

Evolution for MIR637 Gene

ENSEMBL:
Gene Tree for MIR637 (if available)
TreeFam:
Gene Tree for MIR637 (if available)

No data available for Orthologs for MIR637 Gene

Paralogs for MIR637 Gene

No data available for Paralogs for MIR637 Gene

Variants for MIR637 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR637 Gene

Variant ID Type Subtype PubMed ID
nsv833715 CNV Loss 17160897
nsv910780 CNV Loss 21882294
dgv3665n71 CNV Loss 21882294
nsv910783 CNV Loss 21882294
nsv910786 CNV Loss 21882294
dgv3666n71 CNV Loss 21882294
nsv910791 CNV Loss 21882294

Relevant External Links for MIR637 Gene

HapMap Linkage Disequilibrium report
MIR637

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR637 Gene

Disorders for MIR637 Gene

Relevant External Links for MIR637

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR637
genes like me logo Genes that share disorders with MIR637: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR637 Gene

Publications for MIR637 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 67
  2. Vitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts. (PMID: 23362149) Lisse T.S. … Hewison M. (J. Bone Miner. Res. 2013) 67
  3. Primate-specific microRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling. (PMID: 21809363) Zhang J.F. … Kung H.F. (Hepatology 2011) 67
  4. MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix. (PMID: 21880893) Zhang J.F. … Kung H.F. (Mol. Biol. Cell 2011) 67
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR637 Gene

Sources for MIR637 Gene

Back to Top

Content