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Aliases for MIR629 Gene

Subcategory (RNA class) for MIR629 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR629 Gene

  • MicroRNA 629 2 3
  • Hsa-Mir-629 3
  • MIRN629 3

External Ids for MIR629 Gene

Previous Symbols for MIR629 Gene

  • MIRN629

Summaries for MIR629 Gene

Entrez Gene Summary for MIR629 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR629 Gene

MIR629 (MicroRNA 629) is a RNA Gene, and belongs to miRNA RNA class.

fRNAdb sequence ontologies for MIR629 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR629

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR629 Gene

Genomics for MIR629 Gene

Genomic Location for MIR629 Gene

Start:
70,079,372 bp from pter
End:
70,079,468 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR629 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR629 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR629 Gene

ORGUL Member Location for MIR629 Gene

ORGUL Member Location for MIR629 gene

No data available for Regulatory Elements for MIR629 Gene

Proteins for MIR629 Gene

Post-translational modifications for MIR629 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR629 Gene

Domains for MIR629 Gene

Gene Families for MIR629 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR629: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR629 Gene

Function for MIR629 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR629 Gene

Localization for MIR629 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR629 Gene

Pathways for MIR629 Gene

SuperPathways for MIR629 Gene

No Data Available

Interacting Proteins for MIR629 Gene

Gene Ontology (GO) - Biological Process for MIR629 Gene

None

No data available for Pathways by source for MIR629 Gene

Transcripts for MIR629 Gene

fRNAdb Secondary structures for MIR629 Gene

  • hsa-mir-629_MI0003643_Homo_sapiens_miR-629_stem-loop_hairpin

mRNA/cDNA for MIR629 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR629 Gene

No ASD Table

Relevant External Links for MIR629 Gene

GeneLoc Exon Structure for
MIR629
ECgene alternative splicing isoforms for
MIR629

Expression for MIR629 Gene

mRNA expression in normal human tissues for MIR629 Gene

genes like me logo Genes that share expressions with MIR629: view

Orthologs for MIR629 Gene

Evolution for MIR629 Gene

ENSEMBL:
Gene Tree for MIR629 (if available)
TreeFam:
Gene Tree for MIR629 (if available)

No data available for Orthologs for MIR629 Gene

Paralogs for MIR629 Gene

No data available for Paralogs for MIR629 Gene

Variants for MIR629 Gene

Relevant External Links for MIR629 Gene

HapMap Linkage Disequilibrium report
MIR629

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR629 Gene

Disorders for MIR629 Gene

No disorders were found for MIR629 Gene.

No data available for UniProtKB/Swiss-Prot for MIR629 Gene

Publications for MIR629 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. A functional polymorphism at microRNA-629-binding site in the 3'-untranslated region of NBS1 gene confers an increased risk of lung cancer in Southern and Eastern Chinese population. (PMID: 22114071) Yang L. … Lu J. (Carcinogenesis 2012) 3
  5. High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus. (PMID: 24687380) Zhu J. … Song G. (Clin. Rheumatol. 2014) 3

Products for MIR629 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR629
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR629
    • Block miRNA regulation of MIR629 using miScript Target Protectors

    Sources for MIR629 Gene

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