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Aliases for MIR629 Gene

Subcategory (RNA class) for MIR629 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR629 Gene

  • MicroRNA 629 2 3 5
  • Hsa-Mir-629 3
  • Mir-629 3
  • MIRN629 3

External Ids for MIR629 Gene

Previous HGNC Symbols for MIR629 Gene

  • MIRN629

Previous GeneCards Identifiers for MIR629 Gene

  • GC15M068159
  • GC15M070371

Summaries for MIR629 Gene

Entrez Gene Summary for MIR629 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR629 Gene

MIR629 (MicroRNA 629) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR629 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR629

Additional gene information for MIR629 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR629 Gene

Genomics for MIR629 Gene

Regulatory Elements for MIR629 Gene

Enhancers for MIR629 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15H070503 2 FANTOM5 Ensembl ENCODE dbSUPER 10.5 -427.3 -427269 7 PKNOX1 FOXA2 SIN3A FEZF1 ZNF2 ZNF416 ZNF143 FOS DEK SP3 TLE3 RPL17P39 MIR629 LINC02205 PIR55212
GH15H070491 2 FANTOM5 Ensembl ENCODE dbSUPER 10.3 -414.4 -414382 5 HDGF PKNOX1 SIN3A FEZF1 ZNF2 ZNF766 ZNF416 FOS SP3 REST TLE3 LRRC49 RPL17P39 THAP10 MIR629 LINC02205 PIR51135
GH15H070478 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.7 -400.2 -400205 2 PKNOX1 TBL1XR1 ZNF493 BATF ZNF143 RCOR1 ETV6 RUNX3 CREM IKZF2 TLE3 RPL17P39 MIR629 PIR51135 LINC02205
GH15H070139 1.7 FANTOM5 Ensembl ENCODE 10.5 -62.7 -62708 4 PKNOX1 FOXA2 ATF1 MLX ZFP64 ARID4B TCF12 SLC30A9 ZNF143 FOS TLE3 ENSG00000259744 MIR629 LARP6 GC15P070099 GC15P070194
GH15H070486 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.2 -407.8 -407766 2 HDGF TBL1XR1 KLF17 SIN3A BMI1 BATF ZNF2 RAD21 RFX5 ZNF121 TLE3 MIR629 PIR51135 LINC02205
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR629 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR629 Gene

Chromosome:
15
Start:
70,079,372 bp from pter
End:
70,079,468 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR629 Gene

Genes around MIR629 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR629 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR629 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR629 Gene

ORGUL Member Location for MIR629 Gene

ORGUL Member Location for MIR629 gene

Proteins for MIR629 Gene

Post-translational modifications for MIR629 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR629 Gene

Domains & Families for MIR629 Gene

Gene Families for MIR629 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR629: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR629 Gene

Function for MIR629 Gene

Phenotypes From GWAS Catalog for MIR629 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR629
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR629 Gene

Localization for MIR629 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR629 Gene

Pathways & Interactions for MIR629 Gene

SuperPathways for MIR629 Gene

No Data Available

Interacting Proteins for MIR629 Gene

Gene Ontology (GO) - Biological Process for MIR629 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR629 Gene

Drugs & Compounds for MIR629 Gene

No Compound Related Data Available

Transcripts for MIR629 Gene

fRNAdb Secondary structures for MIR629 Gene

  • hsa-mir-629_MI0003643_Homo_sapiens_miR-629_stem-loop_hairpin

mRNA/cDNA for MIR629 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR629
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR629 Gene

No ASD Table

Relevant External Links for MIR629 Gene

GeneLoc Exon Structure for
MIR629
ECgene alternative splicing isoforms for
MIR629

Expression for MIR629 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR629 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR629 Gene:

MIR629
genes like me logo Genes that share expression patterns with MIR629: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR629 Gene

Orthologs for MIR629 Gene

Evolution for MIR629 Gene

ENSEMBL:
Gene Tree for MIR629 (if available)
TreeFam:
Gene Tree for MIR629 (if available)

No data available for Orthologs for MIR629 Gene

Paralogs for MIR629 Gene

No data available for Paralogs for MIR629 Gene

Variants for MIR629 Gene

Sequence variations from dbSNP and Humsavar for MIR629 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000639417 -- 70,079,619(+) TGCAC(G/T)CTGCA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1000982866 -- 70,080,252(+) CACTG(C/G)TTTTG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1001913818 -- 70,080,654(+) CATTT(C/G)CATGA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1005424144 -- 70,078,945(+) AAAGA(A/T)ACGTA intron-variant, downstream-variant-500B
rs1005524410 -- 70,081,318(+) CATCA(C/T)ATGAA intron-variant, nc-transcript-variant, upstream-variant-2KB

Relevant External Links for MIR629 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR629

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR629 Gene

Disorders for MIR629 Gene

Relevant External Links for MIR629

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR629

No disorders were found for MIR629 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR629 Gene

Publications for MIR629 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 1 3 60
  2. Asthma inflammatory phenotypes show differential microRNA expression in sputum. (PMID: 27155035) Maes T … Louis R (The Journal of allergy and clinical immunology 2016) 3 60
  3. miR-629 Targets TRIM33 to Promote TGFβ/Smad Signaling and Metastatic Phenotypes in ccRCC. (PMID: 25381221) Jingushi K … Tsujikawa K (Molecular cancer research : MCR 2015) 3 60
  4. High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus. (PMID: 24687380) Zhu J … Song G (Clinical rheumatology 2014) 3 60
  5. A functional polymorphism at microRNA-629-binding site in the 3'-untranslated region of NBS1 gene confers an increased risk of lung cancer in Southern and Eastern Chinese population. (PMID: 22114071) Yang L … Lu J (Carcinogenesis 2012) 3 60

Products for MIR629 Gene

Sources for MIR629 Gene

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