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Aliases for MIR629 Gene

Subcategory (RNA class) for MIR629 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR629 Gene

  • MicroRNA 629 2 3 5
  • Hsa-Mir-629 3
  • Mir-629 3
  • MIRN629 3

External Ids for MIR629 Gene

Previous HGNC Symbols for MIR629 Gene

  • MIRN629

Previous GeneCards Identifiers for MIR629 Gene

  • GC15M068159
  • GC15M070371

Summaries for MIR629 Gene

Entrez Gene Summary for MIR629 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR629 Gene

MIR629 (MicroRNA 629) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR629 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR629

Additional gene information for MIR629 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR629 Gene

Genomics for MIR629 Gene

GeneHancer (GH) Regulatory Elements for MIR629 Gene

Promoters and enhancers for MIR629 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I070078 Enhancer 0.9 ENCODE 550.8 +0.3 260 2.3 FOXA2 MLX ARID4B DMAP1 ZNF48 YY1 RXRA SP5 NFYC ZHX2 MIR629 LOC105370877 TLE3 LOC101929129
GH15I070503 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 10.5 -427.3 -427268 7.1 PKNOX1 CLOCK FOXA2 SMAD1 NEUROD1 SIN3A FEZF1 ZNF2 E2F8 ZNF416 LINC02205 TLE3 RPL17P39 MIR629 PIR55212 GC15M070491
GH15I070491 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.3 -414.4 -414382 5.6 HDGF PKNOX1 NEUROD1 SIN3A FEZF1 ZNF2 ZNF766 ZNF213 ZNF416 FOS LRRC49 TLE3 THAP10 RPL17P39 MIR629 LINC02205 PIR51135 GC15M070491
GH15I070194 Enhancer 1.5 Ensembl ENCODE dbSUPER 10.8 -118.2 -118232 6.2 HDGF PKNOX1 FOXA2 NEUROD1 SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1 ENSG00000259252 TLE3 MIR629 RNU6-745P GC15M070188
GH15I070478 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 10.7 -400.2 -400204 2.5 PKNOX1 ZNF493 BATF IRF4 ZNF143 RCOR1 ETV6 IKZF2 RUNX3 EGR2 TLE3 RPL17P39 MIR629 PIR51135 LINC02205
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR629 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR629 Gene

Genomic Locations for MIR629 Gene
chr15:70,079,372-70,079,468
(GRCh38/hg38)
Size:
97 bases
Orientation:
Minus strand
chr15:70,371,711-70,371,807
(GRCh37/hg19)

Genomic View for MIR629 Gene

Genes around MIR629 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR629 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR629 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR629 Gene

ORGUL Member Location for MIR629 Gene

ORGUL Member Location for MIR629 gene

Proteins for MIR629 Gene

Post-translational modifications for MIR629 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR629 Gene

Domains & Families for MIR629 Gene

Gene Families for MIR629 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR629: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR629 Gene

Function for MIR629 Gene

Phenotypes From GWAS Catalog for MIR629 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR629 Gene

Localization for MIR629 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR629 Gene

Pathways & Interactions for MIR629 Gene

SuperPathways for MIR629 Gene

No Data Available

Interacting Proteins for MIR629 Gene

Gene Ontology (GO) - Biological Process for MIR629 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR629 Gene

Drugs & Compounds for MIR629 Gene

No Compound Related Data Available

Transcripts for MIR629 Gene

fRNAdb Secondary structures for MIR629 Gene

  • hsa-mir-629_MI0003643_Homo_sapiens_miR-629_stem-loop_hairpin

mRNA/cDNA for MIR629 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR629 Gene

No ASD Table

Relevant External Links for MIR629 Gene

GeneLoc Exon Structure for
MIR629
ECgene alternative splicing isoforms for
MIR629

Expression for MIR629 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR629 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR629 Gene:

MIR629
genes like me logo Genes that share expression patterns with MIR629: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR629 Gene

Orthologs for MIR629 Gene

Evolution for MIR629 Gene

ENSEMBL:
Gene Tree for MIR629 (if available)
TreeFam:
Gene Tree for MIR629 (if available)

No data available for Orthologs for MIR629 Gene

Paralogs for MIR629 Gene

No data available for Paralogs for MIR629 Gene

Variants for MIR629 Gene

Sequence variations from dbSNP and Humsavar for MIR629 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000639417 -- 70,079,619(-) T/G upstream_transcript_variant
rs1000982866 -- 70,080,252(-) C/G upstream_transcript_variant
rs1001913818 -- 70,080,654(-) G/C upstream_transcript_variant
rs1005424144 -- 70,078,945(-) A/T downstream_transcript_variant
rs1005524410 -- 70,081,318(-) C/T upstream_transcript_variant

Additional Variant Information for MIR629 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR629

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR629 Gene

Disorders for MIR629 Gene

Additional Disease Information for MIR629

No disorders were found for MIR629 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR629 Gene

Publications for MIR629 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 1 3 58
  2. Knockdown of miR-629 Inhibits Ovarian Cancer Malignant Behaviors by Targeting Testis-Specific Y-Like Protein 5. (PMID: 28972400) Shao L … Chen Y (DNA and cell biology 2017) 3 58
  3. Asthma inflammatory phenotypes show differential microRNA expression in sputum. (PMID: 27155035) Maes T … Louis R (The Journal of allergy and clinical immunology 2016) 3 58
  4. miR-629 Targets TRIM33 to Promote TGFβ/Smad Signaling and Metastatic Phenotypes in ccRCC. (PMID: 25381221) Jingushi K … Tsujikawa K (Molecular cancer research : MCR 2015) 3 58
  5. High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus. (PMID: 24687380) Zhu J … Song G (Clinical rheumatology 2014) 3 58

Products for MIR629 Gene

Sources for MIR629 Gene

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