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MIR629 Gene(RNA Gene)

MicroRNA 629

GCID:
GC15M070079
GIFtS:
16
Genes Participants
UDN Logo

Aliases for MIR629 Gene

Subcategory (RNA class) for MIR629 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR629 Gene

  • MicroRNA 629 2 3 5
  • Hsa-Mir-629 3
  • Mir-629 3
  • MIRN629 3

External Ids for MIR629 Gene

ORGUL Members for MIR629 Gene

Previous HGNC Symbols for MIR629 Gene

  • MIRN629

Previous GeneCards Identifiers for MIR629 Gene

  • GC15M068159
  • GC15M070371

Summaries for MIR629 Gene

Entrez Gene Summary for MIR629 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR629 Gene

MIR629 (MicroRNA 629) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR629 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR629

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR629 Gene

Genomics for MIR629 Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR629 Gene

Enhancers for MIR629 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F070139 1.7 FANTOM5 Ensembl ENCODE 10.5 -62.7 -62651 4.6 PKNOX1 ATF1 MLX ZFP64 ARID4B ZNF2 ZNF48 YY1 SLC30A9 ZNF143 TLE3 MIR629 LARP6 ENSG00000259744 GC15P070099 GC15P070194
GH15F070257 1.7 FANTOM5 Ensembl ENCODE 10.5 -185.4 -185433 15.4 PKNOX1 GLI4 FEZF1 ZNF2 BRCA1 ZNF143 ZNF207 FOS DEK ZNF263 LOC105370880 ENSG00000259309 ENSG00000259624 MIR629 TLE3 GC15P070262 GC15P070279
GH15F070501 1.7 FANTOM5 Ensembl ENCODE 10.5 -426.5 -426489 8.7 PKNOX1 WRNIP1 SIN3A FEZF1 ZNF2 YY1 ZNF416 FOS DEK ZNF263 TLE3 MIR629 HMGB1P6 RPL17P39 LOC105370880 PIR51135
GH15F070490 1.7 FANTOM5 Ensembl ENCODE 10.3 -414.1 -414062 6.3 HDGF PKNOX1 ARID4B SIN3A FEZF1 ZNF2 ZNF416 FOS ZNF263 SP3 TLE3 HMGB1P6 MIR629 LOC105370880 PIR51135
GH15F070318 1.7 FANTOM5 Ensembl ENCODE 9.7 -242.4 -242385 7.0 PKNOX1 MLX WRNIP1 ARID4B FEZF1 YY1 SLC30A9 FOS SP5 MXD4 MIR629 ENSG00000259503 GC15M070405
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR629 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR629 Gene

Chromosome:
15
Start:
70,079,372 bp from pter
End:
70,079,468 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR629 Gene

Genes around MIR629 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR629 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR629 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR629 Gene

ORGUL Member Location for MIR629 Gene

ORGUL Member Location for MIR629 gene

Proteins for MIR629 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR629 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR629 Gene

Domains & Families for MIR629 Gene

Gene Families for MIR629 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR629: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR629 Gene

Function for MIR629 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR629 Gene

Localization for MIR629 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR629 Gene

Pathways & Interactions for MIR629 Gene

SuperPathways for MIR629 Gene

PathCards logo More details on SuperPathways for MIR629
No Data Available

Interacting Proteins for MIR629 Gene

Gene Ontology (GO) - Biological Process for MIR629 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR629 Gene

Drugs & Compounds for MIR629 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR629 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

fRNAdb Secondary structures for MIR629 Gene

  • hsa-mir-629_MI0003643_Homo_sapiens_miR-629_stem-loop_hairpin

mRNA/cDNA for MIR629 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR629 Gene

No ASD Table

Relevant External Links for MIR629 Gene

GeneLoc Exon Structure for
MIR629
ECgene alternative splicing isoforms for
MIR629

Expression for MIR629 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR629 Gene

mRNA expression in normal human tissues for MIR629 Gene
mRNA expression by GTEx for MIR629 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR629 Gene:

MIR629
genes like me logo Genes that share expression patterns with MIR629: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR629 Gene

Orthologs for MIR629 Gene

Evolution for MIR629 Gene

ENSEMBL:
Gene Tree for MIR629 (if available)
TreeFam:
Gene Tree for MIR629 (if available)

No data available for Orthologs for MIR629 Gene

Paralogs for MIR629 Gene

No data available for Paralogs for MIR629 Gene

Variants for MIR629 Gene

Sequence variations from dbSNP and Humsavar for MIR629 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs111899904 -- 70,079,433(+) GTTCT(C/T)CCAAC intron-variant, nc-transcript-variant, downstream-variant-500B
rs112964929 -- 70,079,887(+) TTTCA(C/T)TAAAT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs114444095 -- 70,079,211(+) TGAGG(G/T)CTATC intron-variant, downstream-variant-500B
rs115737157 -- 70,080,933(+) CCGTC(A/G)AGAGC intron-variant, nc-transcript-variant, upstream-variant-2KB
rs117102101 -- 70,080,932(+) ACCGT(C/T)GAGAG intron-variant, nc-transcript-variant, upstream-variant-2KB

Relevant External Links for MIR629 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR629

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR629 Gene

Disorders for MIR629 Gene

Relevant External Links for MIR629

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR629

No disorders were found for MIR629 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR629 Gene

Publications for MIR629 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3 64
  2. miR-629 Targets TRIM33 to Promote TGFI^/Smad Signaling and Metastatic Phenotypes in ccRCC. (PMID: 25381221) Jingushi K. … Tsujikawa K. (Mol. Cancer Res. 2015) 3 64
  3. High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus. (PMID: 24687380) Zhu J. … Song G. (Clin. Rheumatol. 2014) 3 64
  4. A functional polymorphism at microRNA-629-binding site in the 3'-untranslated region of NBS1 gene confers an increased risk of lung cancer in Southern and Eastern Chinese population. (PMID: 22114071) Yang L. … Lu J. (Carcinogenesis 2012) 3 64
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64

Products for MIR629 Gene

Sources for MIR629 Gene

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