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Aliases for MIR625 Gene

Subcategory (RNA class) for MIR625 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR625 Gene

  • MicroRNA 625 2 3 5
  • Hsa-Mir-625 3
  • MIRN625 3

External Ids for MIR625 Gene

ORGUL Members for MIR625 Gene

Previous HGNC Symbols for MIR625 Gene

  • MIRN625

Previous GeneCards Identifiers for MIR625 Gene

  • GC14P065008
  • GC14P065937

Summaries for MIR625 Gene

Entrez Gene Summary for MIR625 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR625 Gene

MIR625 (MicroRNA 625) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR625 Gene

Genomics for MIR625 Gene

Genomic Location for MIR625 Gene

Chromosome:
14
Start:
65,471,102 bp from pter
End:
65,471,186 bp from pter
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR625 Gene

Genes around MIR625 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR625 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR625 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR625 Gene

No data available for Regulatory Elements for MIR625 Gene

Proteins for MIR625 Gene

Post-translational modifications for MIR625 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR625 Gene

Domains & Families for MIR625 Gene

Gene Families for MIR625 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR625: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR625 Gene

Function for MIR625 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR625 Gene

Localization for MIR625 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR625 Gene

Pathways & Interactions for MIR625 Gene

SuperPathways for MIR625 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR625: view

Pathways by source for MIR625 Gene

1 KEGG pathway for MIR625 Gene

Interacting Proteins for MIR625 Gene

Gene Ontology (GO) - Biological Process for MIR625 Gene

None

No data available for SIGNOR curated interactions for MIR625 Gene

Drugs & Compounds for MIR625 Gene

No Compound Related Data Available

Transcripts for MIR625 Gene

mRNA/cDNA for MIR625 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR625 Gene

No ASD Table

Relevant External Links for MIR625 Gene

GeneLoc Exon Structure for
MIR625
ECgene alternative splicing isoforms for
MIR625

Expression for MIR625 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR625 Gene

Orthologs for MIR625 Gene

Evolution for MIR625 Gene

ENSEMBL:
Gene Tree for MIR625 (if available)
TreeFam:
Gene Tree for MIR625 (if available)

No data available for Orthologs for MIR625 Gene

Paralogs for MIR625 Gene

No data available for Paralogs for MIR625 Gene

Variants for MIR625 Gene

Relevant External Links for MIR625 Gene

HapMap Linkage Disequilibrium report
MIR625

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR625 Gene

Disorders for MIR625 Gene

Relevant External Links for MIR625

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR625

No disorders were found for MIR625 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR625 Gene

Publications for MIR625 Gene

  1. miR-625 suppresses tumour migration and invasion by targeting IGF2BP1 in hepatocellular carcinoma. (PMID: 24632613) Zhou X. … Yun J.P. (Oncogene 2015) 3 67
  2. miR-625 down-regulation promotes proliferation and invasion in esophageal cancer by targeting Sox2. (PMID: 24508466) Wang Z. … Xie Z. (FEBS Lett. 2014) 3
  3. High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer. (PMID: 23506979) Rasmussen M.H. … Andersen C.L. (Mol Oncol 2013) 3
  4. Decreased expression of microRNA-625 is associated with tumor metastasis and poor prognosis in patients with colorectal cancer. (PMID: 23861214) Lou X. … Yang J. (J Surg Oncol 2013) 3
  5. Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK. (PMID: 22677169) Wang M. … Liu B. (FEBS Lett. 2012) 3

Products for MIR625 Gene

Sources for MIR625 Gene

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