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Aliases for MIR622 Gene

Subcategory (RNA class) for MIR622 Gene


Quality Score for this RNA gene is


Aliases for MIR622 Gene

  • MicroRNA 622 2 3 5
  • Hsa-Mir-622 3
  • MIRN622 3

External Ids for MIR622 Gene

ORGUL Members for MIR622 Gene

Previous HGNC Symbols for MIR622 Gene

  • MIRN622

Previous GeneCards Identifiers for MIR622 Gene

  • GC13P089683
  • GC13P090886
  • GC13P090888
  • GC13P090891
  • GC13P090894
  • GC13P090897
  • GC13P090900
  • GC13P090903
  • GC13P090906
  • GC13P090911
  • GC13P090916
  • GC13P090920

Summaries for MIR622 Gene

Entrez Gene Summary for MIR622 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR622 Gene

MIR622 (MicroRNA 622) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR622 Gene

Genomics for MIR622 Gene

Genomic Location for MIR622 Gene

90,231,182 bp from pter
90,231,277 bp from pter
96 bases
Plus strand

Genomic View for MIR622 Gene

Genes around MIR622 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR622 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR622 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR622 Gene

No data available for Regulatory Elements for MIR622 Gene

Proteins for MIR622 Gene

Post-translational modifications for MIR622 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR622 Gene

Domains & Families for MIR622 Gene

Gene Families for MIR622 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR622: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR622 Gene

Function for MIR622 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR622 Gene

Localization for MIR622 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR622 Gene

Pathways & Interactions for MIR622 Gene

SuperPathways for MIR622 Gene

No Data Available

Interacting Proteins for MIR622 Gene

Gene Ontology (GO) - Biological Process for MIR622 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR622 Gene

Drugs & Compounds for MIR622 Gene

No Compound Related Data Available

Transcripts for MIR622 Gene

mRNA/cDNA for MIR622 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR622 Gene

No ASD Table

Relevant External Links for MIR622 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR622 Gene

mRNA expression in normal human tissues for MIR622 Gene

genes like me logo Genes that share expression patterns with MIR622: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR622 Gene

Orthologs for MIR622 Gene

Evolution for MIR622 Gene

Gene Tree for MIR622 (if available)
Gene Tree for MIR622 (if available)

No data available for Orthologs for MIR622 Gene

Paralogs for MIR622 Gene

No data available for Paralogs for MIR622 Gene

Variants for MIR622 Gene

Sequence variations from dbSNP and Humsavar for MIR622 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs7989199 -- 90,229,508(+) CTGGA(A/G)CTGGA upstream-variant-2KB
rs12857240 -- 90,231,129(+) CTCAC(C/G)AAGAT upstream-variant-2KB
rs74102260 -- 90,230,958(+) TCATT(A/G)ATGAC upstream-variant-2KB
rs73583155 -- 90,230,364(+) CTCGC(C/T)CTCCT upstream-variant-2KB
rs73583157 -- 90,230,483(+) CCATC(A/G/T)TCTAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR622 Gene

Variant ID Type Subtype PubMed ID
nsv456064 CNV Loss 19166990
dgv1772n71 CNV Gain 21882294
nsv900877 CNV Gain 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR622 Gene

Disorders for MIR622 Gene

Relevant External Links for MIR622

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR622 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR622 Gene

Publications for MIR622 Gene

  1. MiR-622 suppresses proliferation, invasion and migration by directly targeting activating transcription factor 2 in glioma cells. (PMID: 25258251) Zhang R. … Wang H. (J. Neurooncol. 2015) 3 67
  2. MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol. (PMID: 22016468) Han Z. … Jiang Y. (Carcinogenesis 2012) 3
  3. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PMID: 22219177) Tao S. … Sun J. (Carcinogenesis 2012) 3
  4. Down-regulation of miR-622 in gastric cancer promotes cellular invasion and tumor metastasis by targeting ING1 gene. (PMID: 21528065) Guo X.B. … Li C.S. (World J. Gastroenterol. 2011) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR622 Gene

Sources for MIR622 Gene