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Aliases for MIR621 Gene

Subcategory (RNA class) for MIR621 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR621 Gene

  • MicroRNA 621 2 3
  • Hsa-Mir-621 3
  • MIRN621 3

External Ids for MIR621 Gene

ORGUL Members for MIR621 Gene

Previous Symbols for MIR621 Gene

  • MIRN621

Summaries for MIR621 Gene

Entrez Gene Summary for MIR621 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR621 Gene

MIR621 (MicroRNA 621) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR621 Gene

Genomics for MIR621 Gene

Genomic Location for MIR621 Gene

Start:
40,810,766 bp from pter
End:
40,810,861 bp from pter
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR621 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR621 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR621 Gene

No data available for Regulatory Elements for MIR621 Gene

Proteins for MIR621 Gene

Post-translational modifications for MIR621 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR621 Gene

Domains for MIR621 Gene

Gene Families for MIR621 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR621: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR621 Gene

Function for MIR621 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR621 Gene

Localization for MIR621 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR621 Gene

Pathways for MIR621 Gene

SuperPathways for MIR621 Gene

No Data Available

Interacting Proteins for MIR621 Gene

Gene Ontology (GO) - Biological Process for MIR621 Gene

None

No data available for Pathways by source for MIR621 Gene

Transcripts for MIR621 Gene

mRNA/cDNA for MIR621 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR621 Gene

No ASD Table

Relevant External Links for MIR621 Gene

GeneLoc Exon Structure for
MIR621
ECgene alternative splicing isoforms for
MIR621

Expression for MIR621 Gene

mRNA expression in normal human tissues for MIR621 Gene

mRNA differential expression in normal tissues according to GTEx for MIR621 Gene

This gene is overexpressed in Liver (15.3) and Pancreas (6.2).
genes like me logo Genes that share expressions with MIR621: view

Orthologs for MIR621 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR621 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-621 37
  • 99 (a)
OneToOne
Species with no ortholog for MIR621:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR621 Gene

ENSEMBL:
Gene Tree for MIR621 (if available)
TreeFam:
Gene Tree for MIR621 (if available)

Paralogs for MIR621 Gene

No data available for Paralogs for MIR621 Gene

Variants for MIR621 Gene

Relevant External Links for MIR621 Gene

HapMap Linkage Disequilibrium report
MIR621

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR621 Gene

Disorders for MIR621 Gene

No disorders were found for MIR621 Gene.

No data available for UniProtKB/Swiss-Prot for MIR621 Gene

Publications for MIR621 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for MIR621 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR621
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR621
    • Block miRNA regulation of MIR621 using miScript Target Protectors

    Sources for MIR621 Gene

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