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Aliases for MIR620 Gene

Subcategory (RNA class) for MIR620 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR620 Gene

  • MicroRNA 620 2 3 5
  • Hsa-Mir-620 3
  • MIRN620 3

External Ids for MIR620 Gene

Previous HGNC Symbols for MIR620 Gene

  • MIRN620

Previous GeneCards Identifiers for MIR620 Gene

  • GC12U901028
  • GC12M115072
  • GC12M116586

Summaries for MIR620 Gene

Entrez Gene Summary for MIR620 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR620 Gene

MIR620 (MicroRNA 620) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR620 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR620

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR620 Gene

Genomics for MIR620 Gene

Regulatory Elements for MIR620 Gene

Enhancers for MIR620 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F116120 1.7 FANTOM5 Ensembl ENCODE 11.7 +25.1 25054 6.8 PKNOX1 ARNT MLX CREB3L1 SIN3A FEZF1 ZNF2 YY1 ZNF766 CBX5 FBXW8 MAP1LC3B2 MED13L MIR620 HRK GC12M116089 GC12P116137
GH12F116171 1.1 Ensembl ENCODE 12 -23.5 -23547 2.4 HDAC1 PKNOX1 ATF1 SIN3A RAD21 ETV6 CREM ZNF362 ZNF654 JUNB MIR620 MED13L ENSG00000271579 SNRPGP18 ENSG00000258337
GH12F116202 0.8 Ensembl ENCODE 12 -53.8 -53847 1.0 PKNOX1 GFI1B KDM1A ZBTB17 MIR620 PIR52842 ENSG00000258337
GH12F116176 0.7 Ensembl 11.6 -27.7 -27747 0.8 HDAC1 BCOR SMARCA5 ZMYM3 NFXL1 GATA3 HDAC2 SMARCA4 ADNP ZNF580 MIR620 ENSG00000258337 SNRPGP18
GH12F116190 0.7 Ensembl 11.1 -42.5 -42547 0.8 PKNOX1 HLF ZMYM3 KLF17 ZNF335 ZNF664 ZNF366 SCRT2 ZNF600 SP7 MIR620 ENSG00000258337 PIR52842
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR620 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR620 Gene

Chromosome:
12
Start:
116,148,560 bp from pter
End:
116,148,654 bp from pter
Size:
95 bases
Orientation:
Minus strand

Genomic View for MIR620 Gene

Genes around MIR620 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR620 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR620 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR620 Gene

ORGUL Member Location for MIR620 Gene

ORGUL Member Location for MIR620 gene

Proteins for MIR620 Gene

Post-translational modifications for MIR620 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR620 Gene

Domains & Families for MIR620 Gene

Gene Families for MIR620 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR620: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR620 Gene

Function for MIR620 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR620 Gene

Localization for MIR620 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR620 Gene

Pathways & Interactions for MIR620 Gene

SuperPathways for MIR620 Gene

No Data Available

Interacting Proteins for MIR620 Gene

Gene Ontology (GO) - Biological Process for MIR620 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR620 Gene

Transcripts for MIR620 Gene

fRNAdb Secondary structures for MIR620 Gene

  • FR238828

mRNA/cDNA for MIR620 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR620 Gene

No ASD Table

Relevant External Links for MIR620 Gene

GeneLoc Exon Structure for
MIR620
ECgene alternative splicing isoforms for
MIR620

Expression for MIR620 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR620 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR620 Gene:

MIR620
genes like me logo Genes that share expression patterns with MIR620: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR620 Gene

Orthologs for MIR620 Gene

Evolution for MIR620 Gene

ENSEMBL:
Gene Tree for MIR620 (if available)
TreeFam:
Gene Tree for MIR620 (if available)

No data available for Orthologs for MIR620 Gene

Paralogs for MIR620 Gene

No data available for Paralogs for MIR620 Gene

Variants for MIR620 Gene

Sequence variations from dbSNP and Humsavar for MIR620 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10549054 -- 116,148,610(+) ATATC(-/TA)TATAT intron-variant, nc-transcript-variant
rs10678970 -- 116,148,065(+) AAAAA(-/AAAAAAA)GAGGG intron-variant, downstream-variant-500B
rs111475859 -- 116,149,093(+) TGCAC(C/T)GTACC intron-variant, upstream-variant-2KB
rs112210728 -- 116,149,713(+) ATACA(G/T)ATGAC intron-variant, upstream-variant-2KB
rs113328518 -- 116,148,628(+) ATATA(-/TATA)CGGAG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR620 Gene

Variant ID Type Subtype PubMed ID
nsv832522 CNV loss 17160897
nsv952488 CNV duplication 24416366

Relevant External Links for MIR620 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR620

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR620 Gene

Disorders for MIR620 Gene

Relevant External Links for MIR620

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR620

No disorders were found for MIR620 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR620 Gene

Publications for MIR620 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3 64
  2. GPC5, a tumor suppressor, is regulated by miR-620 in lung adenocarcinoma. (PMID: 24682381) Zhao Z. … Cheng L. (Mol Med Rep 2014) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR620 Gene

Sources for MIR620 Gene

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