Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR617 Gene

Subcategory (RNA class) for MIR617 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR617 Gene

  • MicroRNA 617 2 3
  • Hsa-Mir-617 3
  • MIRN617 3

External Ids for MIR617 Gene

Previous Symbols for MIR617 Gene

  • MIRN617

Summaries for MIR617 Gene

Entrez Gene Summary for MIR617 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR617 Gene

MIR617 (MicroRNA 617) is a RNA Gene, and belongs to miRNA RNA class.

fRNAdb sequence ontologies for MIR617 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR617

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR617 Gene

Genomics for MIR617 Gene

Genomic Location for MIR617 Gene

Start:
80,832,533 bp from pter
End:
80,832,629 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR617 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR617 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR617 Gene

ORGUL Member Location for MIR617 Gene

ORGUL Member Location for MIR617 gene

No data available for Regulatory Elements for MIR617 Gene

Proteins for MIR617 Gene

Post-translational modifications for MIR617 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR617 Gene

Domains for MIR617 Gene

Gene Families for MIR617 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR617: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR617 Gene

Function for MIR617 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR617 Gene

Localization for MIR617 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR617 Gene

Pathways for MIR617 Gene

SuperPathways for MIR617 Gene

No Data Available

Interacting Proteins for MIR617 Gene

Gene Ontology (GO) - Biological Process for MIR617 Gene

None

No data available for Pathways by source for MIR617 Gene

Transcripts for MIR617 Gene

fRNAdb Secondary structures for MIR617 Gene

  • FR117298
  • hsa-miR-617_MIMAT0003286_Homo_sapiens_miR-617_mature

mRNA/cDNA for MIR617 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR617 Gene

No ASD Table

Relevant External Links for MIR617 Gene

GeneLoc Exon Structure for
MIR617
ECgene alternative splicing isoforms for
MIR617

Expression for MIR617 Gene

mRNA expression in normal human tissues for MIR617 Gene

genes like me logo Genes that share expressions with MIR617: view

Orthologs for MIR617 Gene

Evolution for MIR617 Gene

ENSEMBL:
Gene Tree for MIR617 (if available)
TreeFam:
Gene Tree for MIR617 (if available)

No data available for Orthologs for MIR617 Gene

Paralogs for MIR617 Gene

No data available for Paralogs for MIR617 Gene

Variants for MIR617 Gene

Relevant External Links for MIR617 Gene

HapMap Linkage Disequilibrium report
MIR617

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR617 Gene

Disorders for MIR617 Gene

No disorders were found for MIR617 Gene.

No data available for UniProtKB/Swiss-Prot for MIR617 Gene

Publications for MIR617 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for MIR617 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR617
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR617
    • Block miRNA regulation of MIR617 using miScript Target Protectors

    Sources for MIR617 Gene

    Back to Top

    Content