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Aliases for MIR615 Gene

Subcategory (RNA class) for MIR615 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR615 Gene

  • MicroRNA 615 2 3
  • Hsa-Mir-615 3
  • MIRN615 3

External Ids for MIR615 Gene

ORGUL Members for MIR615 Gene

Previous Symbols for MIR615 Gene

  • MIRN615

Summaries for MIR615 Gene

Entrez Gene Summary for MIR615 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR615 Gene

MIR615 (MicroRNA 615) is a RNA Gene, and belongs to miRNA RNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR615 Gene

Genomics for MIR615 Gene

Genomic Location for MIR615 Gene

Start:
54,033,950 bp from pter
End:
54,034,045 bp from pter
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR615 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR615 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR615 Gene

No data available for Regulatory Elements for MIR615 Gene

Proteins for MIR615 Gene

Post-translational modifications for MIR615 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR615 Gene

Domains for MIR615 Gene

Gene Families for MIR615 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR615: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR615 Gene

Function for MIR615 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR615 Gene

Localization for MIR615 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR615 Gene

Pathways for MIR615 Gene

SuperPathways for MIR615 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR615: view

Pathways by source for MIR615 Gene

1 KEGG pathway for MIR615 Gene

Interacting Proteins for MIR615 Gene

Gene Ontology (GO) - Biological Process for MIR615 Gene

None

Transcripts for MIR615 Gene

mRNA/cDNA for MIR615 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR615 Gene

No ASD Table

Relevant External Links for MIR615 Gene

GeneLoc Exon Structure for
MIR615
ECgene alternative splicing isoforms for
MIR615

Expression for MIR615 Gene

mRNA expression in normal human tissues for MIR615 Gene

genes like me logo Genes that share expressions with MIR615: view

Orthologs for MIR615 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR615 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-615 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-615 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-615 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir615 37
  • 98 (a)
OneToOne
Species with no ortholog for MIR615:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR615 Gene

ENSEMBL:
Gene Tree for MIR615 (if available)
TreeFam:
Gene Tree for MIR615 (if available)

Paralogs for MIR615 Gene

No data available for Paralogs for MIR615 Gene

Variants for MIR615 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR615 Gene

Variant ID Type Subtype PubMed ID
nsv826379 CNV Gain 20364138
nsv899100 CNV Loss 21882294
dgv512e1 CNV Complex 17122850
nsv428282 CNV Gain 18775914
nsv832418 CNV Loss 17160897

Relevant External Links for MIR615 Gene

HapMap Linkage Disequilibrium report
MIR615

No data available for Sequence variations from dbSNP and Humsavar for MIR615 Gene

Disorders for MIR615 Gene

No disorders were found for MIR615 Gene.

No data available for UniProtKB/Swiss-Prot for MIR615 Gene

Publications for MIR615 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. miR-615-3p promotes the phagocytic capacity of splenic macrophages by targeting ligand-dependent nuclear receptor corepressor in cirrhosis-related portal hypertension. (PMID: 21565892) Jiang A. … Yang J. (Exp. Biol. Med. (Maywood) 2011) 3
  5. miR-615-5p is restrictedly expressed in cirrhotic and cancerous liver tissues and its overexpression alleviates the tumorigenic effects in hepatocellular carcinoma. (PMID: 22819824) El Tayebi H.M. … Abdelaziz A.I. (FEBS Lett. 2012) 3

Products for MIR615 Gene

Sources for MIR615 Gene

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