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Aliases for MIR614 Gene

Subcategory (RNA class) for MIR614 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR614 Gene

  • MicroRNA 614 2 3 5
  • Hsa-Mir-614 3
  • MIRN614 3

External Ids for MIR614 Gene

ORGUL Members for MIR614 Gene

Previous HGNC Symbols for MIR614 Gene

  • MIRN614

Previous GeneCards Identifiers for MIR614 Gene

  • GC12P012961
  • GC12P013068
  • GC12P012918
  • GC12P012891
  • GC12P012916

Summaries for MIR614 Gene

Entrez Gene Summary for MIR614 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR614 Gene

MIR614 (MicroRNA 614) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are GPCRs, Class C Metabotropic glutamate, pheromone.

Additional gene information for MIR614 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR614 Gene

Genomics for MIR614 Gene

Regulatory Elements for MIR614 Gene

Enhancers for MIR614 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H013193 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.9 +287.3 287264 19 TBP PKNOX1 NFIB KLF17 SIN3A FEZF1 BATF RAD21 RFX5 YY1 HTR7P1 MIR614 GSG1 DDX47 GPRC5D-AS1 ENSG00000255621 HEBP1 ENSG00000221611 LOH12CR2 ENSG00000256011
GH12H013221 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.3 +307.2 307198 3 FOXA2 NFIB SIN3A DNMT3B ZNF155 RCOR1 FOS EGR2 CEBPB ZNF217 DDX47 MIR614 ENSG00000256011 GSG1 HEBP1 GC12M013223 GC12P013222
GH12H012869 1.5 Ensembl ENCODE dbSUPER 11.1 -43.3 -43290 5 PKNOX1 FOXA2 SIN3A FEZF1 BRCA1 KLF7 FOS DEK SREBF1 NFIL3 MIR614 RPL13AP20 PIR33493
GH12H012834 1.5 Ensembl ENCODE dbSUPER 10.9 -77.2 -77246 8 PKNOX1 SIN3A FEZF1 BRCA1 ZNF2 GTF3C2 ZNF121 GLIS2 KLF7 FOS DDX47 RPL13AP20 GPRC5A LOC100506248 MIR614 ENSG00000256011 GPRC5D-AS1 GPRC5D LRP6 GC12P012833
GH12H013177 1.5 FANTOM5 Ensembl ENCODE dbSUPER 9.9 +263.2 263202 2 KLF1 NFIB INSM2 KLF17 MAX NR2F2 GLIS2 ZBTB48 POLR2A GLIS1 GSG1 MIR614 EMP1 GC12M013185 GC12P013156
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR614 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR614 Gene

Chromosome:
12
Start:
12,915,829 bp from pter
End:
12,915,918 bp from pter
Size:
90 bases
Orientation:
Plus strand

Genomic View for MIR614 Gene

Genes around MIR614 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR614 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR614 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR614 Gene

Proteins for MIR614 Gene

Post-translational modifications for MIR614 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR614 Gene

Domains & Families for MIR614 Gene

Gene Families for MIR614 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR614: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR614 Gene

Function for MIR614 Gene

Phenotypes From GWAS Catalog for MIR614 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR614
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR614 Gene

Localization for MIR614 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR614 Gene

Pathways & Interactions for MIR614 Gene

genes like me logo Genes that share pathways with MIR614: view

Pathways by source for MIR614 Gene

1 BioSystems pathway for MIR614 Gene

Interacting Proteins for MIR614 Gene

Gene Ontology (GO) - Biological Process for MIR614 Gene

None

No data available for SIGNOR curated interactions for MIR614 Gene

Drugs & Compounds for MIR614 Gene

No Compound Related Data Available

Transcripts for MIR614 Gene

mRNA/cDNA for MIR614 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR614
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR614 Gene

No ASD Table

Relevant External Links for MIR614 Gene

GeneLoc Exon Structure for
MIR614
ECgene alternative splicing isoforms for
MIR614

Expression for MIR614 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR614 Gene

mRNA differential expression in normal tissues according to GTEx for MIR614 Gene

This gene is overexpressed in Lung (x12.5).

NURSA nuclear receptor signaling pathways regulating expression of MIR614 Gene:

MIR614
genes like me logo Genes that share expression patterns with MIR614: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR614 Gene

Orthologs for MIR614 Gene

Evolution for MIR614 Gene

ENSEMBL:
Gene Tree for MIR614 (if available)
TreeFam:
Gene Tree for MIR614 (if available)

No data available for Orthologs for MIR614 Gene

Paralogs for MIR614 Gene

No data available for Paralogs for MIR614 Gene

Variants for MIR614 Gene

Sequence variations from dbSNP and Humsavar for MIR614 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1002034384 -- 12,915,407(+) GCTCT(A/G)TTGCC upstream-variant-2KB
rs1002067326 -- 12,915,773(+) GGCCT(C/T)TGAAA upstream-variant-2KB
rs1005538346 -- 12,914,702(+) CCTCC(A/G/T)CATCC upstream-variant-2KB
rs1005777285 -- 12,914,866(+) CTGCC(C/T)GCCTT upstream-variant-2KB
rs1005915684 -- 12,916,062(+) ACCAA(A/G)GGATA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR614 Gene

Variant ID Type Subtype PubMed ID
esv2745567 CNV deletion 23290073
esv3628627 CNV gain 21293372
nsv1159986 CNV deletion 26073780
nsv832333 CNV gain 17160897

Relevant External Links for MIR614 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR614

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR614 Gene

Disorders for MIR614 Gene

Relevant External Links for MIR614

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR614

No disorders were found for MIR614 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR614 Gene

Publications for MIR614 Gene

  1. [MiR-614 inhibited lung cancer cell invasion and proliferation via targeting PSA]. (PMID: 25342037) Lv F … Xue Q (Zhongguo fei ai za zhi = Chinese journal of lung cancer 2014) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60
  3. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 60

Products for MIR614 Gene

Sources for MIR614 Gene

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