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Aliases for MIR612 Gene

Subcategory (RNA class) for MIR612 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR612 Gene

  • MicroRNA 612 2 3
  • Hsa-Mir-612 3
  • MIRN612 3

External Ids for MIR612 Gene

ORGUL Members for MIR612 Gene

Previous HGNC Symbols for MIR612 Gene

  • MIRN612

Previous GeneCards Identifiers for MIR612 Gene

  • GC11P064969
  • GC11P065211
  • GC11P065448

Summaries for MIR612 Gene

Entrez Gene Summary for MIR612 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR612 Gene

MIR612 (MicroRNA 612) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR612 Gene

Genomics for MIR612 Gene

Genomic Location for MIR612 Gene

Chromosome:
11
Start:
65,444,458 bp from pter
End:
65,444,557 bp from pter
Size:
100 bases
Orientation:
Plus strand

Genomic View for MIR612 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR612 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR612 Gene

No data available for Regulatory Elements for MIR612 Gene

Proteins for MIR612 Gene

Post-translational modifications for MIR612 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR612 Gene

Domains & Families for MIR612 Gene

Gene Families for MIR612 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR612: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR612 Gene

Function for MIR612 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR612 Gene

Localization for MIR612 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR612 Gene

Pathways & Interactions for MIR612 Gene

SuperPathways for MIR612 Gene

No Data Available

Interacting Proteins for MIR612 Gene

Gene Ontology (GO) - Biological Process for MIR612 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR612 Gene

Drugs & Compounds for MIR612 Gene

No Compound Related Data Available

Transcripts for MIR612 Gene

mRNA/cDNA for MIR612 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR612 Gene

No ASD Table

Relevant External Links for MIR612 Gene

GeneLoc Exon Structure for
MIR612
ECgene alternative splicing isoforms for
MIR612

Expression for MIR612 Gene

mRNA expression in normal human tissues for MIR612 Gene

genes like me logo Genes that share expression patterns with MIR612: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR612 Gene

Orthologs for MIR612 Gene

Evolution for MIR612 Gene

ENSEMBL:
Gene Tree for MIR612 (if available)
TreeFam:
Gene Tree for MIR612 (if available)

No data available for Orthologs for MIR612 Gene

Paralogs for MIR612 Gene

No data available for Paralogs for MIR612 Gene

Variants for MIR612 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR612 Gene

Variant ID Type Subtype PubMed ID
nsv526181 CNV Gain 19592680
esv2422285 CNV Deletion 17116639
dgv1175n71 CNV Loss 21882294
nsv897717 CNV Loss 21882294
nsv897718 CNV Loss 21882294
nsv897719 CNV Loss 21882294

Relevant External Links for MIR612 Gene

HapMap Linkage Disequilibrium report
MIR612

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR612 Gene

Disorders for MIR612 Gene

Relevant External Links for MIR612

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR612
genes like me logo Genes that share disorders with MIR612: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR612 Gene

Publications for MIR612 Gene

  1. MiR-612 suppresses the stemness of liver cancer via Wnt/I^-catenin signaling. (PMID: 24704424) Tang J. … Wu W.Z. (Biochem. Biophys. Res. Commun. 2014) 67
  2. Noncoding RNA-related polymorphisms in pediatric acute lymphoblastic leukemia susceptibility. (PMID: 24618566) Gutierrez-Camino A. … Garcia-Orad A. (Pediatr. Res. 2014) 67
  3. miR-612 suppresses the invasive-metastatic cascade in hepatocellular carcinoma. (PMID: 23478189) Tao Z.H. … Wu W.Z. (J. Exp. Med. 2013) 67
  4. Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms. (PMID: 23077621) Kim H.K. … Chanock S.J. (PLoS ONE 2012) 67
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR612 Gene

Sources for MIR612 Gene

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