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Aliases for MIR611 Gene

Subcategory (RNA class) for MIR611 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR611 Gene

  • MicroRNA 611 2 3 5
  • Hsa-Mir-611 3
  • MIRN611 3

External Ids for MIR611 Gene

Previous HGNC Symbols for MIR611 Gene

  • MIRN611

Previous GeneCards Identifiers for MIR611 Gene

  • GC11M061318
  • GC11M061559

Summaries for MIR611 Gene

Entrez Gene Summary for MIR611 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR611 Gene

MIR611 (MicroRNA 611) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR611 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR611

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR611 Gene

Genomics for MIR611 Gene

Regulatory Elements for MIR611 Gene

Enhancers for MIR611 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G061731 1.2 Ensembl ENCODE 11.6 +59.6 59593 2.1 PKNOX1 ATF1 ARNT ARID4B SIN3A BRCA1 ZNF48 ZNF143 DEK MXD4 DAGLA MYRF DKFZP434K028 FEN1 MIR611 TMEM258 SYT7 PIR41833
GH11G061819 1.1 Ensembl ENCODE 10.7 -28.0 -28006 1.7 PKNOX1 EGR1 SCRT2 FOS EGR2 SP3 ZNF592 SP1 HNF4A PRDM1 FADS2 MIR611 TMEM258 FEN1 MIR1908 PIR43939
GH11G061787 1.1 ENCODE dbSUPER 0.7 +4.2 4165 0.9 CTCF KLF1 MXI1 ZSCAN4 ARID4B CHD7 RAD21 TEAD3 ZFHX2 POLR2A FADS2 MIR611 LOC100129473
GH11G061774 1.4 Ensembl ENCODE dbSUPER 0.4 +16.2 16202 3.3 PKNOX1 AGO1 YY1 ZNF766 ZNF143 FOS DEK REST MIER2 CREB3 FADS2 B3GAT3 LOC100129473 MIR611
GH11G061762 1.5 Ensembl ENCODE dbSUPER 0.3 +24.1 24104 11.0 PKNOX1 ATF1 FOXA2 ARID4B ZNF48 YY1 ZNF121 GLIS2 ZNF143 KDM4B FADS2 BEST1 MYRF LOC100129473 MIR611
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR611 on UCSC Golden Path with GeneCards custom track

Promoters for MIR611 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000040338 -239 2001 HDGF PKNOX1 CREB3L1 ARNT AGO1 WRNIP1 ARID4B SIN3A DMAP1 ZBTB7B

Genomic Location for MIR611 Gene

Chromosome:
11
Start:
61,792,495 bp from pter
End:
61,792,561 bp from pter
Size:
67 bases
Orientation:
Minus strand

Genomic View for MIR611 Gene

Genes around MIR611 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR611 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR611 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR611 Gene

ORGUL Member Location for MIR611 Gene

ORGUL Member Location for MIR611 gene

Proteins for MIR611 Gene

Post-translational modifications for MIR611 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR611 Gene

Domains & Families for MIR611 Gene

Gene Families for MIR611 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR611: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR611 Gene

Function for MIR611 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR611 Gene

Localization for MIR611 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR611 Gene

Pathways & Interactions for MIR611 Gene

SuperPathways for MIR611 Gene

No Data Available

Interacting Proteins for MIR611 Gene

Gene Ontology (GO) - Biological Process for MIR611 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR611 Gene

Transcripts for MIR611 Gene

fRNAdb Secondary structures for MIR611 Gene

  • FR390145

mRNA/cDNA for MIR611 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR611 Gene

No ASD Table

Relevant External Links for MIR611 Gene

GeneLoc Exon Structure for
MIR611
ECgene alternative splicing isoforms for
MIR611

Expression for MIR611 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR611 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR611 Gene:

MIR611
genes like me logo Genes that share expression patterns with MIR611: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR611 Gene

Orthologs for MIR611 Gene

Evolution for MIR611 Gene

ENSEMBL:
Gene Tree for MIR611 (if available)
TreeFam:
Gene Tree for MIR611 (if available)

No data available for Orthologs for MIR611 Gene

Paralogs for MIR611 Gene

No data available for Paralogs for MIR611 Gene

Variants for MIR611 Gene

Sequence variations from dbSNP and Humsavar for MIR611 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1002676540 -- 61,792,969(+) ACCGC(A/C)TGCCC upstream-variant-2KB, utr-variant-5-prime
rs1002728911 -- 61,793,307(+) TCCTG(-/CCTA)CCTGT intron-variant, upstream-variant-2KB
rs1005841801 -- 61,794,508(+) GAGTT(C/T)TCCAG intron-variant, upstream-variant-2KB
rs1006583422 -- 61,792,948(+) GAAGG(-/GA)GAGAG upstream-variant-2KB, utr-variant-5-prime
rs1007011508 -- 61,794,088(+) CCCAA(A/G)GTGCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR611 Gene

Variant ID Type Subtype PubMed ID
nsv343 CNV insertion 18451855
nsv528697 CNV loss 19592680

Relevant External Links for MIR611 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR611

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR611 Gene

Disorders for MIR611 Gene

Relevant External Links for MIR611

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR611

No disorders were found for MIR611 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR611 Gene

Publications for MIR611 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3 64
  2. An atlas of genetic influences on human blood metabolites. (PMID: 24816252) Shin S.Y. … Soranzo N. (Nat. Genet. 2014) 3 64
  3. Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. (PMID: 21829377) Lemaitre R.N. … Steffen L.M. (PLoS Genet. 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR611 Gene

Sources for MIR611 Gene

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