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Aliases for MIR609 Gene

Subcategory (RNA class) for MIR609 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR609 Gene

  • MicroRNA 609 2 3 5
  • Hsa-Mir-609 3
  • MIRN609 3

External Ids for MIR609 Gene

Previous HGNC Symbols for MIR609 Gene

  • MIRN609

Previous GeneCards Identifiers for MIR609 Gene

  • GC10M105969

Summaries for MIR609 Gene

Entrez Gene Summary for MIR609 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR609 Gene

MIR609 (MicroRNA 609) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR609 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR609

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR609 Gene

Genomics for MIR609 Gene

Regulatory Elements for MIR609 Gene

Enhancers for MIR609 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G104258 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.6 -41.5 -41529 3.0 CBX3 TAL1 JUN YY1 FOSL1 TCF12 POLR2A NCOR1 TRIM24 FOS GSTO2 GSTO1 MIR609 SFR1 SLK CFAP58 ITPRIP GC10M104249 MIR4482
GH10G104246 1 Ensembl ENCODE 11 -28.3 -28319 2.0 CBX3 TAL1 NFXL1 FOSL1 TCF12 CBX5 NCOR1 ADNP TRIM24 FOS GSTO2 MIR609 GSTO1 GC10M104249
GH10G103884 0.9 ENCODE dbSUPER 9.9 +334.0 334046 0.2 CTCF ZNF654 MXI1 TRIM22 MXD4 REST ZNF2 RAD21 RFX5 ZKSCAN1 STN1 SH3PXD2A MIR609 PIR55313 GC10M103884 GC10M103885
GH10G103878 0.8 ENCODE dbSUPER 9.9 +337.7 337699 5.4 CTCF MXI1 ZNF146 ZNF680 EP300 STN1 SH3PXD2A MIR936 MIR609 ENSG00000260461 GC10M103883 PIR46931
GH10G104242 0.7 ENCODE 11 -24.7 -24664 1.6 SOX5 SOX13 GATAD2A TFE3 SAP130 TEAD1 NFIA FOXA3 CEBPB CEBPG GSTO2 MIR609 ITPRIP GSTO1 GC10M104249
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR609 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR609 Gene

Chromosome:
10
Start:
104,218,789 bp from pter
End:
104,218,883 bp from pter
Size:
95 bases
Orientation:
Minus strand

Genomic View for MIR609 Gene

Genes around MIR609 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR609 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR609 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR609 Gene

ORGUL Member Location for MIR609 Gene

ORGUL Member Location for MIR609 gene

Proteins for MIR609 Gene

Post-translational modifications for MIR609 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR609 Gene

Domains & Families for MIR609 Gene

Gene Families for MIR609 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR609: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR609 Gene

Function for MIR609 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR609 Gene

Localization for MIR609 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR609 Gene

Pathways & Interactions for MIR609 Gene

SuperPathways for MIR609 Gene

No Data Available

Interacting Proteins for MIR609 Gene

Gene Ontology (GO) - Biological Process for MIR609 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR609 Gene

Drugs & Compounds for MIR609 Gene

No Compound Related Data Available

Transcripts for MIR609 Gene

fRNAdb Secondary structures for MIR609 Gene

  • hsa-miR-609_MIMAT0003277_Homo_sapiens_miR-609_mature

mRNA/cDNA for MIR609 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR609 Gene

No ASD Table

Relevant External Links for MIR609 Gene

GeneLoc Exon Structure for
MIR609
ECgene alternative splicing isoforms for
MIR609

Expression for MIR609 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR609 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR609 Gene:

MIR609
genes like me logo Genes that share expression patterns with MIR609: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR609 Gene

Orthologs for MIR609 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR609 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-609 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 35
  • 63 (a)
OneToOne
Species where no ortholog for MIR609 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR609 Gene

ENSEMBL:
Gene Tree for MIR609 (if available)
TreeFam:
Gene Tree for MIR609 (if available)

Paralogs for MIR609 Gene

No data available for Paralogs for MIR609 Gene

Variants for MIR609 Gene

Sequence variations from dbSNP and Humsavar for MIR609 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1003114284 -- 104,219,297(+) CACCT(C/T)CCAAA intron-variant, upstream-variant-2KB
rs1003114902 -- 104,220,026(+) AATCA(A/G)GTTAA intron-variant, upstream-variant-2KB
rs1003576137 -- 104,219,592(+) GAGTA(C/T)CCTTC intron-variant, upstream-variant-2KB
rs1004470779 -- 104,219,263(+) GTCAG(C/T)TACAA intron-variant, upstream-variant-2KB
rs1004790425 -- 104,218,527(+) TGGCC(A/G)AGGGG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR609 Gene

Variant ID Type Subtype PubMed ID
nsv831971 CNV gain 17160897

Relevant External Links for MIR609 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR609

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR609 Gene

Disorders for MIR609 Gene

Relevant External Links for MIR609

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR609

No disorders were found for MIR609 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR609 Gene

Publications for MIR609 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR609 Gene

Sources for MIR609 Gene

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