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Aliases for MIR6084 Gene

Subcategory (RNA class) for MIR6084 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR6084 Gene

  • MicroRNA 6084 2 3 5
  • MicroRNA Mir-6084 3
  • Hsa-Mir-6084 3

External Ids for MIR6084 Gene

Previous GeneCards Identifiers for MIR6084 Gene

  • GC01U904152

Summaries for MIR6084 Gene

Entrez Gene Summary for MIR6084 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6084 Gene

MIR6084 (MicroRNA 6084) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Pink/Parkin Mediated Mitophagy and Parkinsons Disease Pathway.

Additional gene information for MIR6084 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6084 Gene

Genomics for MIR6084 Gene

Regulatory Elements for MIR6084 Gene

Enhancers for MIR6084 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H020632 1.1 ENCODE 0.7 +0.3 336 2 PKNOX1 ARNT ARID4B SIN3A ZNF2 SLC30A9 ZNF766 ZNF143 SP5 MXD4 PINK1 CDA PIR40855 MIR6084
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR6084 on UCSC Golden Path with GeneCards custom track

Promoters for MIR6084 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000002643 221 1401 ARNT ARID4B SIN3A ZNF2 SLC30A9 ZNF766 ZNF143 SP5 MXD4 ZC3H11A

Genomic Location for MIR6084 Gene

Chromosome:
1
Start:
20,633,679 bp from pter
End:
20,633,788 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR6084 Gene

Genes around MIR6084 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6084 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6084 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6084 Gene

Proteins for MIR6084 Gene

Post-translational modifications for MIR6084 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6084 Gene

Domains & Families for MIR6084 Gene

Gene Families for MIR6084 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6084: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6084 Gene

Function for MIR6084 Gene

Animal Model Products

miRNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6084 Gene

Localization for MIR6084 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6084 Gene

Pathways & Interactions for MIR6084 Gene

genes like me logo Genes that share pathways with MIR6084: view

Pathways by source for MIR6084 Gene

1 BioSystems pathway for MIR6084 Gene
2 Reactome pathways for MIR6084 Gene

Interacting Proteins for MIR6084 Gene

Gene Ontology (GO) - Biological Process for MIR6084 Gene

None

No data available for SIGNOR curated interactions for MIR6084 Gene

Drugs & Compounds for MIR6084 Gene

No Compound Related Data Available

Transcripts for MIR6084 Gene

mRNA/cDNA for MIR6084 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6084 Gene

No ASD Table

Relevant External Links for MIR6084 Gene

GeneLoc Exon Structure for
MIR6084
ECgene alternative splicing isoforms for
MIR6084

Expression for MIR6084 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6084 Gene:

MIR6084
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6084 Gene

Orthologs for MIR6084 Gene

Evolution for MIR6084 Gene

ENSEMBL:
Gene Tree for MIR6084 (if available)
TreeFam:
Gene Tree for MIR6084 (if available)

No data available for Orthologs for MIR6084 Gene

Paralogs for MIR6084 Gene

No data available for Paralogs for MIR6084 Gene

Variants for MIR6084 Gene

Sequence variations from dbSNP and Humsavar for MIR6084 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs148871409 Likely benign 20,633,892(+) AAAAC(A/C/T)GGCGG downstream-variant-500B, reference, missense
rs45530340 Likely benign 20,633,737(+) AGCCT(C/T)CCTAA nc-transcript-variant, reference, synonymous-codon
rs1057519104 Uncertain significance 20,633,717(+) AGCCT(C/T)GCAGG nc-transcript-variant, reference, missense
rs537679886 Uncertain significance 20,633,713(+) GCGGA(A/G)CCTCG nc-transcript-variant, reference, synonymous-codon
rs569753606 Uncertain significance 20,633,636(+) CCTAC(C/G)GCTTG upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR6084 Gene

Variant ID Type Subtype PubMed ID
nsv1076232 CNV deletion 25765185
nsv1126183 CNV deletion 24896259
nsv545731 CNV gain 21841781
nsv834369 CNV loss 17160897

Relevant External Links for MIR6084 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6084

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6084 Gene

Disorders for MIR6084 Gene

Relevant External Links for MIR6084

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR6084

No disorders were found for MIR6084 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6084 Gene

Publications for MIR6084 Gene

  1. Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. (PMID: 22282338) Voellenkle C … Martelli F (RNA (New York, N.Y.) 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR6084 Gene

Sources for MIR6084 Gene

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