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Aliases for MIR608 Gene

Subcategory (RNA class) for MIR608 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR608 Gene

  • MicroRNA 608 2 3
  • Hsa-Mir-608 3
  • MIRN608 3

External Ids for MIR608 Gene

ORGUL Members for MIR608 Gene

Previous Symbols for MIR608 Gene

  • MIRN608

Summaries for MIR608 Gene

Entrez Gene Summary for MIR608 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR608 Gene

MIR608 (MicroRNA 608) is an RNA Gene, and belongs to the miRNA class. Diseases associated with MIR608 include tendinopathy and esophageal cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR608 Gene

Genomics for MIR608 Gene

Genomic Location for MIR608 Gene

Start:
100,974,985 bp from pter
End:
100,975,084 bp from pter
Size:
100 bases
Orientation:
Plus strand

Genomic View for MIR608 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR608 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR608 Gene

No data available for Regulatory Elements for MIR608 Gene

Proteins for MIR608 Gene

Post-translational modifications for MIR608 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR608 Gene

Domains for MIR608 Gene

Gene Families for MIR608 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR608: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR608 Gene

Function for MIR608 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR608 Gene

Localization for MIR608 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR608 Gene

Pathways for MIR608 Gene

SuperPathways for MIR608 Gene

No Data Available

Interacting Proteins for MIR608 Gene

Gene Ontology (GO) - Biological Process for MIR608 Gene

None

No data available for Pathways by source for MIR608 Gene

Transcripts for MIR608 Gene

mRNA/cDNA for MIR608 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR608 Gene

No ASD Table

Relevant External Links for MIR608 Gene

GeneLoc Exon Structure for
MIR608
ECgene alternative splicing isoforms for
MIR608

Expression for MIR608 Gene

mRNA expression in normal human tissues for MIR608 Gene

genes like me logo Genes that share expressions with MIR608: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR608 Gene

Orthologs for MIR608 Gene

Evolution for MIR608 Gene

ENSEMBL:
Gene Tree for MIR608 (if available)
TreeFam:
Gene Tree for MIR608 (if available)

No data available for Orthologs for MIR608 Gene

Paralogs for MIR608 Gene

No data available for Paralogs for MIR608 Gene

Variants for MIR608 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR608 Gene

Variant ID Type Subtype PubMed ID
nsv831965 CNV Loss 17160897
nsv467443 CNV Loss 19166990
nsv517698 CNV Loss 19592680
nsv895961 CNV Loss 21882294

Relevant External Links for MIR608 Gene

HapMap Linkage Disequilibrium report
MIR608
Human Gene Mutation Database (HGMD)
MIR608

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR608 Gene

Disorders for MIR608 Gene

Relevant External Links for MIR608

Genetic Association Database (GAD)
MIR608
Human Genome Epidemiology (HuGE) Navigator
MIR608
genes like me logo Genes that share disorders with MIR608: view

No data available for UniProtKB/Swiss-Prot for MIR608 Gene

Publications for MIR608 Gene

  1. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y. … Wu X. (Cancer Prev Res (Phila) 2008) 3 48
  2. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 48
  3. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J. … Wu X. (Carcinogenesis 2010) 3 48
  4. Polymorphism rs4919510:C>G in mature sequence of human microRNA-608 contributes to the risk of HER2-positive breast cancer but not other subtypes. (PMID: 22586447) Huang A.J. … Shao Z.M. (PLoS ONE 2012) 3
  5. rs4919510 in hsa-mir-608 is associated with outcome but not risk of colorectal cancer. (PMID: 22606253) Ryan B.M. … Harris C.C. (PLoS ONE 2012) 3

Products for MIR608 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR608
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR608
    • Block miRNA regulation of MIR608 using miScript Target Protectors

    Sources for MIR608 Gene

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