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Aliases for MIR608 Gene

Subcategory (RNA class) for MIR608 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR608 Gene

  • MicroRNA 608 2 3 5
  • Hsa-Mir-608 3
  • MIRN608 3

External Ids for MIR608 Gene

ORGUL Members for MIR608 Gene

Previous HGNC Symbols for MIR608 Gene

  • MIRN608

Previous GeneCards Identifiers for MIR608 Gene

  • GC10P102725
  • GC10P102736

Summaries for MIR608 Gene

Entrez Gene Summary for MIR608 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR608 Gene

MIR608 (MicroRNA 608) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR608 Gene

Genomics for MIR608 Gene

Genomic Location for MIR608 Gene

Chromosome:
10
Start:
100,974,985 bp from pter
End:
100,975,084 bp from pter
Size:
100 bases
Orientation:
Plus strand

Genomic View for MIR608 Gene

Genes around MIR608 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR608 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR608 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR608 Gene

No data available for Regulatory Elements for MIR608 Gene

Proteins for MIR608 Gene

Post-translational modifications for MIR608 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR608 Gene

Domains & Families for MIR608 Gene

Gene Families for MIR608 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR608: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR608 Gene

Function for MIR608 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR608 Gene

Localization for MIR608 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR608 Gene

Pathways & Interactions for MIR608 Gene

SuperPathways for MIR608 Gene

No Data Available

Interacting Proteins for MIR608 Gene

Gene Ontology (GO) - Biological Process for MIR608 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR608 Gene

Drugs & Compounds for MIR608 Gene

No Compound Related Data Available

Transcripts for MIR608 Gene

mRNA/cDNA for MIR608 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR608 Gene

No ASD Table

Relevant External Links for MIR608 Gene

GeneLoc Exon Structure for
MIR608
ECgene alternative splicing isoforms for
MIR608

Expression for MIR608 Gene

mRNA expression in normal human tissues for MIR608 Gene

genes like me logo Genes that share expression patterns with MIR608: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR608 Gene

Orthologs for MIR608 Gene

Evolution for MIR608 Gene

ENSEMBL:
Gene Tree for MIR608 (if available)
TreeFam:
Gene Tree for MIR608 (if available)

No data available for Orthologs for MIR608 Gene

Paralogs for MIR608 Gene

No data available for Paralogs for MIR608 Gene

Variants for MIR608 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR608 Gene

Variant ID Type Subtype PubMed ID
nsv831965 CNV Loss 17160897
nsv467443 CNV Loss 19166990
nsv517698 CNV Loss 19592680
nsv895961 CNV Loss 21882294

Relevant External Links for MIR608 Gene

HapMap Linkage Disequilibrium report
MIR608
Human Gene Mutation Database (HGMD)
MIR608

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR608 Gene

Disorders for MIR608 Gene

Relevant External Links for MIR608

Genetic Association Database (GAD)
MIR608
Human Genome Epidemiology (HuGE) Navigator
MIR608
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR608

No disorders were found for MIR608 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR608 Gene

Publications for MIR608 Gene

  1. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 48 67
  2. Polymorphism in mature microRNA-608 sequence is associated with an increased risk of nasopharyngeal carcinoma. (PMID: 25861865) Qiu F. … Lu J. (Gene 2015) 3
  3. MicroRNAs targeting the immunomodulatory HLA-G gene: a new survey searching for microRNAs with potential to regulate HLA-G. (PMID: 25700346) Porto I.O. … Castelli E.C. (Mol. Immunol. 2015) 3
  4. MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. (PMID: 25385442) Akhtar N. … Haqqi T.M. ( 2015) 3
  5. Polymorphisms in microRNA genes as predictors of clinical outcomes in colorectal cancer patients. (PMID: 25368035) Pardini B. … Vodicka P. (Carcinogenesis 2015) 3

Products for MIR608 Gene

Sources for MIR608 Gene

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