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Aliases for MIR6075 Gene

Subcategory (RNA class) for MIR6075 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR6075 Gene

  • MicroRNA 6075 2 3 5
  • MicroRNA Mir-6075 3
  • Hsa-Mir-6075 3

External Ids for MIR6075 Gene

Previous GeneCards Identifiers for MIR6075 Gene

  • GC05U901982

Summaries for MIR6075 Gene

Entrez Gene Summary for MIR6075 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6075 Gene

MIR6075 (MicroRNA 6075) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6075 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6075 Gene

Genomics for MIR6075 Gene

Regulatory Elements for MIR6075 Gene

Enhancers for MIR6075 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H001511 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -5.1 -5148 9 PKNOX1 ZFP64 SIN3A ZBTB7B GLIS2 FOS TSHZ1 ZNF592 SREBF1 GLIS1 SLC6A3 TERT SLC6A18 LPCAT1 CTD-3080P12.3 SLC12A7 MIR6075
GH05H001521 1.3 ENCODE dbSUPER 0.4 -12.3 -12317 3 HDGF ATF1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 GLIS2 ZNF143 SLC6A3 LOC100132773 LPCAT1 MIR6075
GH05H001512 0.6 ENCODE dbSUPER 0.7 -0.6 -563 0 ZEB2 SLC6A3 TERT MIR6075 LPCAT1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR6075 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR6075 Gene

Chromosome:
5
Start:
1,510,762 bp from pter
End:
1,510,856 bp from pter
Size:
95 bases
Orientation:
Minus strand

Genomic View for MIR6075 Gene

Genes around MIR6075 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6075 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6075 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6075 Gene

Proteins for MIR6075 Gene

Post-translational modifications for MIR6075 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6075 Gene

Domains & Families for MIR6075 Gene

Gene Families for MIR6075 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6075: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6075 Gene

Function for MIR6075 Gene

Phenotypes From GWAS Catalog for MIR6075 Gene

Animal Model Products

miRNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6075 Gene

Localization for MIR6075 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6075 Gene

Pathways & Interactions for MIR6075 Gene

SuperPathways for MIR6075 Gene

No Data Available

Interacting Proteins for MIR6075 Gene

Gene Ontology (GO) - Biological Process for MIR6075 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6075 Gene

Drugs & Compounds for MIR6075 Gene

No Compound Related Data Available

Transcripts for MIR6075 Gene

mRNA/cDNA for MIR6075 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6075 Gene

No ASD Table

Relevant External Links for MIR6075 Gene

GeneLoc Exon Structure for
MIR6075
ECgene alternative splicing isoforms for
MIR6075

Expression for MIR6075 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6075 Gene:

MIR6075
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6075 Gene

Orthologs for MIR6075 Gene

Evolution for MIR6075 Gene

ENSEMBL:
Gene Tree for MIR6075 (if available)
TreeFam:
Gene Tree for MIR6075 (if available)

No data available for Orthologs for MIR6075 Gene

Paralogs for MIR6075 Gene

No data available for Paralogs for MIR6075 Gene

Variants for MIR6075 Gene

Sequence variations from dbSNP and Humsavar for MIR6075 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000431062 -- 1,510,802(+) TCTGT(A/G)GGACA intron-variant, nc-transcript-variant
rs1001490061 -- 1,512,139(+) CCCCA(C/T)GGCCA intron-variant, upstream-variant-2KB
rs1001556453 -- 1,511,541(+) CGCTC(A/G)CCCTA intron-variant, upstream-variant-2KB
rs1001836168 -- 1,511,916(+) CTGGG(A/G)ATGGC intron-variant, upstream-variant-2KB
rs1002429152 -- 1,512,689(+) GGGGC(A/T)CTGCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR6075 Gene

Variant ID Type Subtype PubMed ID
nsv1133013 OTHER inversion 24896259
nsv1147234 OTHER inversion 26484159
nsv596877 CNV loss 21841781
nsv596878 CNV loss 21841781

Relevant External Links for MIR6075 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6075

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6075 Gene

Disorders for MIR6075 Gene

Relevant External Links for MIR6075

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR6075

No disorders were found for MIR6075 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6075 Gene

Publications for MIR6075 Gene

  1. Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. (PMID: 22282338) Voellenkle C … Martelli F (RNA (New York, N.Y.) 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR6075 Gene

Sources for MIR6075 Gene

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