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Aliases for MIR606 Gene

Subcategory (RNA class) for MIR606 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR606 Gene

  • MicroRNA 606 2 3 5
  • Hsa-Mir-606 3
  • MIRN606 3

External Ids for MIR606 Gene

ORGUL Members for MIR606 Gene

Previous HGNC Symbols for MIR606 Gene

  • MIRN606

Previous GeneCards Identifiers for MIR606 Gene

  • GC10P076983
  • GC10P077312

Summaries for MIR606 Gene

Entrez Gene Summary for MIR606 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR606 Gene

MIR606 (MicroRNA 606) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR606 Gene

Genomics for MIR606 Gene

Regulatory Elements for MIR606 Gene

Enhancers for MIR606 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F075612 2.2 Ensembl ENCODE 10.9 +61.5 61532 2.4 PKNOX1 FEZF1 ZNF2 YY1 ZNF121 ZNF302 KLF7 ZNF263 ZNF488 ZNF518A C10orf11 ENSG00000234149 MIR606 ENSG00000236842 ZNF503 ZNF503-AS2 GC10M075584 GC10P075624
GH10F075770 1.6 FANTOM5 Ensembl ENCODE 10.3 +219.9 219930 3.7 PKNOX1 SIN3A FEZF1 DMAP1 ZNF2 ZNF48 YY1 FOS ZNF263 SP5 MIR606 C10orf11 ENSG00000236842 ZNF503 ZNF503-AS2 GC10P075790 GC10M075724
GH10F075610 0.9 Ensembl ENCODE 10.9 +59.1 59143 1.6 HDGF MTA2 EBF1 TBX21 EP300 RELA JUND IKZF1 HNF4G SPI1 C10orf11 MIR606 ENSG00000236842 ZNF503 ZNF503-AS2 GC10M075584 GC10P075624
GH10F075449 0.9 Ensembl ENCODE 10.5 -102.4 -102369 1.0 KLF1 KLF17 ZFHX2 ZBTB48 GLIS1 KLF9 PRDM1 EGR2 SP7 C10orf11 MIR606 ENSG00000279814 GC10P075451
GH10F075480 0.8 ENCODE 10.9 -71.7 -71655 1.0 SOX13 PKNOX1 SAP130 ZNF792 FEZF1 ZNF2 ZNF644 ZNF335 GATAD2A SOX5 C10orf11 MIR606 ZNF503 ZNF503-AS2 ENSG00000236842 GC10P075464 GC10P075560
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR606 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR606 Gene

Chromosome:
10
Start:
75,552,458 bp from pter
End:
75,552,553 bp from pter
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR606 Gene

Genes around MIR606 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR606 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR606 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR606 Gene

Proteins for MIR606 Gene

Post-translational modifications for MIR606 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR606 Gene

Domains & Families for MIR606 Gene

Gene Families for MIR606 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR606: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR606 Gene

Function for MIR606 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR606 Gene

Localization for MIR606 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR606 Gene

Pathways & Interactions for MIR606 Gene

SuperPathways for MIR606 Gene

No Data Available

Interacting Proteins for MIR606 Gene

Gene Ontology (GO) - Biological Process for MIR606 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR606 Gene

Transcripts for MIR606 Gene

mRNA/cDNA for MIR606 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR606 Gene

No ASD Table

Relevant External Links for MIR606 Gene

GeneLoc Exon Structure for
MIR606
ECgene alternative splicing isoforms for
MIR606

Expression for MIR606 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR606 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR606 Gene:

MIR606
genes like me logo Genes that share expression patterns with MIR606: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR606 Gene

Orthologs for MIR606 Gene

Evolution for MIR606 Gene

ENSEMBL:
Gene Tree for MIR606 (if available)
TreeFam:
Gene Tree for MIR606 (if available)

No data available for Orthologs for MIR606 Gene

Paralogs for MIR606 Gene

No data available for Paralogs for MIR606 Gene

Variants for MIR606 Gene

Sequence variations from dbSNP and Humsavar for MIR606 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs112349816 -- 75,551,737(+) AGAGG(-/AAA)CTAAA intron-variant, upstream-variant-2KB
rs117074006 -- 75,551,633(+) CCAGC(A/G)TCATG intron-variant, upstream-variant-2KB
rs117454538 -- 75,550,603(+) ATAAC(A/G)AGTCT intron-variant, upstream-variant-2KB
rs12266981 -- 75,552,342(+) atggt(A/G)tcact intron-variant, upstream-variant-2KB
rs1367290 -- 75,552,426(-) GGGGG(A/G)AAAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR606 Gene

Variant ID Type Subtype PubMed ID
esv2759768 CNV gain+loss 17122850
nsv1036391 CNV gain 25217958

Relevant External Links for MIR606 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR606

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR606 Gene

Disorders for MIR606 Gene

Relevant External Links for MIR606

Human Genome Epidemiology (HuGE) Navigator
MIR606
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR606

No disorders were found for MIR606 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR606 Gene

Publications for MIR606 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 64

Products for MIR606 Gene

Sources for MIR606 Gene

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