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Aliases for MIR604 Gene

Subcategory (RNA class) for MIR604 Gene


Quality Score for this RNA gene is


Aliases for MIR604 Gene

  • MicroRNA 604 2 3 5
  • Hsa-Mir-604 3
  • MIRN604 3

External Ids for MIR604 Gene

Previous HGNC Symbols for MIR604 Gene

  • MIRN604

Previous GeneCards Identifiers for MIR604 Gene

  • GC10M029874
  • GC10M029852

Summaries for MIR604 Gene

Entrez Gene Summary for MIR604 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR604 Gene

MIR604 (MicroRNA 604) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR604 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR604

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR604 Gene

Genomics for MIR604 Gene

Regulatory Elements for MIR604 Gene

Enhancers for MIR604 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F029522 1 Ensembl ENCODE 11.7 +22.5 22496 0.4 FEZF1 FOXP2 RAD21 MIR604 RNU6-908P GC10M029748 GC10P029496
GH10F029523 0.5 ENCODE 11.7 +22.1 22129 0.2 ZFP37 FEZF1 RAD21 ZNF101 ZNF692 ZNF366 ATF3 PRDM10 ZNF600 MAFK MIR604 RNU6-908P GC10M029748 GC10P029496
GH10F029574 0.6 Ensembl 11.6 -29.7 -29704 0.4 ZNF121 SREBF1 ZNF366 ZFP37 MIR604 GC10P029576 GC10M029739
GH10F029569 0.2 ENCODE 11.5 -25.2 -25232 1.4 CTCF RFX1 ZNF654 SIN3A FEZF1 ZNF843 RAD21 ZNF121 JUND GLIS1 SVIL MIR604 RNU6-908P GC10P029576 GC10M029739
GH10F029515 0.6 ENCODE 11.3 +28.5 28517 1.3 ZFHX2 ZNF687 ZNF341 MAFK EGR2 SVIL-AS1 MIR604 GC10M029748 GC10P029496
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR604 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR604 Gene

29,545,004 bp from pter
29,545,097 bp from pter
94 bases
Minus strand

Genomic View for MIR604 Gene

Genes around MIR604 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR604 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR604 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR604 Gene

ORGUL Member Location for MIR604 Gene

ORGUL Member Location for MIR604 gene

Proteins for MIR604 Gene

Post-translational modifications for MIR604 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR604 Gene

Domains & Families for MIR604 Gene

Gene Families for MIR604 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR604: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR604 Gene

Function for MIR604 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR604 Gene

Localization for MIR604 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR604 Gene

Pathways & Interactions for MIR604 Gene

SuperPathways for MIR604 Gene

No Data Available

Interacting Proteins for MIR604 Gene

Gene Ontology (GO) - Biological Process for MIR604 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR604 Gene

Transcripts for MIR604 Gene

fRNAdb Secondary structures for MIR604 Gene

  • hsa-mir-604_MI0003617_Homo_sapiens_miR-604_stem-loop_hairpin

mRNA/cDNA for MIR604 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR604 Gene

No ASD Table

Relevant External Links for MIR604 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR604 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR604 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR604 Gene:

genes like me logo Genes that share expression patterns with MIR604: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR604 Gene

Orthologs for MIR604 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR604 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-604 35
  • 97 (a)
Species where no ortholog for MIR604 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR604 Gene

Gene Tree for MIR604 (if available)
Gene Tree for MIR604 (if available)

Paralogs for MIR604 Gene

No data available for Paralogs for MIR604 Gene

Variants for MIR604 Gene

Sequence variations from dbSNP and Humsavar for MIR604 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs11374844 -- 29,546,574(+) AATGC(-/T)TAATG intron-variant, upstream-variant-2KB
rs115181305 -- 29,546,993(+) GTTTT(C/T)GGTTA intron-variant, upstream-variant-2KB
rs11592360 -- 29,544,708(+) AGATT(A/G)TGCTA intron-variant, downstream-variant-500B
rs11594466 -- 29,545,871(+) aaaaa(A/G)aaaaa intron-variant, upstream-variant-2KB
rs115984990 -- 29,546,409(+) CCTGG(A/G)CATCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR604 Gene

Variant ID Type Subtype PubMed ID
nsv1038080 CNV gain 25217958
nsv1129323 OTHER inversion 24896259
nsv831819 CNV loss 17160897

Relevant External Links for MIR604 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR604 Gene

Disorders for MIR604 Gene

Relevant External Links for MIR604

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR604 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR604 Gene

Publications for MIR604 Gene

  1. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 46 64
  2. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J. … Wu X. (Carcinogenesis 2010) 3 46 64
  3. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y. … Wu X. (Cancer Prev Res (Phila) 2008) 3 46 64
  4. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3 64
  5. Association of Polymorphism in MicroRNA 604 with Susceptibility to Persistent Hepatitis B Virus Infection and Development of Hepatocellular Carcinoma. (PMID: 25408584) Cheong J.Y. … Kim Y.J. (J. Korean Med. Sci. 2014) 3 64

Products for MIR604 Gene

Sources for MIR604 Gene

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