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Aliases for MIR603 Gene

Subcategory (RNA class) for MIR603 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR603 Gene

  • MicroRNA 603 2 3
  • Hsa-Mir-603 3
  • MIRN603 3

External Ids for MIR603 Gene

ORGUL Members for MIR603 Gene

Previous Symbols for MIR603 Gene

  • MIRN603

Summaries for MIR603 Gene

Entrez Gene Summary for MIR603 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR603 Gene

MIR603 (MicroRNA 603) is an RNA Gene, and belongs to the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR603 Gene

Genomics for MIR603 Gene

Genomic Location for MIR603 Gene

Start:
24,275,685 bp from pter
End:
24,275,781 bp from pter
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR603 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR603 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR603 Gene

No data available for Regulatory Elements for MIR603 Gene

Proteins for MIR603 Gene

Post-translational modifications for MIR603 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR603 Gene

Domains for MIR603 Gene

Gene Families for MIR603 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR603: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR603 Gene

Function for MIR603 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR603 Gene

Localization for MIR603 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR603 Gene

Pathways for MIR603 Gene

SuperPathways for MIR603 Gene

No Data Available

Interacting Proteins for MIR603 Gene

Gene Ontology (GO) - Biological Process for MIR603 Gene

None

No data available for Pathways by source for MIR603 Gene

Transcripts for MIR603 Gene

mRNA/cDNA for MIR603 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR603 Gene

No ASD Table

Relevant External Links for MIR603 Gene

GeneLoc Exon Structure for
MIR603
ECgene alternative splicing isoforms for
MIR603

Expression for MIR603 Gene

mRNA expression in normal human tissues for MIR603 Gene

genes like me logo Genes that share expressions with MIR603: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR603 Gene

Orthologs for MIR603 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR603 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
OneToOne
Species with no ortholog for MIR603:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR603 Gene

ENSEMBL:
Gene Tree for MIR603 (if available)
TreeFam:
Gene Tree for MIR603 (if available)

Paralogs for MIR603 Gene

No data available for Paralogs for MIR603 Gene

Variants for MIR603 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR603 Gene

Variant ID Type Subtype PubMed ID
nsv520378 CNV Loss 19592680

Relevant External Links for MIR603 Gene

HapMap Linkage Disequilibrium report
MIR603

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR603 Gene

Disorders for MIR603 Gene

No disorders were found for MIR603 Gene.

No data available for UniProtKB/Swiss-Prot for MIR603 Gene

Publications for MIR603 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. MicroRNA alterations of pancreatic intraepithelial neoplasias. (PMID: 22114139) Yu J. … Goggins M. (Clin. Cancer Res. 2012) 3
  4. Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1. (PMID: 22564666) D'Angelo D. … Fusco A. (J. Clin. Endocrinol. Metab. 2012) 3
  5. The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression. (PMID: 23384558) Mussnich P. … Fusco A. (Mol Oncol 2013) 3

Products for MIR603 Gene

Sources for MIR603 Gene

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