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Aliasesfor MIR602 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section GeneCards Plus Subcategory (RNA class): miRNAQuality score for this RNA gene is 3 Aliases MicroRNA 602 1 2 MIRN6021 2 hsa-mir-6022 mir-6029
External Ids: HGNC: 32858 1 Entrez Gene: 693187 2 Ensembl: ENSG00000207693 7 Export aliases for MIR602 gene to outside databases Previous GC identifer: GC09P139853
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Summariesfor MIR602 gene (According to Entrez Gene ,
GeneCards ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section GeneCards Plus Entrez Gene summary for MIR602 Gene: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation ofgene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs aretranscribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that canbe either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzymeto produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by thecytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. Themature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs throughimperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization ofthe target mRNA. The RefSeq represents the predicted microRNA stem-loop. (provided by RefSeq, Sep 2009) GeneCards Summary for MIR602 Gene: MIR602 (microRNA 602) is an RNA gene, and is affiliated with the miRNA class. Diseases associated with MIR602 include noma hepatitis b virus infection
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Genomic Viewsfor MIR602 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 75) ,
Regulatory elements and Epigenetics data according to
QIAGEN , and/or
SwitchGear Genomics )About This Section GeneCards Plus Regulatory elements: Search for regulatory transcription factor binding sites for MIR602 Other transcription factors Search Chromatin IP Primers for MIR602 Epigenetics: DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MIR602
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 9q34.3 Ensembl cytogenetic band: 9q34.3 HGNC cytogenetic band: 9q34.3 MIR602 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 9 GeneLoc Exon Structure
GeneLoc location for GC09P140732: view genomic region miRBase )
(about GC identifiers )
Start: 140,732,871 bp from pter End:
140,732,968 bp from pter
Size: 98 bases Orientation:
plus strand
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Proteinsfor MIR602 gene
(According to
1 UniProtKB ,
HORDE ,
2 neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Antibodies by
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section GeneCards Plus UniProtKB: --
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Domains /for MIR602 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section GeneCards Plus HGNC Gene Families: MIR: ncRNAs / Micro RNAs
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Functionfor MIR602 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
genOway ,
QIAGEN
and/or HOMER ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
Gene Editing from DNA2.0 ,
Clones from OriGene ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
ESI BIO ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus Animal Models: Cell Line GenScript Custom overexpressing Cell Line Services for MIR602 Browse ESI BIO Cell Lines and PureStem Progenitors for MIR602 In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR602
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Localizationfor MIR602 gene
(According to UniProtKB , COMPARTMENTS Subcellular localization database ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus
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Pathways & Interactionsfor MIR602 gene
(SuperPaths according to PathCards ,
Pathways according to
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
QIAGEN ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene) .
About This Section GeneCards Plus
SuperPaths for MIR602 About See pathways by source Pathways by source See SuperPaths Show all pathways 1 (Kegg details for MIR602) :About GeneDecksing Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MIR602 Interactions: Search GeneGlobe Interaction Network for MIR602
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Drugs & Compoundsfor MIR602 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience ,
ApexBio ,
HMDB ,
BitterDB , and/or
Novoseek ,
Ligands according to IUPHAR ,
and Drugs according to DrugBank ,
Enzo Life Sciences , and/or
PharmGKB )
About This Section GeneCards Plus
Browse compounds at ApexBio Browse Tocris compounds for MIR602
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Transcriptsfor MIR602 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
OriGene ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene , and/or
QIAGEN
)About This Section GeneCards Plus 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000384960(miRNA) GeneLoc Exon Structure
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Expression for MIR602 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MaxQB ,
plus additional links to
SOURCE , and/or
BioGPS , and/or
UniProtKB ,QIAGEN ,
Primers from
OriGene , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GeneCards Plus
Expression evidence for MIR602:none See probesets specificity/sensitivity at GeneAnnot CGAP TAG: --
MIR602 Protein expression data from MOPED1 2 3 : Custom PCR Arrays for MIR602 Primer Browse OriGene qPCR Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat MIR602 Search QuantiTect SYBR Green Assays in human, mouse, rat MIR602 Search QuantiFast Probe-based Assays in human, mouse, rat MIR602 In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR602
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Orthologsfor MIR602 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section GeneCards Plus
ENSEMBL Gene Tree for MIR602 (if available)TreeFam Gene Tree for MIR602 (if available)
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Paralogsfor MIR602 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section GeneCards Plus
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Genomic Variantsfor MIR602 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) , the Human Cytochrome P450 Allele
Nomenclature Database , and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN )
About This Section GeneCards Plus Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 9 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for MIR602 (140732871 - 140732968 bp)
Structural Variations Database of Genomic Variants (DGV) 4 variations for MIR602 : About this table Site Specific Mutation Identification with PCR Assays
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Disorders
/ Diseasesfor MIR602 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section GeneCards Plus
5 : About MalaCards noma hepatitis b virus infection hepatitis b hepatitis hepatocellular carcinoma About GeneDecksing Export disorders for MIR602 gene to outside databases
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Publicationsfor MIR602 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section GeneCards Plus PubMed articles for MIR602 gene integrated from 10 sources :(articles sorted by number of sources associating them with MIR602) Utopia : connect your pdf to the dynamic
MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma. (PubMed id 20364114) 1 (amp 2010) miRBase: microRNA sequences, targets and gene nomenclature. (PubMed id 16381832) 1 (Nucleic Acids Res. 2006) The colorectal microRNAome. (PubMed id 16505370) 1 (Proc. Natl. Acad. Sci. U.S.A. 2006)
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External Searches for MIR602 gene (in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section GeneCards Plus
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Genome Databases showing MIR602 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section GeneCards Plus
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Other Databases showing MIR602 gene
(According to HUGE )
About This Section GeneCards Plus --
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Specialized Databases showing MIR602 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , UniProtKB/TrEMBL , and/or others, e.g. Wikipedia and GeneReviews , via UniProtKB/Swiss-Prot )About This Section GeneCards Plus
Name Description PharmGKB entry for MIR602 Pharmacogenomics, SNPs, Pathways
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About This Section GeneCards Plus Patent Information for MIR602 gene: MIR602 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor MIR602 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 . Clones from OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , and ESI BIO , PCR Arrays from QIAGEN , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , Enzo Life Sciences , and/or
ApexBio , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory ,
genOway )About This Section GeneCards Plus
Block miRNA regulation of human, mouse, rat MIR602 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MIR602 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MIR602 Predesigned siRNA for gene silencing in human mouse rat Search QuantiFast Probe-based Assays in human, mouse, rat MIR602 Search QuantiTect SYBR Green Assays in human, mouse, rat MIR602 Custom PCR Arrays for MIR602 Search Chromatin IP Primers for MIR602 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MIR602 Search GeneGlobe Interaction Network for MIR602 Search Regulatory tfbs for MIR602
Search Tocris compounds for MIR602
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR602
Search ThermoFisher Antibodies for MIR602
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MIR602
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