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Aliases for MIR602 Gene

Subcategory (RNA class) for MIR602 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR602 Gene

  • MicroRNA 602 2 3 5
  • Hsa-Mir-602 3
  • MIRN602 3

External Ids for MIR602 Gene

ORGUL Members for MIR602 Gene

Previous HGNC Symbols for MIR602 Gene

  • MIRN602

Previous GeneCards Identifiers for MIR602 Gene

  • GC09P139853
  • GC09P140732

Summaries for MIR602 Gene

Entrez Gene Summary for MIR602 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR602 Gene

MIR602 (MicroRNA 602) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR602 Gene

Genomics for MIR602 Gene

Regulatory Elements for MIR602 Gene

Enhancers for MIR602 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR602 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR602 Gene

Chromosome:
9
Start:
137,838,419 bp from pter
End:
137,838,516 bp from pter
Size:
98 bases
Orientation:
Plus strand

Genomic View for MIR602 Gene

Genes around MIR602 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR602 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR602 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR602 Gene

Proteins for MIR602 Gene

Post-translational modifications for MIR602 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR602 Gene

Domains & Families for MIR602 Gene

Gene Families for MIR602 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR602: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR602 Gene

Function for MIR602 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR602 Gene

Localization for MIR602 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR602 Gene

Pathways & Interactions for MIR602 Gene

SuperPathways for MIR602 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR602: view

Pathways by source for MIR602 Gene

1 KEGG pathway for MIR602 Gene

Interacting Proteins for MIR602 Gene

Gene Ontology (GO) - Biological Process for MIR602 Gene

None

No data available for SIGNOR curated interactions for MIR602 Gene

Drugs & Compounds for MIR602 Gene

No Compound Related Data Available

Transcripts for MIR602 Gene

mRNA/cDNA for MIR602 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR602 Gene

No ASD Table

Relevant External Links for MIR602 Gene

GeneLoc Exon Structure for
MIR602
ECgene alternative splicing isoforms for
MIR602

Expression for MIR602 Gene

mRNA expression in normal human tissues for MIR602 Gene

genes like me logo Genes that share expression patterns with MIR602: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR602 Gene

Orthologs for MIR602 Gene

Evolution for MIR602 Gene

ENSEMBL:
Gene Tree for MIR602 (if available)
TreeFam:
Gene Tree for MIR602 (if available)

No data available for Orthologs for MIR602 Gene

Paralogs for MIR602 Gene

No data available for Paralogs for MIR602 Gene

Variants for MIR602 Gene

Sequence variations from dbSNP and Humsavar for MIR602 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs113378249 -- 137,838,118(+) GCCTC(C/T)GGCCA upstream-variant-2KB
rs115144732 -- 137,837,559(+) AGGTG(C/T)GGGGA upstream-variant-2KB
rs115368575 -- 137,836,860(+) CCAGG(A/G)TGGAT upstream-variant-2KB
rs9410050 -- 137,836,939(+) CCTAC(A/G)GCCTT upstream-variant-2KB
rs116636751 -- 137,838,511(+) GAGCC(C/T)CCCTG nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR602 Gene

Variant ID Type Subtype PubMed ID
dgv8412n71 CNV Loss 21882294
nsv894676 CNV Loss 21882294
nsv894678 CNV Loss 21882294
nsv825197 CNV Gain 20364138

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR602 Gene

Disorders for MIR602 Gene

Relevant External Links for MIR602

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR602

No disorders were found for MIR602 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR602 Gene

Publications for MIR602 Gene

  1. MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. (PMID: 25385442) Akhtar N. … Haqqi T.M. ( 2015) 3 67
  2. MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma. (PMID: 20364114) Yang L. … Wang G. (Cancer Biol. Ther. 2010) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for MIR602 Gene

Sources for MIR602 Gene

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