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MIR602 Gene(RNA Gene)

MicroRNA 602

GCID:
GC09P137838
GIFtS:
15
Genes Participants
UDN Logo

Aliases for MIR602 Gene

Subcategory (RNA class) for MIR602 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR602 Gene

  • MicroRNA 602 2 3 5
  • Hsa-Mir-602 3
  • MIRN602 3

External Ids for MIR602 Gene

ORGUL Members for MIR602 Gene

Previous HGNC Symbols for MIR602 Gene

  • MIRN602

Previous GeneCards Identifiers for MIR602 Gene

  • GC09P139853
  • GC09P140732

Summaries for MIR602 Gene

Entrez Gene Summary for MIR602 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR602 Gene

MIR602 (MicroRNA 602) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR602 include Deafness, Autosomal Recessive 79 and Deafness, Autosomal Recessive 33. Among its related pathways are MicroRNAs in cancer.

Additional gene information for MIR602 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR602 Gene

Genomics for MIR602 Gene

Products:

  1. Regulatory Element

Genomic Locations for MIR602 Gene

Genomic Locations for MIR602 Gene
chr9:137,838,419-137,838,516
(GRCh38/hg38)
Size:
98 bases
Orientation:
Plus strand
chr9:140,732,871-140,732,968
(GRCh37/hg19)

Genomic View for MIR602 Gene

Genes around MIR602 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR602 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR602 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR602 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR602 Gene

Proteins for MIR602 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR602 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR602 Gene

Domains & Families for MIR602 Gene

Gene Families for MIR602 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR602: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR602 Gene

Function for MIR602 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR602 Gene

Localization for MIR602 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR602 Gene

Pathways & Interactions for MIR602 Gene

SuperPathways for MIR602 Gene

PathCards logo More details on SuperPathways for MIR602
SuperPathway Contained pathways
1 MicroRNAs in cancer
MicroRNAs in cancer
-
genes like me logo Genes that share pathways with MIR602: view

Pathways by source for MIR602 Gene

1 KEGG pathway for MIR602 Gene

Interacting Proteins for MIR602 Gene

Gene Ontology (GO) - Biological Process for MIR602 Gene

None

No data available for SIGNOR curated interactions for MIR602 Gene

Drugs & Compounds for MIR602 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR602 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR602 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR602 Gene

No ASD Table

Relevant External Links for MIR602 Gene

GeneLoc Exon Structure for
MIR602
ECgene alternative splicing isoforms for
MIR602

Expression for MIR602 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR602 Gene

mRNA expression in normal human tissues for MIR602 Gene
mRNA expression by GTEx for MIR602 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR602 Gene:

MIR602
genes like me logo Genes that share expression patterns with MIR602: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR602 Gene

Orthologs for MIR602 Gene

Evolution for MIR602 Gene

ENSEMBL:
Gene Tree for MIR602 (if available)
TreeFam:
Gene Tree for MIR602 (if available)

No data available for Orthologs for MIR602 Gene

Paralogs for MIR602 Gene

No data available for Paralogs for MIR602 Gene

Variants for MIR602 Gene

Sequence variations from dbSNP and Humsavar for MIR602 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000452184 -- 137,836,714(+) T/C upstream_transcript_variant
rs1002338391 -- 137,838,967(+) C/A downstream_transcript_variant
rs1002597092 -- 137,837,066(+) G/A upstream_transcript_variant
rs1002648071 -- 137,836,912(+) A/G upstream_transcript_variant
rs1003606433 -- 137,837,984(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR602 Gene

Variant ID Type Subtype PubMed ID
nsv825197 CNV gain 20364138
nsv951213 CNV deletion 24416366

Additional Variant Information for MIR602 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR602

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR602 Gene

Disorders for MIR602 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR602 Gene - From: DISEASES

Disorder Aliases PubMed IDs
deafness, autosomal recessive 79
  • dfnb79
deafness, autosomal recessive 33
  • dfnb33
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR602

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with MIR602: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR602 Gene

Publications for MIR602 Gene

  1. MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. (PMID: 25385442) Akhtar N … Haqqi TM (Arthritis & rheumatology (Hoboken, N.J.) 2015) 3 58
  2. MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma. (PMID: 20364114) Yang L … Wang G (Cancer biology & therapy 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  4. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 58

Products for MIR602 Gene

Sources for MIR602 Gene

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