Aliases for MIR602 Gene
Subcategory (RNA class) for MIR602 Gene
Quality Score for this RNA gene is
External Ids for MIR602 Gene
- HGNC: 32858
- Entrez Gene: 693187
- Ensembl: ENSG00000207693
- miRBase: hsa-mir-602
Previous HGNC Symbols for MIR602 Gene
- MIRN602
Previous GeneCards Identifiers for MIR602 Gene
- GC09P139853
- GC09P140732
Summaries for MIR602 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR602 Gene
MIR602 (MicroRNA 602) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR602 include Deafness, Autosomal Recessive 79 and Deafness, Autosomal Recessive 33. Among its related pathways are MicroRNAs in cancer.
Additional gene information for MIR602 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR602 Gene
Genomics for MIR602 Gene
Regulatory Element Products
Genomic Locations for MIR602 Gene
- chr9:137,838,419-137,838,516
- (GRCh38/hg38)
- Size:
- 98 bases
- Orientation:
- Plus strand
- chr9:140,732,871-140,732,968
- (GRCh37/hg19)
Genomic View for MIR602 Gene
- Cytogenetic band:
-
- 9q34.3 by Ensembl
- 9q34.3 by Entrez Gene
- 9q34.3 by HGNC


RefSeq DNA sequence for MIR602 Gene
No data available for GeneHancer (GH) Regulatory Elements for MIR602 Gene
Proteins for MIR602 Gene
Post-translational modifications for MIR602 Gene
Antibody Products
- Search GeneTex for Antibodies for MIR602
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR602
- Origene Custom Protein Services for MIR602
- Search GeneTex for Proteins for MIR602
No data available for DME Specific Peptides for MIR602 Gene
Domains & Families for MIR602 Gene
Gene Families for MIR602 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR602 Gene
Function for MIR602 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR602
-
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CRISPR Products
- Browse CRISPR knockouts for MIR602
- Applied Biological Materials CRISPR for MIR602
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR602
Clone Products
- GenScript: Custom all cDNA clones Services for MIR602
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR602
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR602 Gene
Localization for MIR602 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR602 Gene
Pathways & Interactions for MIR602 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | MicroRNAs in cancer |
Pathways by source for MIR602 Gene
1 KEGG pathway for MIR602 Gene
Interacting Proteins for MIR602 Gene
No data available for SIGNOR curated interactions for MIR602 Gene
Transcripts for MIR602 Gene
mRNA/cDNA for MIR602 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR602
- Applied Biological Materials CRISPR for MIR602
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR602
Clone Products
- GenScript: Custom all cDNA clones Services for MIR602
- VectorBuilder custom plasmid, inducible vectors for MIR602
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR602
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR602
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR602 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR602 Gene:
MIR602Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR602 Gene
Orthologs for MIR602 Gene
No data available for Orthologs for MIR602 Gene
Paralogs for MIR602 Gene
No data available for Paralogs for MIR602 Gene
Variants for MIR602 Gene
SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000452184 | -- | 137,836,714(+) | T/C | upstream_transcript_variant | |
rs1002338391 | -- | 137,838,967(+) | C/A | downstream_transcript_variant | |
rs1002597092 | -- | 137,837,066(+) | G/A | upstream_transcript_variant | |
rs1002648071 | -- | 137,836,912(+) | A/G | upstream_transcript_variant | |
rs1003606433 | -- | 137,837,984(+) | G/A | upstream_transcript_variant |
Additional Variant Information for MIR602 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR602
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR602 Gene
Disorders for MIR602 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
deafness, autosomal recessive 79 |
|
|
deafness, autosomal recessive 33 |
|
|
Additional Disease Information for MIR602
No data available for UniProtKB/Swiss-Prot and Genatlas for MIR602 Gene
Publications for MIR602 Gene
- MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. (PMID: 25385442) Akhtar N … Haqqi TM (Arthritis & rheumatology (Hoboken, N.J.) 2015) 3 58
- MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma. (PMID: 20364114) Yang L … Wang G (Cancer biology & therapy 2010) 3 58
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
- The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 58
Products for MIR602 Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR602
- VectorBuilder custom plasmid, inducible vectors for MIR602
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR602
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR602
- Search GeneTex for Proteins for MIR602
Sources for MIR602 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
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- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew