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Aliases for MIR600 Gene

Subcategory (RNA class) for MIR600 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR600 Gene

  • MicroRNA 600 2 3 5
  • Hsa-Mir-600 3
  • MIRN600 3

External Ids for MIR600 Gene

Previous HGNC Symbols for MIR600 Gene

  • MIRN600

Previous GeneCards Identifiers for MIR600 Gene

  • GC09M124914
  • GC09M125873

Summaries for MIR600 Gene

Entrez Gene Summary for MIR600 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR600 Gene

MIR600 (MicroRNA 600) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR600 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR600

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR600 Gene

Genomics for MIR600 Gene

Regulatory Elements for MIR600 Gene

Enhancers for MIR600 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G123355 1.5 Ensembl ENCODE dbSUPER 10.8 -246.9 -246878 6.2 HDGF ATF1 MLX CREB3L1 ZFP64 ARID4B ZNF48 TCF12 GLIS2 CBX5 STRBP MIR601 DENND1A MIR600HG MIR600 CRB2 GC09P123401
GH09G123304 1.5 Ensembl ENCODE dbSUPER 10.7 -193.3 -193265 1.3 PKNOX1 ATF1 ARNT ZNF48 TCF12 ZNF766 GLIS2 ELK1 GATA2 KLF7 ZBTB26 STRBP MIR600HG MIR600 GC09M123300 LOC105376265
GH09G123048 1.5 FANTOM5 Ensembl ENCODE dbSUPER 10.4 +62.2 62236 2.2 GTF2F1 FEZF1 ARID3A NCOR1 ZBTB48 ZSCAN5C HNF4G CREM STAT1 MTA2 MIR600 MIR600HG RABGAP1 LOC100422501 GPR21
GH09G123364 1.2 FANTOM5 ENCODE dbSUPER 10.8 -252.9 -252896 0.7 TFAP4 MAZ NFIB BHLHE40 ZNF398 ZBTB7A HIC1 ZFHX2 JUND ZNF157 MIR601 DENND1A MIR600 MIR600HG STRBP CRB2 GC09P123401
GH09G123302 1.1 ENCODE dbSUPER 10.7 -191.2 -191238 1.1 HDAC1 HDGF TBL1XR1 ZBTB40 TCF12 ZNF766 GATA2 EGR1 ELF4 NCOA1 STRBP MIR600HG MIR600 GC09M123300 LOC105376265
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR600 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR600 Gene

Chromosome:
9
Start:
123,111,546 bp from pter
End:
123,111,643 bp from pter
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR600 Gene

Genes around MIR600 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR600 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR600 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR600 Gene

ORGUL Member Location for MIR600 Gene

ORGUL Member Location for MIR600 gene

Proteins for MIR600 Gene

Post-translational modifications for MIR600 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR600 Gene

Domains & Families for MIR600 Gene

Gene Families for MIR600 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR600: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR600 Gene

Function for MIR600 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR600 Gene

Localization for MIR600 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR600 Gene

Pathways & Interactions for MIR600 Gene

SuperPathways for MIR600 Gene

No Data Available

Interacting Proteins for MIR600 Gene

Gene Ontology (GO) - Biological Process for MIR600 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR600 Gene

Drugs & Compounds for MIR600 Gene

No Compound Related Data Available

Transcripts for MIR600 Gene

fRNAdb Secondary structures for MIR600 Gene

  • FR345552
  • hsa-mir-600_MI0003613_Homo_sapiens_miR-600_stem-loop_hairpin

mRNA/cDNA for MIR600 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR600 Gene

No ASD Table

Relevant External Links for MIR600 Gene

GeneLoc Exon Structure for
MIR600
ECgene alternative splicing isoforms for
MIR600

Expression for MIR600 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR600 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR600 Gene:

MIR600
genes like me logo Genes that share expression patterns with MIR600: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR600 Gene

Orthologs for MIR600 Gene

Evolution for MIR600 Gene

ENSEMBL:
Gene Tree for MIR600 (if available)
TreeFam:
Gene Tree for MIR600 (if available)

No data available for Orthologs for MIR600 Gene

Paralogs for MIR600 Gene

No data available for Paralogs for MIR600 Gene

Variants for MIR600 Gene

Sequence variations from dbSNP and Humsavar for MIR600 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1001066922 -- 123,113,585(+) AAAAC(C/T)TAAGT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1001136641 -- 123,113,377(+) CATCC(A/G)TTATC intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1003528000 -- 123,112,388(+) GCCAT(C/T)TTTCT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1003601858 -- 123,112,217(+) GTCCC(A/G)CCTCG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1004536692 -- 123,113,293(+) TGAGC(C/T)TGGCC intron-variant, nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR600 Gene

Variant ID Type Subtype PubMed ID
nsv831717 CNV gain 17160897

Relevant External Links for MIR600 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR600

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR600 Gene

Disorders for MIR600 Gene

Relevant External Links for MIR600

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR600

No disorders were found for MIR600 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR600 Gene

Publications for MIR600 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR600 Gene

Sources for MIR600 Gene

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