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Aliases for MIR596 Gene

Subcategory (RNA class) for MIR596 Gene


Quality Score for this RNA gene is


Aliases for MIR596 Gene

  • MicroRNA 596 2 3 5
  • Hsa-Mir-596 3
  • MIRN596 3

External Ids for MIR596 Gene

Previous HGNC Symbols for MIR596 Gene

  • MIRN596

Previous GeneCards Identifiers for MIR596 Gene

  • GC08P001754
  • GC08P001765

Summaries for MIR596 Gene

Entrez Gene Summary for MIR596 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR596 Gene

MIR596 (MicroRNA 596) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR596 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR596 Gene

Genomics for MIR596 Gene

Regulatory Elements for MIR596 Gene

Enhancers for MIR596 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H001785 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12.7 -29.7 -29734 3.8 KLF1 JUN RFX5 FOSL1 HIC1 GLIS2 ZNF366 RCOR1 FOS STAT1 ENSG00000253982 CLN8 MIR596 PIR39323 MIR3674
GH08H001889 0.7 FANTOM5 dbSUPER 11.4 +72.6 72614 0.4 GLIS2 GLIS1 MIR596 GC08P001908 ARHGEF10
GH08H001854 0.4 ENCODE 11.9 +38.5 38500 2.6 CEBPB MIR596 ARHGEF10 GC08P001908
GH08H001888 0.3 FANTOM5 11.4 +71.6 71593 0.3 MIR596 KBTBD11 GC08P001908 ARHGEF10
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR596 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR596 Gene

Genomic Locations for MIR596 Gene
77 bases
Plus strand

Genomic View for MIR596 Gene

Genes around MIR596 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR596 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR596 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR596 Gene

Proteins for MIR596 Gene

Post-translational modifications for MIR596 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR596 Gene

Domains & Families for MIR596 Gene

Gene Families for MIR596 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR596: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR596 Gene

Function for MIR596 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR596 Gene

Localization for MIR596 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR596 Gene

Pathways & Interactions for MIR596 Gene

SuperPathways for MIR596 Gene

No Data Available

Interacting Proteins for MIR596 Gene

Gene Ontology (GO) - Biological Process for MIR596 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR596 Gene

Drugs & Compounds for MIR596 Gene

No Compound Related Data Available

Transcripts for MIR596 Gene

mRNA/cDNA for MIR596 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR596 Gene

No ASD Table

Relevant External Links for MIR596 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR596 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR596 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR596 Gene:

genes like me logo Genes that share expression patterns with MIR596: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR596 Gene

Orthologs for MIR596 Gene

Evolution for MIR596 Gene

Gene Tree for MIR596 (if available)
Gene Tree for MIR596 (if available)

No data available for Orthologs for MIR596 Gene

Paralogs for MIR596 Gene

No data available for Paralogs for MIR596 Gene

Variants for MIR596 Gene

Sequence variations from dbSNP and Humsavar for MIR596 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000146753 -- 1,816,835(+) ATGCA(A/C)CGTCC upstream-variant-2KB
rs1001303252 -- 1,816,241(+) CTAAC(C/G)AGACG upstream-variant-2KB
rs1002216360 -- 1,815,505(+) GGCTC(A/C)TGCCT upstream-variant-2KB
rs1002920825 -- 1,815,306(+) TGCTA(A/G)AAAGG upstream-variant-2KB
rs1005501411 -- 1,815,364(+) CCTTT(C/T)TGTAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR596 Gene

Variant ID Type Subtype PubMed ID
nsv824454 CNV gain 20364138
nsv609533 CNV gain 21841781
nsv609531 CNV gain 21841781
nsv509244 CNV insertion 20534489
nsv470167 CNV gain 18288195
nsv465277 CNV gain 19166990
nsv1025591 CNV gain 25217958
nsv1024325 CNV gain 25217958
nsv1017597 CNV loss 25217958
esv3891267 CNV gain 25118596
esv3615842 CNV gain 21293372
esv3615841 CNV loss 21293372
esv3576504 CNV gain 25503493
dgv850n27 CNV loss 19166990
dgv11822n54 CNV loss 21841781

Relevant External Links for MIR596 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR596 Gene

Disorders for MIR596 Gene

Relevant External Links for MIR596

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR596 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR596 Gene

Publications for MIR596 Gene

  1. Exploration of Alternative Mechanism for MiR-596-mediated Down-regulation of LGALS3BP in Oral Squamous Cell Carcinoma. (PMID: 26502662) Li H (Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan 2015) 3 60
  2. Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer. (PMID: 23233740) Endo H … Kozaki K (Carcinogenesis 2013) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60
  4. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 60

Products for MIR596 Gene

Sources for MIR596 Gene

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