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Aliases for MIR596 Gene

Subcategory (RNA class) for MIR596 Gene


Quality Score for this RNA gene is


Aliases for MIR596 Gene

  • MicroRNA 596 2 3
  • Hsa-Mir-596 3
  • MIRN596 3

External Ids for MIR596 Gene

ORGUL Members for MIR596 Gene

Previous HGNC Symbols for MIR596 Gene

  • MIRN596

Previous GeneCards Identifiers for MIR596 Gene

  • GC08P001754
  • GC08P001765

Summaries for MIR596 Gene

Entrez Gene Summary for MIR596 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR596 Gene

MIR596 (MicroRNA 596) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR596 Gene

Genomics for MIR596 Gene

Genomic Location for MIR596 Gene

1,817,231 bp from pter
1,817,307 bp from pter
77 bases
Plus strand

Genomic View for MIR596 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR596 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR596 Gene

No data available for Regulatory Elements for MIR596 Gene

Proteins for MIR596 Gene

Post-translational modifications for MIR596 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR596 Gene

Domains for MIR596 Gene

Gene Families for MIR596 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR596: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR596 Gene

Function for MIR596 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR596 Gene

Localization for MIR596 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR596 Gene

Pathways for MIR596 Gene

SuperPathways for MIR596 Gene

No Data Available

Interacting Proteins for MIR596 Gene

Gene Ontology (GO) - Biological Process for MIR596 Gene


No data available for Pathways by source for MIR596 Gene

Transcripts for MIR596 Gene

mRNA/cDNA for MIR596 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR596 Gene

No ASD Table

Relevant External Links for MIR596 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR596 Gene

mRNA expression in normal human tissues for MIR596 Gene

genes like me logo Genes that share expressions with MIR596: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR596 Gene

Orthologs for MIR596 Gene

Evolution for MIR596 Gene

Gene Tree for MIR596 (if available)
Gene Tree for MIR596 (if available)

No data available for Orthologs for MIR596 Gene

Paralogs for MIR596 Gene

No data available for Paralogs for MIR596 Gene

Variants for MIR596 Gene

Sequence variations from dbSNP and Humsavar for MIR596 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1123543 -- 1,817,406(+) AGACA(A/C)ACTCA downstream-variant-500B
rs6558547 -- 1,817,554(+) TCCTG(A/G)AGGGC downstream-variant-500B
rs6558548 -- 1,817,732(+) GCAGG(A/G)CGCGG downstream-variant-500B
rs6980781 -- 1,817,205(+) AGGTG(A/G)ATCCG upstream-variant-2KB
rs10713557 -- 1,816,778(+) AGAGC(-/G)GGGGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR596 Gene

Variant ID Type Subtype PubMed ID
nsv889697 CNV Gain 21882294
dgv7588n71 CNV Gain 21882294
dgv7590n71 CNV Gain 21882294
nsv889712 CNV Gain 21882294
dgv850n27 CNV Loss 19166990
nsv509244 CNV Insertion 20534489
nsv824454 CNV Gain 20364138
nsv470167 CNV Gain 18288195
nsv465277 CNV Gain 19166990
dgv7592n71 CNV Gain 21882294
dgv7593n71 CNV Loss 21882294
dgv7594n71 CNV Loss 21882294
nsv889724 CNV Gain 21882294
dgv7595n71 CNV Loss 21882294

Relevant External Links for MIR596 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR596 Gene

Disorders for MIR596 Gene

No disorders were found for MIR596 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR596 Gene

Publications for MIR596 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer. (PMID: 23233740) Endo H. … Kozaki K. (Carcinogenesis 2013) 3

Products for MIR596 Gene

Sources for MIR596 Gene

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