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Aliases for MIR596 Gene

Subcategory (RNA class) for MIR596 Gene


Quality Score for this RNA gene is


Aliases for MIR596 Gene

  • MicroRNA 596 2 3 5
  • Hsa-Mir-596 3
  • MIRN596 3

External Ids for MIR596 Gene

Previous HGNC Symbols for MIR596 Gene

  • MIRN596

Previous GeneCards Identifiers for MIR596 Gene

  • GC08P001754
  • GC08P001765

Summaries for MIR596 Gene

Entrez Gene Summary for MIR596 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR596 Gene

MIR596 (MicroRNA 596) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR596 Gene

Genomics for MIR596 Gene

Regulatory Elements for MIR596 Gene

Enhancers for MIR596 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F001785 1.5 FANTOM5 Ensembl ENCODE 12.7 -29.7 -29731 4.2 PKNOX1 TBL1XR1 ZNF2 RAD21 RFX5 GLIS2 ZNF366 ZNF143 RCOR1 FOS ENSG00000253982 CLN8 MIR596 PIR39323 LOC105377779
GH08F001854 0.9 Ensembl ENCODE 11.9 +38.5 38500 2.6 REST MIR596 ARHGEF10 GC08P001908
GH08F001888 0.7 FANTOM5 11.3 +71.6 71593 0.3 ZSCAN5A MIR596 KBTBD11 GC08P001908 ARHGEF10
GH08F001889 0.6 FANTOM5 11.3 +72.6 72614 0.4 GLIS2 GLIS1 ZBTB17 MIR596 GC08P001908 ARHGEF10
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR596 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR596 Gene

1,817,231 bp from pter
1,817,307 bp from pter
77 bases
Plus strand

Genomic View for MIR596 Gene

Genes around MIR596 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR596 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR596 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR596 Gene

Proteins for MIR596 Gene

Post-translational modifications for MIR596 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR596 Gene

Domains & Families for MIR596 Gene

Gene Families for MIR596 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR596: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR596 Gene

Function for MIR596 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR596 Gene

Localization for MIR596 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR596 Gene

Pathways & Interactions for MIR596 Gene

SuperPathways for MIR596 Gene

No Data Available

Interacting Proteins for MIR596 Gene

Gene Ontology (GO) - Biological Process for MIR596 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR596 Gene

Transcripts for MIR596 Gene

mRNA/cDNA for MIR596 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR596 Gene

No ASD Table

Relevant External Links for MIR596 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR596 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR596 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR596 Gene:

genes like me logo Genes that share expression patterns with MIR596: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR596 Gene

Orthologs for MIR596 Gene

Evolution for MIR596 Gene

Gene Tree for MIR596 (if available)
Gene Tree for MIR596 (if available)

No data available for Orthologs for MIR596 Gene

Paralogs for MIR596 Gene

No data available for Paralogs for MIR596 Gene

Variants for MIR596 Gene

Sequence variations from dbSNP and Humsavar for MIR596 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10713557 -- 1,816,778(+) AGAGC(-/G)GGGGG upstream-variant-2KB
rs11136426 -- 1,815,333(+) TAATT(C/T)ATAAA upstream-variant-2KB
rs111606748 -- 1,817,269(+) GGGAA(C/T)CTGCC nc-transcript-variant
rs111609981 -- 1,816,955(+) CTCCC(C/T)GTTTA upstream-variant-2KB
rs111642093 -- 1,816,343(+) GGGGT(A/G)CAGCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR596 Gene

Variant ID Type Subtype PubMed ID
dgv11822n54 CNV loss 21841781
dgv850n27 CNV loss 19166990
esv3576504 CNV gain 25503493
esv3615841 CNV loss 21293372
esv3615842 CNV gain 21293372
esv3891267 CNV gain 25118596
nsv1017597 CNV loss 25217958
nsv1024325 CNV gain 25217958
nsv1025591 CNV gain 25217958
nsv465277 CNV gain 19166990
nsv470167 CNV gain 18288195
nsv509244 CNV insertion 20534489
nsv609531 CNV gain 21841781
nsv609533 CNV gain 21841781
nsv824454 CNV gain 20364138

Relevant External Links for MIR596 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR596 Gene

Disorders for MIR596 Gene

Relevant External Links for MIR596

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR596 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR596 Gene

Publications for MIR596 Gene

  1. Exploration of Alternative Mechanism for MiR-596-mediated Down-regulation of LGALS3BP in Oral Squamous Cell Carcinoma. (PMID: 26502662) Hui L. (Kokubyo Gakkai Zasshi 2015) 3 64
  2. Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer. (PMID: 23233740) Endo H. … Kozaki K. (Carcinogenesis 2013) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  4. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 64

Products for MIR596 Gene

Sources for MIR596 Gene

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