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Aliases for MIR595 Gene

Subcategory (RNA class) for MIR595 Gene


Quality Score for this RNA gene is


Aliases for MIR595 Gene

  • MicroRNA 595 2 3
  • Hsa-Mir-595 3
  • MIRN595 3

External Ids for MIR595 Gene

Previous HGNC Symbols for MIR595 Gene

  • MIRN595

Previous GeneCards Identifiers for MIR595 Gene

  • GC07M158019
  • GC07M158325

Summaries for MIR595 Gene

Entrez Gene Summary for MIR595 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR595 Gene

MIR595 (MicroRNA 595) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR595 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR595

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR595 Gene

Genomics for MIR595 Gene

Genomic Location for MIR595 Gene

158,532,718 bp from pter
158,532,813 bp from pter
96 bases
Minus strand

Genomic View for MIR595 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR595 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR595 Gene

ORGUL Member Location for MIR595 Gene

ORGUL Member Location for MIR595 gene

No data available for Regulatory Elements for MIR595 Gene

Proteins for MIR595 Gene

Post-translational modifications for MIR595 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR595 Gene

Domains & Families for MIR595 Gene

Gene Families for MIR595 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR595: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR595 Gene

Function for MIR595 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR595 Gene

Localization for MIR595 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR595 Gene

Pathways & Interactions for MIR595 Gene

SuperPathways for MIR595 Gene

No Data Available

Interacting Proteins for MIR595 Gene

Gene Ontology (GO) - Biological Process for MIR595 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR595 Gene

Drugs & Compounds for MIR595 Gene

No Compound Related Data Available

Transcripts for MIR595 Gene

fRNAdb Secondary structures for MIR595 Gene

  • hsa-mir-595_MI0003607_Homo_sapiens_miR-595_stem-loop_hairpin

mRNA/cDNA for MIR595 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR595 Gene

No ASD Table

Relevant External Links for MIR595 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR595 Gene

mRNA expression in normal human tissues for MIR595 Gene

genes like me logo Genes that share expression patterns with MIR595: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR595 Gene

Orthologs for MIR595 Gene

Evolution for MIR595 Gene

Gene Tree for MIR595 (if available)
Gene Tree for MIR595 (if available)

No data available for Orthologs for MIR595 Gene

Paralogs for MIR595 Gene

No data available for Paralogs for MIR595 Gene

Variants for MIR595 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR595 Gene

Variant ID Type Subtype PubMed ID
nsv889636 CNV Gain 21882294
nsv889639 CNV Loss 21882294
dgv7578n71 CNV Gain 21882294
nsv889641 CNV Loss 21882294

Relevant External Links for MIR595 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR595 Gene

Disorders for MIR595 Gene

Relevant External Links for MIR595

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR595: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR595 Gene

Publications for MIR595 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR595 Gene

Sources for MIR595 Gene

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