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Aliases for MIR590 Gene

Subcategory (RNA class) for MIR590 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR590 Gene

  • MicroRNA 590 2 3
  • Hsa-Mir-590 3
  • MIRN590 3

External Ids for MIR590 Gene

ORGUL Members for MIR590 Gene

Previous Symbols for MIR590 Gene

  • MIRN590

Summaries for MIR590 Gene

Entrez Gene Summary for MIR590 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR590 Gene

MIR590 (MicroRNA 590) is a RNA Gene, and belongs to miRNA RNA class. Diseases associated with MIR590 include alzheimer disease.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR590 Gene

Genomics for MIR590 Gene

Genomic Location for MIR590 Gene

Start:
74,191,198 bp from pter
End:
74,191,294 bp from pter
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR590 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR590 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR590 Gene

No data available for Regulatory Elements for MIR590 Gene

Proteins for MIR590 Gene

Post-translational modifications for MIR590 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR590 Gene

Domains for MIR590 Gene

Gene Families for MIR590 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR590: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR590 Gene

Function for MIR590 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR590 Gene

Localization for MIR590 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR590 Gene

Pathways for MIR590 Gene

SuperPathways for MIR590 Gene

No Data Available

Interacting Proteins for MIR590 Gene

Gene Ontology (GO) - Biological Process for MIR590 Gene

None

No data available for Pathways by source for MIR590 Gene

Transcripts for MIR590 Gene

mRNA/cDNA for MIR590 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR590 Gene

No ASD Table

Relevant External Links for MIR590 Gene

GeneLoc Exon Structure for
MIR590
ECgene alternative splicing isoforms for
MIR590

Expression for MIR590 Gene

mRNA expression in normal human tissues for MIR590 Gene

genes like me logo Genes that share expressions with MIR590: view

Orthologs for MIR590 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR590 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-590 37
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-590 37
  • 69 (a)
OneToOne
Species with no ortholog for MIR590:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR590 Gene

ENSEMBL:
Gene Tree for MIR590 (if available)
TreeFam:
Gene Tree for MIR590 (if available)

Paralogs for MIR590 Gene

No data available for Paralogs for MIR590 Gene

Variants for MIR590 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR590 Gene

Variant ID Type Subtype PubMed ID
nsv464563 CNV Gain 19166990
nsv831030 CNV Gain 17160897

Relevant External Links for MIR590 Gene

HapMap Linkage Disequilibrium report
MIR590

No data available for Sequence variations from dbSNP and Humsavar for MIR590 Gene

Disorders for MIR590 Gene

(1) MalaCards Diseases for MIR590 Gene

Search for MIR590 Gene in MalaCards »
genes like me logo Genes that share disorders with MIR590: view

No data available for UniProtKB/Swiss-Prot for MIR590 Gene

Publications for MIR590 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Role of hnRNP-A1 and miR-590-3p in neuronal death: genetics and expression analysis in patients with Alzheimer disease and frontotemporal lobar degeneration. (PMID: 21548758) Villa C. … Galimberti D. (Rejuvenation Res 2011) 3
  5. MicroRNA-590-5p regulates proliferation and invasion in human hepatocellular carcinoma cells by targeting TGF-I^ RII. (PMID: 22684895) Jiang X. … Chen D. (Mol. Cells 2012) 3

Products for MIR590 Gene

Sources for MIR590 Gene

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