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Aliases for MIR588 Gene

Subcategory (RNA class) for MIR588 Gene


Quality Score for this RNA gene is


Aliases for MIR588 Gene

  • MicroRNA 588 2 3
  • Hsa-Mir-588 3
  • MIRN588 3

External Ids for MIR588 Gene

ORGUL Members for MIR588 Gene

Previous HGNC Symbols for MIR588 Gene

  • MIRN588

Previous GeneCards Identifiers for MIR588 Gene

  • GC06P126848

Summaries for MIR588 Gene

Entrez Gene Summary for MIR588 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR588 Gene

MIR588 (MicroRNA 588) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR588 include ulcerative colitis.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR588 Gene

Genomics for MIR588 Gene

Genomic Location for MIR588 Gene

126,484,631 bp from pter
126,484,713 bp from pter
83 bases
Plus strand

Genomic View for MIR588 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR588 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR588 Gene

No data available for Regulatory Elements for MIR588 Gene

Proteins for MIR588 Gene

Post-translational modifications for MIR588 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR588 Gene

Domains for MIR588 Gene

Gene Families for MIR588 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR588: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR588 Gene

Function for MIR588 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR588 Gene

Localization for MIR588 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR588 Gene

Pathways for MIR588 Gene

SuperPathways for MIR588 Gene

No Data Available

Interacting Proteins for MIR588 Gene

Gene Ontology (GO) - Biological Process for MIR588 Gene


No data available for Pathways by source for MIR588 Gene

Transcripts for MIR588 Gene

mRNA/cDNA for MIR588 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR588 Gene

No ASD Table

Relevant External Links for MIR588 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR588 Gene

mRNA expression in normal human tissues for MIR588 Gene

genes like me logo Genes that share expressions with MIR588: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR588 Gene

Orthologs for MIR588 Gene

Evolution for MIR588 Gene

Gene Tree for MIR588 (if available)
Gene Tree for MIR588 (if available)

No data available for Orthologs for MIR588 Gene

Paralogs for MIR588 Gene

No data available for Paralogs for MIR588 Gene

Variants for MIR588 Gene

Sequence variations from dbSNP and Humsavar for MIR588 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs990692 -- 126,483,909(+) catgt(G/T)tgaaa upstream-variant-2KB
rs2050644 -- 126,484,109(+) CTTCT(A/G)AATTC upstream-variant-2KB
rs61069279 -- 126,484,857(+) GGTGA(A/G)CATCA downstream-variant-500B
rs116912257 -- 126,484,445(+) CTGTG(A/G)TGAAG upstream-variant-2KB
rs141055898 -- 126,485,153(+) CTCTA(A/G)GGCCT downstream-variant-500B

Relevant External Links for MIR588 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR588 Gene

Disorders for MIR588 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR588 Gene in MalaCards »

(1) Disease for MIR588 Gene

genes like me logo Genes that share disorders with MIR588: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR588 Gene

Publications for MIR588 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. Genetic predictors of medically refractory ulcerative colitis. (PMID: 20848476) Haritunians T. … McGovern D.P. (Inflamm. Bowel Dis. 2010) 3

Products for MIR588 Gene

Sources for MIR588 Gene

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