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Aliases for MIR583 Gene

Subcategory (RNA class) for MIR583 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR583 Gene

  • MicroRNA 583 2 3
  • Hsa-Mir-583 3
  • MIRN583 3

External Ids for MIR583 Gene

ORGUL Members for MIR583 Gene

Previous HGNC Symbols for MIR583 Gene

  • MIRN583

Previous GeneCards Identifiers for MIR583 Gene

  • GC05P095441

Summaries for MIR583 Gene

Entrez Gene Summary for MIR583 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR583 Gene

MIR583 (MicroRNA 583) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR583 Gene

Genomics for MIR583 Gene

Genomic Location for MIR583 Gene

Start:
96,079,138 bp from pter
End:
96,079,212 bp from pter
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR583 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR583 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR583 Gene

No data available for Regulatory Elements for MIR583 Gene

Proteins for MIR583 Gene

Post-translational modifications for MIR583 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR583 Gene

Domains for MIR583 Gene

Gene Families for MIR583 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR583: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR583 Gene

Function for MIR583 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR583 Gene

Localization for MIR583 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR583 Gene

Pathways for MIR583 Gene

SuperPathways for MIR583 Gene

No Data Available

Interacting Proteins for MIR583 Gene

Gene Ontology (GO) - Biological Process for MIR583 Gene

None

No data available for Pathways by source for MIR583 Gene

Transcripts for MIR583 Gene

mRNA/cDNA for MIR583 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR583 Gene

No ASD Table

Relevant External Links for MIR583 Gene

GeneLoc Exon Structure for
MIR583
ECgene alternative splicing isoforms for
MIR583

Expression for MIR583 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR583 Gene

Orthologs for MIR583 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR583 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-583 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR583:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR583 Gene

ENSEMBL:
Gene Tree for MIR583 (if available)
TreeFam:
Gene Tree for MIR583 (if available)

Paralogs for MIR583 Gene

No data available for Paralogs for MIR583 Gene

Variants for MIR583 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR583 Gene

Variant ID Type Subtype PubMed ID
dgv1819e1 CNV Complex 17122850
nsv823146 CNV Gain 20364138
esv34203 CNV Gain 17911159
dgv348n21 CNV Loss 19592680
nsv4923 CNV Insertion 18451855

Relevant External Links for MIR583 Gene

HapMap Linkage Disequilibrium report
MIR583

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR583 Gene

Disorders for MIR583 Gene

No disorders were found for MIR583 Gene.

No data available for UniProtKB/Swiss-Prot for MIR583 Gene

Publications for MIR583 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for MIR583 Gene

Sources for MIR583 Gene

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