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Aliases for MIR579 Gene

Subcategory (RNA class) for MIR579 Gene


Quality Score for this RNA gene is


Aliases for MIR579 Gene

  • MicroRNA 579 2 3 5
  • Hsa-Mir-579 3
  • MIRN579 3

External Ids for MIR579 Gene

Previous HGNC Symbols for MIR579 Gene

  • MIRN579

Summaries for MIR579 Gene

Entrez Gene Summary for MIR579 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR579 Gene

MIR579 (MicroRNA 579) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR579 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR579

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR579 Gene

Genomics for MIR579 Gene

Regulatory Elements for MIR579 Gene

Enhancers for MIR579 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F032442 1.4 FANTOM5 ENCODE 10.4 -50.5 -50461 5.0 HDGF PKNOX1 ARNT MLX CREB3L1 ARID4B SIN3A DMAP1 YY1 SLC30A9 GOLPH3 ENSG00000249572 MIR579 RPS8P8 MTMR12 ZFR LOC646616
GH05F032230 1.3 Ensembl ENCODE 11.2 +161.6 161562 5.3 MLX ZFP64 ARID4B DMAP1 ZNF2 ZNF48 YY1 SLC30A9 ZNF121 ZNF143 GOLPH3 MIR579 ZFR MTMR12 GC05M032236 RNU6-1079P GC05P032221
GH05F032329 1.2 Ensembl ENCODE 11.2 +63.6 63572 3.2 ATF1 ARID4B DMAP1 ZNF143 DEK SP5 REST PPARG KAT8 MIER3 MTMR12 MIR579 ZFR GOLPH3 LOC646616 SUB1 GC05P032360
GH05F032489 1.2 Ensembl ENCODE 11.2 -95.7 -95748 1.7 SIN3A ARID4B FEZF1 ZNF48 ZNF2 ZNF121 ZNF143 DEK TSHZ1 REST LOC646616 SUB1 ZFR MIR579
GH05F032209 1.2 Ensembl ENCODE 11 +183.6 183581 1.8 ELF3 HDGF TBL1XR1 ARID4B RAD21 RARA YY1 KAT2B ETV6 CREM GOLPH3 MIR579 ZFR MTMR12 RPL27P10 GC05P032207 PIR52245
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR579 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR579 Gene

32,394,378 bp from pter
32,394,475 bp from pter
98 bases
Minus strand

Genomic View for MIR579 Gene

Genes around MIR579 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR579 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR579 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR579 Gene

ORGUL Member Location for MIR579 Gene

ORGUL Member Location for MIR579 gene

Proteins for MIR579 Gene

Post-translational modifications for MIR579 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR579 Gene

Domains & Families for MIR579 Gene

Gene Families for MIR579 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR579: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR579 Gene

Function for MIR579 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR579 Gene

Localization for MIR579 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR579 Gene

Pathways & Interactions for MIR579 Gene

SuperPathways for MIR579 Gene

No Data Available

Interacting Proteins for MIR579 Gene

Gene Ontology (GO) - Biological Process for MIR579 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR579 Gene

Transcripts for MIR579 Gene

fRNAdb Secondary structures for MIR579 Gene

  • hsa-mir-579_MI0003586_Homo_sapiens_miR-579_stem-loop_hairpin

mRNA/cDNA for MIR579 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR579 Gene

No ASD Table

Relevant External Links for MIR579 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR579 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR579 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR579 Gene:

genes like me logo Genes that share expression patterns with MIR579: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR579 Gene

Orthologs for MIR579 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR579 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-579 35
  • 100 (a)
Species where no ortholog for MIR579 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR579 Gene

Gene Tree for MIR579 (if available)
Gene Tree for MIR579 (if available)

Paralogs for MIR579 Gene

No data available for Paralogs for MIR579 Gene

Variants for MIR579 Gene

Sequence variations from dbSNP and Humsavar for MIR579 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs113421901 -- 32,394,051(+) AATCC(A/G)AATTT intron-variant, downstream-variant-500B
rs139572588 -- 32,395,813(+) TCTAG(-/CTTA)CTTTA intron-variant, upstream-variant-2KB
rs139768019 -- 32,394,717(+) AACAT(C/T)TGTAT intron-variant, upstream-variant-2KB
rs140544134 -- 32,394,005(+) TTTTA(C/T)ATATG intron-variant, downstream-variant-500B
rs142128604 -- 32,396,348(+) TTTAC(A/G)TATTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR579 Gene

Variant ID Type Subtype PubMed ID
nsv1021781 CNV gain 25217958
esv2759338 CNV loss 17122850
esv2730031 CNV deletion 23290073

Relevant External Links for MIR579 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR579 Gene

Disorders for MIR579 Gene

Relevant External Links for MIR579

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR579 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR579 Gene

Publications for MIR579 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 3 64
  2. Alternative polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR. (PMID: 25799583) Hinske L.C. … Kreth S. (PLoS ONE 2015) 3 64
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  4. MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-I+ during TLR4-induced gene reprogramming. (PMID: 21562054) El Gazzar M. … McCall C.E. (J. Leukoc. Biol. 2011) 3 64
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 64

Products for MIR579 Gene

Sources for MIR579 Gene

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