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Aliases for MIR578 Gene

Subcategory (RNA class) for MIR578 Gene


Quality Score for this RNA gene is


Aliases for MIR578 Gene

  • MicroRNA 578 2 3 5
  • Hsa-Mir-578 3
  • MIRN578 3

External Ids for MIR578 Gene

ORGUL Members for MIR578 Gene

Previous HGNC Symbols for MIR578 Gene

  • MIRN578

Previous GeneCards Identifiers for MIR578 Gene

  • GC04P166527
  • GC04P166307

Summaries for MIR578 Gene

Entrez Gene Summary for MIR578 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR578 Gene

MIR578 (MicroRNA 578) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR578 Gene

Genomics for MIR578 Gene

Regulatory Elements for MIR578 Gene

Enhancers for MIR578 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F165460 1 Ensembl ENCODE 10.9 +75.1 75130 1.7 CTCF TAL1 ARID1B NCOR1 GATA2 ADNP IKZF1 E2F6 MGA MIR578 CPE GC04P165491 GC04M165414
GH04F165439 1.3 FANTOM5 Ensembl ENCODE 10.7 +54.1 54141 1.6 PKNOX1 INSM2 ZNF76 KLF17 FEZF1 ZNF2 ZEB1 RFX5 ZNF366 SCRT2 MIR578 HADHAP1 CPE FAM218A GC04M165414 GC04P165491
GH04F165131 1 Ensembl 10.3 -254.7 -254742 0.6 CTCF PKNOX1 ZNF654 SAP130 ARID4B TRIM22 REST RAD21 JUND PBX2 KLHL2 TMEM192 MIR578 TRIM75P
GH04F165394 0.4 FANTOM5 0.4 +8.4 8427 0.2 GTF3C2 MIR578 HADHAP1
GH04F165398 0.3 FANTOM5 0.4 +12.0 11999 0.4 RFX1 CPE HADHAP1 MIR578
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR578 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR578 Gene

165,386,242 bp from pter
165,386,337 bp from pter
96 bases
Plus strand

Genomic View for MIR578 Gene

Genes around MIR578 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR578 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR578 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR578 Gene

Proteins for MIR578 Gene

Post-translational modifications for MIR578 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR578 Gene

Domains & Families for MIR578 Gene

Gene Families for MIR578 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR578: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR578 Gene

Function for MIR578 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR578 Gene

Localization for MIR578 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR578 Gene

Pathways & Interactions for MIR578 Gene

SuperPathways for MIR578 Gene

No Data Available

Interacting Proteins for MIR578 Gene

Gene Ontology (GO) - Biological Process for MIR578 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR578 Gene

Transcripts for MIR578 Gene

mRNA/cDNA for MIR578 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR578 Gene

No ASD Table

Relevant External Links for MIR578 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR578 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR578 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR578 Gene:

genes like me logo Genes that share expression patterns with MIR578: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR578 Gene

Orthologs for MIR578 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR578 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia cfa-mir-578 35
  • 32 (a)
Species where no ortholog for MIR578 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR578 Gene

Gene Tree for MIR578 (if available)
Gene Tree for MIR578 (if available)

Paralogs for MIR578 Gene

No data available for Paralogs for MIR578 Gene

Variants for MIR578 Gene

Sequence variations from dbSNP and Humsavar for MIR578 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs11100610 -- 165,386,110(+) CTCTA(C/T)CTCCC intron-variant, upstream-variant-2KB
rs111624459 -- 165,384,247(+) GGTTT(C/G)TATAT intron-variant, upstream-variant-2KB
rs112658493 -- 165,384,515(+) ACTTG(C/G)GGGGC intron-variant, upstream-variant-2KB
rs114396219 -- 165,385,609(+) GCCTG(C/T)TTGCC intron-variant, upstream-variant-2KB
rs12509669 -- 165,386,150(+) GTGAT(A/G)ATTAA intron-variant, upstream-variant-2KB

Relevant External Links for MIR578 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR578 Gene

Disorders for MIR578 Gene

Relevant External Links for MIR578

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR578 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR578 Gene

Publications for MIR578 Gene

  1. MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis. (PMID: 25333258) Danza K. … Tommasi S. (Oncotarget 2015) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  3. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 64

Products for MIR578 Gene

Sources for MIR578 Gene

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