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Aliases for MIR574 Gene

Subcategory (RNA class) for MIR574 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR574 Gene

  • MicroRNA 574 2 3
  • MIR574-3p 3 6
  • Hsa-Mir-574 3
  • MIRN574 3

External Ids for MIR574 Gene

ORGUL Members for MIR574 Gene

Previous HGNC Symbols for MIR574 Gene

  • MIRN574

Previous GeneCards Identifiers for MIR574 Gene

  • GC04U900958
  • GC04P038554
  • GC04P038869

Summaries for MIR574 Gene

Entrez Gene Summary for MIR574 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR574 Gene

MIR574 (MicroRNA 574) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR574 include fragile x-associated tremor/ataxia syndrome.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR574 Gene

Genomics for MIR574 Gene

Genomic Location for MIR574 Gene

Start:
38,868,032 bp from pter
End:
38,868,127 bp from pter
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR574 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR574 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR574 Gene

No data available for Regulatory Elements for MIR574 Gene

Proteins for MIR574 Gene

Post-translational modifications for MIR574 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR574 Gene

Domains for MIR574 Gene

Gene Families for MIR574 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR574: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR574 Gene

Function for MIR574 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR574 Gene

Localization for MIR574 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR574 Gene

Pathways for MIR574 Gene

SuperPathways for MIR574 Gene

No Data Available

Interacting Proteins for MIR574 Gene

Gene Ontology (GO) - Biological Process for MIR574 Gene

None

No data available for Pathways by source for MIR574 Gene

Transcripts for MIR574 Gene

mRNA/cDNA for MIR574 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR574 Gene

No ASD Table

Relevant External Links for MIR574 Gene

GeneLoc Exon Structure for
MIR574
ECgene alternative splicing isoforms for
MIR574

Expression for MIR574 Gene

mRNA expression in normal human tissues for MIR574 Gene

genes like me logo Genes that share expressions with MIR574: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR574 Gene

Orthologs for MIR574 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR574 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 56 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 65 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-574 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir574 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 58 (a)
OneToMany
-- 36
  • 69 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 54 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 54 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii CU459159.1 36
  • 51 (a)
ManyToMany
Species with no ortholog for MIR574:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR574 Gene

ENSEMBL:
Gene Tree for MIR574 (if available)
TreeFam:
Gene Tree for MIR574 (if available)

Paralogs for MIR574 Gene

No data available for Paralogs for MIR574 Gene

Variants for MIR574 Gene

Relevant External Links for MIR574 Gene

HapMap Linkage Disequilibrium report
MIR574

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR574 Gene

Disorders for MIR574 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR574 Gene including...

Search for MIR574 Gene in MalaCards »
genes like me logo Genes that share disorders with MIR574: view

No data available for UniProtKB/Swiss-Prot for MIR574 Gene

Publications for MIR574 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3
  5. miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer. (PMID: 21258252) Foss K.M. … Weiss G.J. (J Thorac Oncol 2011) 3

Products for MIR574 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR574
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR574
    • Block miRNA regulation of MIR574 using miScript Target Protectors

    Sources for MIR574 Gene

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