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Aliases for MIR5708 Gene

Subcategory (RNA class) for MIR5708 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5708 Gene

  • MicroRNA 5708 2 3 5
  • Hsa-Mir-5708 3

External Ids for MIR5708 Gene

Previous GeneCards Identifiers for MIR5708 Gene

  • GC08U901600
  • GC08P081154

Summaries for MIR5708 Gene

Entrez Gene Summary for MIR5708 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5708 Gene

MIR5708 (MicroRNA 5708) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5708 Gene

Genomics for MIR5708 Gene

Regulatory Elements for MIR5708 Gene

Enhancers for MIR5708 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F080240 1.2 Ensembl ENCODE 0.8 -0.7 -689 1.0 ELF3 ZNF76 ARID4B SIN3A ZNF48 ZNF2 RAD21 RARA ZNF143 MIXL1 ENSG00000206649 ENSG00000251867 ZBTB10 RNU6-1213P RNU2-71P MIR5708 LOC105375920
GH08F080249 0.8 ENCODE 0.4 +8.4 8382 0.2 SOX13 CTCF PKNOX1 SIN3A RAD21 TEAD3 GTF3C2 GATA3 CTBP1 GATA2 RNU6-1213P MIR5708 ENSG00000253238
GH08F080256 1 Ensembl ENCODE 0.3 +16.3 16331 3.3 ZNF146 JUN MAX EBF1 ZNF121 ZNF316 ZNF366 FOSL2 FOS ZHX2 TPD52 ENSG00000206649 RNU6-1213P ENSG00000253238 MIR5708
GH08F080253 0.6 ENCODE 0.4 +12.2 12232 0.2 CTCF MAFG RAD21 FOS NFE2 PRDM10 EMSY MAFK ENSG00000206649 TPD52 RNU6-1213P ENSG00000253238 MIR5708
GH08F080246 0.5 ENCODE 0.4 +6.0 6004 2.0 OSR2 GLIS1 HLF ZIC2 RNU6-1213P TPD52 MIR5708 ENSG00000253238
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5708 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5708 Gene

Chromosome:
8
Start:
80,241,389 bp from pter
End:
80,241,473 bp from pter
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR5708 Gene

Genes around MIR5708 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5708 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5708 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5708 Gene

Proteins for MIR5708 Gene

Post-translational modifications for MIR5708 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5708 Gene

Domains & Families for MIR5708 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5708 Gene

Function for MIR5708 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5708 Gene

Localization for MIR5708 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5708 Gene

Pathways & Interactions for MIR5708 Gene

SuperPathways for MIR5708 Gene

No Data Available

Interacting Proteins for MIR5708 Gene

Gene Ontology (GO) - Biological Process for MIR5708 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5708 Gene

Transcripts for MIR5708 Gene

mRNA/cDNA for MIR5708 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5708 Gene

No ASD Table

Relevant External Links for MIR5708 Gene

GeneLoc Exon Structure for
MIR5708
ECgene alternative splicing isoforms for
MIR5708

Expression for MIR5708 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5708 Gene:

MIR5708
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5708 Gene

Orthologs for MIR5708 Gene

Evolution for MIR5708 Gene

ENSEMBL:
Gene Tree for MIR5708 (if available)
TreeFam:
Gene Tree for MIR5708 (if available)

No data available for Orthologs for MIR5708 Gene

Paralogs for MIR5708 Gene

No data available for Paralogs for MIR5708 Gene

Variants for MIR5708 Gene

Sequence variations from dbSNP and Humsavar for MIR5708 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10086782 -- 80,241,536(+) AGCCT(A/G)GCCAA downstream-variant-500B
rs10107554 -- 80,239,746(+) cctca(C/G)tctgt upstream-variant-2KB
rs112043995 -- 80,241,965(+) CATTC(-/T)TTTTT downstream-variant-500B
rs112713490 -- 80,240,862(+) CTCTG(C/T)TCTGG upstream-variant-2KB
rs112943578 -- 80,241,713(+) TCTCA(-/AAAC)AAACA downstream-variant-500B

Relevant External Links for MIR5708 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5708

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5708 Gene

Disorders for MIR5708 Gene

Relevant External Links for MIR5708

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5708

No disorders were found for MIR5708 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5708 Gene

Publications for MIR5708 Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A. … Wang Y. (PLoS ONE 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5708 Gene

Sources for MIR5708 Gene

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