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Aliases for MIR5708 Gene

Subcategory (RNA class) for MIR5708 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5708 Gene

  • MicroRNA 5708 2 3
  • Hsa-Mir-5708 3

External Ids for MIR5708 Gene

Previous GeneCards Identifiers for MIR5708 Gene

  • GC08U901600
  • GC08P081154

Summaries for MIR5708 Gene

Entrez Gene Summary for MIR5708 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5708 Gene

MIR5708 (MicroRNA 5708) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5708 Gene

Genomics for MIR5708 Gene

Genomic Location for MIR5708 Gene

Start:
80,241,389 bp from pter
End:
80,241,473 bp from pter
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR5708 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR5708 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5708 Gene

No data available for Regulatory Elements for MIR5708 Gene

Proteins for MIR5708 Gene

Post-translational modifications for MIR5708 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5708 Gene

Domains for MIR5708 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5708 Gene

Function for MIR5708 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR5708 Gene

Localization for MIR5708 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5708 Gene

Pathways for MIR5708 Gene

SuperPathways for MIR5708 Gene

No Data Available

Interacting Proteins for MIR5708 Gene

Gene Ontology (GO) - Biological Process for MIR5708 Gene

None

No data available for Pathways by source for MIR5708 Gene

Transcripts for MIR5708 Gene

mRNA/cDNA for MIR5708 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5708 Gene

No ASD Table

Relevant External Links for MIR5708 Gene

GeneLoc Exon Structure for
MIR5708
ECgene alternative splicing isoforms for
MIR5708

Expression for MIR5708 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR5708 Gene

Orthologs for MIR5708 Gene

Evolution for MIR5708 Gene

ENSEMBL:
Gene Tree for MIR5708 (if available)
TreeFam:
Gene Tree for MIR5708 (if available)

No data available for Orthologs for MIR5708 Gene

Paralogs for MIR5708 Gene

No data available for Paralogs for MIR5708 Gene

Variants for MIR5708 Gene

Sequence variations from dbSNP and Humsavar for MIR5708 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs10086782 -- 80,241,536(+) AGCCT(A/G)GCCAA downstream-variant-500B
rs10107554 -- 80,239,746(+) cctca(C/G)tctgt upstream-variant-2KB
rs12334757 -- 80,240,996(+) CACGG(C/T)TGCAG upstream-variant-2KB
rs12334822 -- 80,241,466(+) tcatg(C/T)ctgta nc-transcript-variant
rs12335120 -- 80,241,344(+) aattc(C/T)ctgcc upstream-variant-2KB

Relevant External Links for MIR5708 Gene

HapMap Linkage Disequilibrium report
MIR5708

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR5708 Gene

Disorders for MIR5708 Gene

No disorders were found for MIR5708 Gene.

No data available for UniProtKB/Swiss-Prot for MIR5708 Gene

Publications for MIR5708 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A. … Wang Y. (PLoS ONE 2011) 3

Products for MIR5708 Gene

Sources for MIR5708 Gene

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