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Aliases for MIR5703 Gene

Subcategory (RNA class) for MIR5703 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5703 Gene

  • MicroRNA 5703 2 3 5
  • Hsa-Mir-5703 3
  • Mir-5703 3

External Ids for MIR5703 Gene

Previous GeneCards Identifiers for MIR5703 Gene

  • GC02U902469
  • GC02P228339

Summaries for MIR5703 Gene

Entrez Gene Summary for MIR5703 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5703 Gene

MIR5703 (MicroRNA 5703) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5703 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5703 Gene

Genomics for MIR5703 Gene

Regulatory Elements for MIR5703 Gene

Enhancers for MIR5703 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H227461 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -6.7 -6719 7 PKNOX1 ATF1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF121 GLIS2 ZNF207 TM4SF20 AGFG1 MIR5703 ENSG00000284629
GH02H227449 1.6 Ensembl ENCODE dbSUPER 0.3 -21.0 -20993 3 PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B DMAP1 YY1 SLC30A9 ZNF766 AGFG1 MIR5703 ENSG00000284629
GH02H227459 1.1 Ensembl ENCODE 0.4 -11.9 -11907 0 PKNOX1 RB1 ATF7 RUNX3 IKZF2 CREM ZNF362 CBFB JUNB ZNF843 MIR5703 ENSG00000284629
GH02H227453 0.9 dbSUPER 0.4 -17.6 -17649 1 FOXA2 MLX ARID4B DMAP1 RAD21 THRB ZSCAN9 RARA SCRT2 CREM TM4SF20 MIR5703 ENSG00000284629
GH02H227414 1.4 FANTOM5 Ensembl ENCODE 0.2 -56.2 -56207 3 SOX13 JUN BACH1 MAX ZIC2 ZNF644 RARA TEAD3 ZNF316 LCORL AGFG1 TM4SF20 CCL20 ENSG00000284629 MIR5703
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5703 on UCSC Golden Path with GeneCards custom track

Promoters for MIR5703 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000131447 768 1801 ARID4B SIN3A DMAP1 YY1 ETS1 GLIS2 ZNF143 ZNF207 RUNX3 ZHX2

Genomic Location for MIR5703 Gene

Chromosome:
2
Start:
227,472,132 bp from pter
End:
227,472,187 bp from pter
Size:
56 bases
Orientation:
Plus strand

Genomic View for MIR5703 Gene

Genes around MIR5703 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5703 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5703 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5703 Gene

Proteins for MIR5703 Gene

Post-translational modifications for MIR5703 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5703 Gene

Domains & Families for MIR5703 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5703 Gene

Function for MIR5703 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5703
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5703 Gene

Localization for MIR5703 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5703 Gene

Pathways & Interactions for MIR5703 Gene

SuperPathways for MIR5703 Gene

No Data Available

Interacting Proteins for MIR5703 Gene

Gene Ontology (GO) - Biological Process for MIR5703 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5703 Gene

Drugs & Compounds for MIR5703 Gene

No Compound Related Data Available

Transcripts for MIR5703 Gene

mRNA/cDNA for MIR5703 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5703
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5703 Gene

No ASD Table

Relevant External Links for MIR5703 Gene

GeneLoc Exon Structure for
MIR5703
ECgene alternative splicing isoforms for
MIR5703

Expression for MIR5703 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5703 Gene:

MIR5703
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5703 Gene

Orthologs for MIR5703 Gene

Evolution for MIR5703 Gene

ENSEMBL:
Gene Tree for MIR5703 (if available)
TreeFam:
Gene Tree for MIR5703 (if available)

No data available for Orthologs for MIR5703 Gene

Paralogs for MIR5703 Gene

No data available for Paralogs for MIR5703 Gene

Variants for MIR5703 Gene

Sequence variations from dbSNP and Humsavar for MIR5703 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000289204 -- 227,471,491(+) TTAGA(A/G)GATGT upstream-variant-2KB
rs1000392210 -- 227,471,867(+) CGGCA(A/C)GGTGA upstream-variant-2KB
rs1000982797 -- 227,470,385(+) TCATA(C/T)TTTTA upstream-variant-2KB
rs1001266540 -- 227,470,572(+) GTTTT(C/T)ATTTT upstream-variant-2KB
rs1001324440 -- 227,470,660(+) GGGGA(G/T)GGAGG upstream-variant-2KB

Relevant External Links for MIR5703 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5703

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5703 Gene

Disorders for MIR5703 Gene

Relevant External Links for MIR5703

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5703

No disorders were found for MIR5703 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5703 Gene

Publications for MIR5703 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR5703 Gene

Sources for MIR5703 Gene

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