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Aliases for MIR5691 Gene

Subcategory (RNA class) for MIR5691 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5691 Gene

  • MicroRNA 5691 2 3 5
  • Hsa-Mir-5691 3

External Ids for MIR5691 Gene

Previous GeneCards Identifiers for MIR5691 Gene

  • GC11U901905

Summaries for MIR5691 Gene

Entrez Gene Summary for MIR5691 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5691 Gene

MIR5691 (MicroRNA 5691) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5691 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5691 Gene

Genomics for MIR5691 Gene

GeneHancer (GH) Regulatory Elements for MIR5691 Gene

Promoters and enhancers for MIR5691 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I009091 Promoter 1.2 EPDnew Ensembl 550.8 -1.1 -1122 1 RING1 SUZ12 EZH2 MIR5691 SCUBE2 KRT8P41 TMEM41B
GH11I009088 Enhancer 0.4 ENCODE 550.8 +1.0 953 1 NCOA3 KLF1 MIR5691 TMEM9B-AS1 TMEM9B SCUBE2 LOC105376541
GH11I009060 Enhancer 1 Ensembl ENCODE 0.3 +29.4 29443 0.7 PKNOX1 BMI1 BATF KLF5 IRF4 RAD21 ZNF143 ATF7 ETV6 BCLAF1 MIR5691 LOC105376541 SCUBE2
GH11I009093 Enhancer 0.3 ENCODE 0.8 -3.2 -3170 0.2 CTCF KRT8P41 MIR5691 SCUBE2
GH11I009075 Enhancer 0.5 ENCODE 0.4 +13.5 13510 1.8 ZNF217 CTBP1 JUND GATA3 NFIB CUX1 TCF7L2 SCUBE2 AKIP1 MIR5691 LOC105376541
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5691 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5691 Gene

Genomic Locations for MIR5691 Gene
chr11:9,090,312-9,090,379
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand
chr11:9,111,859-9,111,926
(GRCh37/hg19)

Genomic View for MIR5691 Gene

Genes around MIR5691 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5691 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5691 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5691 Gene

Proteins for MIR5691 Gene

Post-translational modifications for MIR5691 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5691 Gene

Domains & Families for MIR5691 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5691 Gene

Function for MIR5691 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5691 Gene

Localization for MIR5691 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5691 Gene

Pathways & Interactions for MIR5691 Gene

SuperPathways for MIR5691 Gene

No Data Available

Interacting Proteins for MIR5691 Gene

Gene Ontology (GO) - Biological Process for MIR5691 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5691 Gene

Drugs & Compounds for MIR5691 Gene

No Compound Related Data Available

Transcripts for MIR5691 Gene

mRNA/cDNA for MIR5691 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5691 Gene

No ASD Table

Relevant External Links for MIR5691 Gene

GeneLoc Exon Structure for
MIR5691
ECgene alternative splicing isoforms for
MIR5691

Expression for MIR5691 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5691 Gene:

MIR5691
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5691 Gene

Orthologs for MIR5691 Gene

Evolution for MIR5691 Gene

ENSEMBL:
Gene Tree for MIR5691 (if available)
TreeFam:
Gene Tree for MIR5691 (if available)

No data available for Orthologs for MIR5691 Gene

Paralogs for MIR5691 Gene

No data available for Paralogs for MIR5691 Gene

Variants for MIR5691 Gene

Sequence variations from dbSNP and Humsavar for MIR5691 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1002918769 -- 9,091,052(-) T/A upstream_transcript_variant
rs1003380297 -- 9,091,233(-) G/A upstream_transcript_variant
rs1003672468 -- 9,092,355(-) A/G upstream_transcript_variant
rs1004009637 -- 9,090,127(-) C/T downstream_transcript_variant
rs1005323142 -- 9,091,946(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5691 Gene

Variant ID Type Subtype PubMed ID
esv33264 CNV loss 17666407
nsv467706 CNV loss 19166990
nsv499766 OTHER inversion 21111241
nsv553454 CNV loss 21841781
nsv553455 CNV loss 21841781
nsv7215 OTHER inversion 18451855
nsv951307 CNV deletion 24416366

Additional Variant Information for MIR5691 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5691

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5691 Gene

Disorders for MIR5691 Gene

Additional Disease Information for MIR5691

No disorders were found for MIR5691 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5691 Gene

Publications for MIR5691 Gene

  1. Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain. (PMID: 23279374) Athanasiadis G … Soria JM (Journal of thrombosis and haemostasis : JTH 2013) 3 58
  2. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5691 Gene

Sources for MIR5691 Gene

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