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Aliases for MIR5689 Gene

Subcategory (RNA class) for MIR5689 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5689 Gene

  • MicroRNA 5689 2 3 5
  • Hsa-Mir-5689 3

External Ids for MIR5689 Gene

Previous GeneCards Identifiers for MIR5689 Gene

  • GC06U902248
  • GC06P010441
  • GC06P010442
  • GC06P010443

Summaries for MIR5689 Gene

Entrez Gene Summary for MIR5689 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5689 Gene

MIR5689 (MicroRNA 5689) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5689 Gene

Genomics for MIR5689 Gene

Regulatory Elements for MIR5689 Gene

Enhancers for MIR5689 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G010440 1.4 FANTOM5 Ensembl ENCODE 0.7 +2.0 2039 1.9 TBP CTCF PKNOX1 MXI1 TAF1 JUN MAX SIN3A CEBPG RAD21 TFAP2A TMEM14C TMEM14B PAK1IP1 GCNT2 MIR5689 MRPL48P1
GH06G010449 1.1 Ensembl ENCODE 0.4 +12.1 12110 4.2 TBP ATF1 SIN3A RAD21 RFX5 RCOR1 FOS CREM EGR2 SMARCC1 ENSG00000228478 TFAP2A TFAP2A-AS1 GCNT2 MRPL48P1 MIR5689
GH06G010458 0.6 FANTOM5 0.4 +18.4 18408 0.1 ZNF335 ZNF316 SMARCA4 MRPL48P1 MIR5689
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5689 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5689 Gene

Chromosome:
6
Start:
10,439,717 bp from pter
End:
10,439,794 bp from pter
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR5689 Gene

Genes around MIR5689 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5689 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5689 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5689 Gene

Proteins for MIR5689 Gene

Post-translational modifications for MIR5689 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5689 Gene

Domains & Families for MIR5689 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5689 Gene

Function for MIR5689 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5689 Gene

Localization for MIR5689 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5689 Gene

Pathways & Interactions for MIR5689 Gene

SuperPathways for MIR5689 Gene

No Data Available

Interacting Proteins for MIR5689 Gene

Gene Ontology (GO) - Biological Process for MIR5689 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5689 Gene

Transcripts for MIR5689 Gene

mRNA/cDNA for MIR5689 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5689 Gene

No ASD Table

Relevant External Links for MIR5689 Gene

GeneLoc Exon Structure for
MIR5689
ECgene alternative splicing isoforms for
MIR5689

Expression for MIR5689 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5689 Gene:

MIR5689
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5689 Gene

Orthologs for MIR5689 Gene

Evolution for MIR5689 Gene

ENSEMBL:
Gene Tree for MIR5689 (if available)
TreeFam:
Gene Tree for MIR5689 (if available)

No data available for Orthologs for MIR5689 Gene

Paralogs for MIR5689 Gene

No data available for Paralogs for MIR5689 Gene

Variants for MIR5689 Gene

Sequence variations from dbSNP and Humsavar for MIR5689 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1001447318 -- 10,439,269(+) ATTTT(C/T)GTATT intron-variant, upstream-variant-2KB
rs1002383809 -- 10,439,959(+) CTTAA(C/G)TTTTC intron-variant, downstream-variant-500B
rs1002894220 -- 10,437,979(+) GCTTA(C/T)AAGGG intron-variant, upstream-variant-2KB
rs1004979134 -- 10,438,545(+) TCAAC(-/AAAG)AAAGA intron-variant, upstream-variant-2KB
rs1007683459 -- 10,439,879(+) CACAC(A/G)CACAC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR5689 Gene

Variant ID Type Subtype PubMed ID
esv2667708 CNV deletion 23128226
nsv1022072 CNV gain 25217958

Relevant External Links for MIR5689 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5689

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5689 Gene

Disorders for MIR5689 Gene

Relevant External Links for MIR5689

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5689

No disorders were found for MIR5689 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5689 Gene

Publications for MIR5689 Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A. … Wang Y. (PLoS ONE 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5689 Gene

Sources for MIR5689 Gene

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