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Aliases for MIR5687 Gene

Subcategory (RNA class) for MIR5687 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5687 Gene

  • MicroRNA 5687 2 3 5
  • Hsa-Mir-5687 3

External Ids for MIR5687 Gene

Previous GeneCards Identifiers for MIR5687 Gene

  • GC05U901585
  • GC05M054806

Summaries for MIR5687 Gene

Entrez Gene Summary for MIR5687 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5687 Gene

MIR5687 (MicroRNA 5687) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5687 Gene

Genomics for MIR5687 Gene

Regulatory Elements for MIR5687 Gene

Enhancers for MIR5687 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G055508 0.8 ENCODE dbSUPER 0.7 -1.0 -1044 2.6 OSR2 CTCF SCRT1 HNF4A RAD21 PRDM1 NR2F2 RNF138P1 PLPP1 MIR5687
GH05G055516 1 ENCODE dbSUPER 0.4 -11.3 -11313 6.8 KLF1 KLF17 ZNF2 ZNF507 ZNF664 CTBP1 GATA3 PATZ1 SCRT2 KLF7 CCNO RNF138P1 MIR5687
GH05G055489 0.8 dbSUPER 0.4 +19.1 19136 0.4 CTCF ATF1 IRF2 PKNOX1 CREB3L1 TAL1 MAX RAD21 TCF12 ZNF316 ENSG00000279883 MIR5687
GH05G055494 0.7 ENCODE dbSUPER 0.4 +14.1 14068 0.9 CTCF HNF4A RAD21 RNF138P1 PLPP1 MIR5687 ENSG00000279883
GH05G055483 0.9 ENCODE dbSUPER 0.3 +24.2 24220 1.6 MAX CHD7 ZNF644 ATF2 JUND HDAC2 POU5F1 MAFK RNF138P1 ENSG00000279883 MIR5687
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5687 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5687 Gene

Chromosome:
5
Start:
55,508,850 bp from pter
End:
55,508,926 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR5687 Gene

Genes around MIR5687 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5687 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5687 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5687 Gene

Proteins for MIR5687 Gene

Post-translational modifications for MIR5687 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5687 Gene

Domains & Families for MIR5687 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5687 Gene

Function for MIR5687 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5687 Gene

Localization for MIR5687 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5687 Gene

Pathways & Interactions for MIR5687 Gene

SuperPathways for MIR5687 Gene

No Data Available

Interacting Proteins for MIR5687 Gene

Gene Ontology (GO) - Biological Process for MIR5687 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5687 Gene

Drugs & Compounds for MIR5687 Gene

No Compound Related Data Available

Transcripts for MIR5687 Gene

mRNA/cDNA for MIR5687 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5687 Gene

No ASD Table

Relevant External Links for MIR5687 Gene

GeneLoc Exon Structure for
MIR5687
ECgene alternative splicing isoforms for
MIR5687

Expression for MIR5687 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5687 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5687 Gene:

MIR5687
genes like me logo Genes that share expression patterns with MIR5687: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5687 Gene

Orthologs for MIR5687 Gene

Evolution for MIR5687 Gene

ENSEMBL:
Gene Tree for MIR5687 (if available)
TreeFam:
Gene Tree for MIR5687 (if available)

No data available for Orthologs for MIR5687 Gene

Paralogs for MIR5687 Gene

No data available for Paralogs for MIR5687 Gene

Variants for MIR5687 Gene

Sequence variations from dbSNP and Humsavar for MIR5687 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000977386 -- 55,510,403(+) ACTAC(A/G)AAGAA intron-variant, upstream-variant-2KB
rs1005677805 -- 55,509,469(+) ATTAT(A/G)AAAAG intron-variant, upstream-variant-2KB
rs1005847907 -- 55,508,842(+) CTCAG(G/T)ATTCC intron-variant, downstream-variant-500B
rs1007521357 -- 55,510,594(+) TCATA(C/T)CTATT intron-variant, upstream-variant-2KB
rs1010401492 -- 55,510,608(+) AACCT(C/T)TTGAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5687 Gene

Variant ID Type Subtype PubMed ID
nsv830304 CNV gain+loss 17160897

Relevant External Links for MIR5687 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5687

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5687 Gene

Disorders for MIR5687 Gene

Relevant External Links for MIR5687

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5687

No disorders were found for MIR5687 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5687 Gene

Publications for MIR5687 Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A. … Wang Y. (PLoS ONE 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5687 Gene

Sources for MIR5687 Gene

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