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Aliases for MIR5681B Gene

Subcategory (RNA class) for MIR5681B Gene


Quality Score for this RNA gene is


Aliases for MIR5681B Gene

  • MicroRNA 5681b 2 3 5
  • Hsa-Mir-5681b 3

External Ids for MIR5681B Gene

Previous GeneCards Identifiers for MIR5681B Gene

  • GC08U901581
  • GC08P075464

Summaries for MIR5681B Gene

Entrez Gene Summary for MIR5681B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5681B Gene

MIR5681B (MicroRNA 5681b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5681B Gene

Genomics for MIR5681B Gene

Regulatory Elements for MIR5681B Gene

Enhancers for MIR5681B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F074554 0.5 ENCODE 0.4 -6.6 -6581 1.1 IKZF1 MIR2052HG MIR5681B
GH08F074576 0.4 ENCODE 0.3 -27.9 -27912 0.3 MBD2 GATA3 RFX1 DPF2 MIR2052HG MIR5681B
GH08F074581 0.2 ENCODE 0.3 -33.1 -33146 0.9 JUND JUN MIR2052HG MIR5681B
GH08F074589 0.4 ENCODE 0.2 -41.3 -41312 0.2 MIR2052HG MIR5681B
GH08F074590 0.2 ENCODE 0.2 -41.6 -41572 0.2 MIR2052HG MIR5681B
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR5681B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5681B Gene

74,548,550 bp from pter
74,548,609 bp from pter
60 bases
Minus strand

Genomic View for MIR5681B Gene

Genes around MIR5681B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5681B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5681B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5681B Gene

ORGUL Member Location for MIR5681B Gene

ORGUL Member Location for MIR5681B gene

Proteins for MIR5681B Gene

Post-translational modifications for MIR5681B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5681B Gene

Domains & Families for MIR5681B Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5681B Gene

Function for MIR5681B Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5681B Gene

Localization for MIR5681B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5681B Gene

Pathways & Interactions for MIR5681B Gene

SuperPathways for MIR5681B Gene

No Data Available

Interacting Proteins for MIR5681B Gene

Gene Ontology (GO) - Biological Process for MIR5681B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5681B Gene

Transcripts for MIR5681B Gene

mRNA/cDNA for MIR5681B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5681B Gene

No ASD Table

Relevant External Links for MIR5681B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5681B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5681B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5681B Gene

Orthologs for MIR5681B Gene

Evolution for MIR5681B Gene

Gene Tree for MIR5681B (if available)
Gene Tree for MIR5681B (if available)

No data available for Orthologs for MIR5681B Gene

Paralogs for MIR5681B Gene

No data available for Paralogs for MIR5681B Gene

Variants for MIR5681B Gene

Sequence variations from dbSNP and Humsavar for MIR5681B Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs111293293 -- 74,548,550(+) TTTTG(-/G/GA)AAGAG nc-transcript-variant
rs111728443 -- 74,548,551(+) TTTTG(A/G)AGAGT nc-transcript-variant
rs112551903 -- 74,550,185(+) AAACT(A/G)CAATT upstream-variant-2KB
rs113601970 -- 74,550,551(+) CTCTT(A/C/T)TTTTT upstream-variant-2KB
rs113878947 -- 74,549,490(+) AGTAA(-/T)TTTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5681B Gene

Variant ID Type Subtype PubMed ID
esv3617664 CNV gain 21293372
nsv1120167 OTHER inversion 24896259

Relevant External Links for MIR5681B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5681B Gene

Disorders for MIR5681B Gene

Relevant External Links for MIR5681B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5681B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5681B Gene

Publications for MIR5681B Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A. … Wang Y. (PLoS ONE 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5681B Gene

Sources for MIR5681B Gene

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