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Aliases for MIR5681A Gene

Subcategory (RNA class) for MIR5681A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5681A Gene

  • MicroRNA 5681a 2 3 5
  • Hsa-Mir-5681a 3

External Ids for MIR5681A Gene

Previous GeneCards Identifiers for MIR5681A Gene

  • GC08U901589
  • GC08P075463

Summaries for MIR5681A Gene

Entrez Gene Summary for MIR5681A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5681A Gene

MIR5681A (MicroRNA 5681a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5681A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5681A Gene

Genomics for MIR5681A Gene

GeneHancer (GH) Regulatory Elements for MIR5681A Gene

Promoters and enhancers for MIR5681A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I074546 Enhancer 0.2 ENCODE 550.8 -1.1 -1143 1.3 MIR5681A MIR5681B GC08P074448
GH08I074505 Enhancer 0.5 FANTOM5 0.3 -42.4 -42418 0.4 FOSL1 IRF2 NFYC NR2C2 MIR5681A GC08P074448
GH08I074461 Enhancer 0.2 ENCODE 0.2 -86.8 -86782 0.2 GC08P074448 MIR5681A GDAP1
GH08I074464 Enhancer 0.2 ENCODE 0.2 -84.1 -84062 0.2 GC08P074448 MIR5681A GDAP1
GH08I074492 Enhancer 0.2 ENCODE 0.2 -55.5 -55502 0.2 GC08P074448 MIR5681A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5681A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5681A Gene

Genomic Locations for MIR5681A Gene
chr8:74,548,543-74,548,617
(GRCh38/hg38)
Size:
75 bases
Orientation:
Plus strand
chr8:75,460,778-75,460,852
(GRCh37/hg19)

Genomic View for MIR5681A Gene

Genes around MIR5681A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5681A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5681A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5681A Gene

Proteins for MIR5681A Gene

Post-translational modifications for MIR5681A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5681A Gene

Domains & Families for MIR5681A Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5681A Gene

Function for MIR5681A Gene

Phenotypes From GWAS Catalog for MIR5681A Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5681A Gene

Localization for MIR5681A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5681A Gene

Pathways & Interactions for MIR5681A Gene

SuperPathways for MIR5681A Gene

No Data Available

Interacting Proteins for MIR5681A Gene

Gene Ontology (GO) - Biological Process for MIR5681A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5681A Gene

Drugs & Compounds for MIR5681A Gene

No Compound Related Data Available

Transcripts for MIR5681A Gene

mRNA/cDNA for MIR5681A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5681A Gene

No ASD Table

Relevant External Links for MIR5681A Gene

GeneLoc Exon Structure for
MIR5681A
ECgene alternative splicing isoforms for
MIR5681A

Expression for MIR5681A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5681A Gene:

MIR5681A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5681A Gene

Orthologs for MIR5681A Gene

Evolution for MIR5681A Gene

ENSEMBL:
Gene Tree for MIR5681A (if available)
TreeFam:
Gene Tree for MIR5681A (if available)

No data available for Orthologs for MIR5681A Gene

Paralogs for MIR5681A Gene

No data available for Paralogs for MIR5681A Gene

Variants for MIR5681A Gene

Sequence variations from dbSNP and Humsavar for MIR5681A Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000187423 -- 74,548,905(+) T/C downstream_transcript_variant
rs1000538320 -- 74,546,739(+) C/T upstream_transcript_variant
rs1000644138 -- 74,548,409(+) C/T upstream_transcript_variant
rs1000909656 -- 74,546,972(+) A/G upstream_transcript_variant
rs1002177787 -- 74,548,844(+) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5681A Gene

Variant ID Type Subtype PubMed ID
esv3617664 CNV gain 21293372
nsv1120167 OTHER inversion 24896259

Additional Variant Information for MIR5681A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5681A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5681A Gene

Disorders for MIR5681A Gene

Additional Disease Information for MIR5681A

No disorders were found for MIR5681A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5681A Gene

Publications for MIR5681A Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5681A Gene

Sources for MIR5681A Gene

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