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Aliases for MIR5681A Gene

Subcategory (RNA class) for MIR5681A Gene


Quality Score for this RNA gene is


Aliases for MIR5681A Gene

  • MicroRNA 5681a 2 3 5
  • Hsa-Mir-5681a 3

External Ids for MIR5681A Gene

Previous GeneCards Identifiers for MIR5681A Gene

  • GC08U901589
  • GC08P075463

Summaries for MIR5681A Gene

Entrez Gene Summary for MIR5681A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5681A Gene

MIR5681A (MicroRNA 5681a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5681A Gene

Genomics for MIR5681A Gene

Regulatory Elements for MIR5681A Gene

Enhancers for MIR5681A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F074546 0.7 ENCODE 0.8 -1.1 -1143 1.3 MIR5681A GC08P074448
GH08F074505 0.5 FANTOM5 0.2 -42.4 -42419 0.4 IRF2 ATF3 NFYC IRF1 NR2C2 MIR5681A GC08P074448
GH08F074461 0.6 ENCODE 0.2 -86.8 -86783 0.2 GC08P074448 MIR5681A
GH08F074464 0.2 ENCODE 0.2 -84.1 -84063 0.2 GC08P074448 MIR5681A
GH08F074492 0.2 ENCODE 0.2 -55.5 -55503 0.2 EZH2 GC08P074448 MIR5681A
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR5681A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5681A Gene

74,548,543 bp from pter
74,548,617 bp from pter
75 bases
Plus strand

Genomic View for MIR5681A Gene

Genes around MIR5681A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5681A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5681A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5681A Gene

Proteins for MIR5681A Gene

Post-translational modifications for MIR5681A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5681A Gene

Domains & Families for MIR5681A Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5681A Gene

Function for MIR5681A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5681A Gene

Localization for MIR5681A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5681A Gene

Pathways & Interactions for MIR5681A Gene

SuperPathways for MIR5681A Gene

No Data Available

Interacting Proteins for MIR5681A Gene

Gene Ontology (GO) - Biological Process for MIR5681A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5681A Gene

Transcripts for MIR5681A Gene

mRNA/cDNA for MIR5681A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5681A Gene

No ASD Table

Relevant External Links for MIR5681A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5681A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5681A Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5681A Gene

Orthologs for MIR5681A Gene

Evolution for MIR5681A Gene

Gene Tree for MIR5681A (if available)
Gene Tree for MIR5681A (if available)

No data available for Orthologs for MIR5681A Gene

Paralogs for MIR5681A Gene

No data available for Paralogs for MIR5681A Gene

Variants for MIR5681A Gene

Sequence variations from dbSNP and Humsavar for MIR5681A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs111293293 -- 74,548,550(+) TTTTG(-/G/GA)AAGAG nc-transcript-variant
rs111728443 -- 74,548,551(+) TTTTG(A/G)AGAGT nc-transcript-variant
rs114214329 -- 74,546,551(+) ATCTA(A/C)AAAAG upstream-variant-2KB
rs118028309 -- 74,548,420(+) TCTGT(G/T)AGAGA downstream-variant-500B, upstream-variant-2KB
rs118118042 -- 74,547,317(+) CCCAG(C/T)AGTCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5681A Gene

Variant ID Type Subtype PubMed ID
esv3617664 CNV gain 21293372
nsv1120167 OTHER inversion 24896259

Relevant External Links for MIR5681A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5681A Gene

Disorders for MIR5681A Gene

Relevant External Links for MIR5681A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5681A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5681A Gene

Publications for MIR5681A Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A. … Wang Y. (PLoS ONE 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5681A Gene

Sources for MIR5681A Gene

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