Aliases for MIR568 Gene
Subcategory (RNA class) for MIR568 Gene
miRNA
Quality Score for this RNA gene is
3
External Ids for MIR568 Gene
- HGNC: 32824
- Entrez Gene: 693153
- Ensembl: ENSG00000259976
- miRBase: hsa-mir-568
Previous HGNC Symbols for MIR568 Gene
- MIRN568
Previous GeneCards Identifiers for MIR568 Gene
- GC03U901158
- GC03M115520
- GC03M114035
Summaries for MIR568 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR568 Gene
MIR568 (MicroRNA 568) is an RNA Gene, and is affiliated with the miRNA class.
No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR568 Gene
Genomics for MIR568 Gene
Regulatory Elements for MIR568 Gene
Enhancers for MIR568 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH03F113694 | 1.4 | FANTOM5 ENCODE | 9.7 | +632.5 | 632541 | 4.8 | HDGF PKNOX1 ATF1 ARID4B SIN3A YBX1 DMAP1 ZNF48 YY1 GLIS2 | NAA50 USF3 QTRT2 MIR568 SIDT1 ATP6V1A GC03P113719 |
| GH03F115098 | 0.9 | ENCODE | 9.7 | -770.3 | -770331 | 3.1 | TBP PKNOX1 ZFP64 ZNF48 RAD21 YY1 ZNF302 ZNF366 SCRT2 ZNF680 | ZBTB20 MIR568 ZBTB20-AS4 GC03P115085 |
| GH03F114332 | 0.6 | Ensembl ENCODE | 0.8 | -3.8 | -3814 | 2.1 | HMBOX1 | MIR568 ZBTB20-AS1 |
| GH03F114338 | 0.9 | ENCODE | 0.4 | -9.0 | -8996 | 1.1 | ELF3 HDAC1 ATF1 ARNT SIN3A DMAP1 YY1 ZEB1 ZNF335 SCRT2 | MIR568 ZBTB20-AS1 |
| GH03F114319 | 0.9 | Ensembl ENCODE | 0.4 | +10.1 | 10077 | 0.3 | ZNF146 HLF JUN TEAD4 CEBPB MAX MNT JUND FOS | GC03M114317 MIR568 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MIR568 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MIR568 Gene
- Chromosome:
- 3
- Start:
- 114,314,501 bp from pter
- End:
- 114,329,714 bp from pter
- Size:
- 15,214 bases
- Orientation:
- Minus strand
Genomic View for MIR568 Gene
Genes around MIR568 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q13.31 by Ensembl
- 3q13.31 by Entrez Gene
- 3q13.31 by HGNC
MIR568 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR568 Gene
Proteins for MIR568 Gene
Post-translational modifications for MIR568 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR568
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR568
- Origene Custom Protein Services for MIR568
- Search GeneTex for Proteins for MIR568
Assay Products
No data available for DME Specific Peptides for MIR568 Gene
Domains & Families for MIR568 Gene
Gene Families for MIR568 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR568 Gene
Function for MIR568 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR568
-
- Search ViGene Biosciences for MIR568
CRISPR Products
- Browse CRISPR knockouts for MIR568
miRNA Products
- Search ViGene Biosciences for MIR568
-
Origene geneexpression products in human, mouse, rat for MIR568
- Browse OriGene miRNA Products For MIR568
Inhibitory RNA Products
- Search ViGene Biosciences for MIR568
Clone Products
- GenScript: Custom all cDNA clones Services for MIR568
- VectorBuilder custom plasmid, inducible vectors for MIR568
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR568
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for MIR568
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR568 Gene
Localization for MIR568 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR568 Gene
Transcripts for MIR568 Gene
mRNA/cDNA for MIR568 Gene
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR568
miRNA Products
- Search ViGene Biosciences for MIR568
-
Origene geneexpression products in human, mouse, rat for MIR568
- Browse OriGene miRNA Products For MIR568
Inhibitory RNA Products
- Search ViGene Biosciences for MIR568
Clone Products
- GenScript: Custom all cDNA clones Services for MIR568
- VectorBuilder custom plasmid, inducible vectors for MIR568
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR568
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for MIR568 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR568 Gene:
MIR568Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR568 Gene
Orthologs for MIR568 Gene
No data available for Orthologs for MIR568 Gene
Paralogs for MIR568 Gene
No data available for Paralogs for MIR568 Gene
Variants for MIR568 Gene
| SNP ID | Clin | Chr 03 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1045054 | -- | 114,316,676(-) | ACTTT(A/T)AAAAA | nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime | |
| rs111976878 | -- | 114,316,215(+) | GCATT(C/T)GCATC | nc-transcript-variant, downstream-variant-500B, utr-variant-3-prime | |
| rs113566951 | -- | 114,317,801(+) | AGTTT(C/G)TGTGT | nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime | |
| rs114906842 | -- | 114,318,531(+) | CCCAC(C/T)GAGAG | nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime | |
| rs116606580 | -- | 114,316,777(+) | AGAAA(A/C)CTGGG | nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime |
Relevant External Links for MIR568 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR568
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR568 Gene
Disorders for MIR568 Gene
Relevant External Links for MIR568
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR568
No disorders were found for MIR568 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR568 Gene
Publications for MIR568 Gene
- Mutational Analysis of Pre-miR-184 and hsa-mir-568 in Greek Patients With Sporadic Keratoconus. (PMID: 26845316) Moschos M.M. … Gazouli M. (Cornea 2016) 3 64
- Mechanical stress induces pre-B-cell colony-enhancing factor/NAMPT expression via epigenetic regulation by miR-374a and miR-568 in human lung endothelium. (PMID: 24053186) Adyshev D.M. … Garcia J.G. (Am. J. Respir. Cell Mol. Biol. 2014) 3 64
- MiR-568 inhibits the activation and function of CD4a8_ T cells and Treg cells by targeting NFAT5. (PMID: 24355664) Li W. … Yang A.G. (Int. Immunol. 2014) 3 64
- Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis. (PMID: 25311085) Li J.T. … Yang A.G. (Breast Cancer Res. 2014) 3 64
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
Products for MIR568 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse ELISpot/FluoroSpot Kits and Development Modules
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- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
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- Browse OriGene Antibodies
- Custom Antibody Services
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR568
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- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR568
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Origene geneexpression products in human, mouse, rat for MIR568
- Browse OriGene miRNA Products For MIR568
- GenScript: Custom all cDNA clones Services for MIR568
- GenScript Custom Purified and Recombinant Proteins Services for MIR568
- GenScript Custom Assay Services for MIR568
- GenScript Custom overexpressing Cell Line Services for MIR568
- Browse GenScript CRISPR for MIR568
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search ViGene Biosciences for MIR568
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR568
- VectorBuilder custom plasmid, inducible vectors for MIR568
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR568
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR568 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
- (123) NIH Rare Diseases
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- (135) Gene Damage Index
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- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab