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Aliases for MIR562 Gene

Subcategory (RNA class) for MIR562 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR562 Gene

  • MicroRNA 562 2 3 5
  • Hsa-Mir-562 3
  • MIRN562 3

External Ids for MIR562 Gene

ORGUL Members for MIR562 Gene

Previous HGNC Symbols for MIR562 Gene

  • MIRN562

Previous GeneCards Identifiers for MIR562 Gene

  • GC02P232746
  • GC02P233037

Summaries for MIR562 Gene

Entrez Gene Summary for MIR562 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR562 Gene

MIR562 (MicroRNA 562) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR562 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR562 Gene

Genomics for MIR562 Gene

Regulatory Elements for MIR562 Gene

Enhancers for MIR562 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H232204 0.9 Ensembl ENCODE 11.5 +31.9 31907 0 SOX5 SOX13 TEAD1 HLF DMAP1 ZNF7 NFIL3 NR2F6 BCL6 HNF4A MIR562 DIS3L2 ENSG00000227033 MIR1471 GC02P232173 LOC730069
GH02H232137 0.8 Ensembl ENCODE 11.6 -34.7 -34723 0 ZNF316 MAFG EMSY MAFK MIR562 NPPC MIR1471 GC02P232174 ENSG00000227033
GH02H232307 0.6 ENCODE dbSUPER 10.6 +137.3 137287 4 POLR2A NPPC MIR562 ENSG00000251485 EIF4E2 LOC730069 GC02P232173
GH02H232306 0.5 ENCODE dbSUPER 10.6 +134.4 134414 0 NPPC MIR1471 MIR562 LOC730069 GC02P232173
GH02H232075 0.4 ENCODE 10.9 -97.4 -97408 0 CEBPB CEBPG DIS3L2 MIR562 MIR1471 ENSG00000227033 GC02P232174
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR562 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR562 Gene

Chromosome:
2
Start:
232,172,653 bp from pter
End:
232,172,747 bp from pter
Size:
95 bases
Orientation:
Plus strand

Genomic View for MIR562 Gene

Genes around MIR562 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR562 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR562 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR562 Gene

Proteins for MIR562 Gene

Post-translational modifications for MIR562 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR562 Gene

Domains & Families for MIR562 Gene

Gene Families for MIR562 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR562: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR562 Gene

Function for MIR562 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR562
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR562 Gene

Localization for MIR562 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR562 Gene

Pathways & Interactions for MIR562 Gene

SuperPathways for MIR562 Gene

No Data Available

Interacting Proteins for MIR562 Gene

Gene Ontology (GO) - Biological Process for MIR562 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR562 Gene

Drugs & Compounds for MIR562 Gene

No Compound Related Data Available

Transcripts for MIR562 Gene

mRNA/cDNA for MIR562 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR562
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR562 Gene

No ASD Table

Relevant External Links for MIR562 Gene

GeneLoc Exon Structure for
MIR562
ECgene alternative splicing isoforms for
MIR562

Expression for MIR562 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR562 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR562 Gene:

MIR562
genes like me logo Genes that share expression patterns with MIR562: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR562 Gene

Orthologs for MIR562 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR562 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-562 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-562 34
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 34
  • 68 (a)
ManyToMany
Species where no ortholog for MIR562 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR562 Gene

ENSEMBL:
Gene Tree for MIR562 (if available)
TreeFam:
Gene Tree for MIR562 (if available)

Paralogs for MIR562 Gene

No data available for Paralogs for MIR562 Gene

Variants for MIR562 Gene

Sequence variations from dbSNP and Humsavar for MIR562 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1003799605 -- 232,170,900(+) ATATA(A/G)TACTA intron-variant, upstream-variant-2KB
rs1005086998 -- 232,171,094(+) GGCCT(A/G)GCTAG intron-variant, upstream-variant-2KB
rs1005731369 -- 232,171,051(+) TAGCA(C/T)TGAAG intron-variant, upstream-variant-2KB
rs1006076740 -- 232,172,744(+) TGTGG(C/T)AATGT intron-variant, nc-transcript-variant
rs1006156962 -- 232,173,026(+) CAAAC(A/G)CTGGT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR562 Gene

Variant ID Type Subtype PubMed ID
esv3594640 CNV loss 21293372
nsv3209 CNV deletion 18451855

Relevant External Links for MIR562 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR562

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR562 Gene

Disorders for MIR562 Gene

Relevant External Links for MIR562

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR562

No disorders were found for MIR562 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR562 Gene

Publications for MIR562 Gene

  1. Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells. (PMID: 25536365) Anbalagan D … Lim LH (PloS one 2014) 3 60
  2. Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562. (PMID: 19789318) Drake KM … Aldred MA (Clinical cancer research : an official journal of the American Association for Cancer Research 2009) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60
  4. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 60

Products for MIR562 Gene

Sources for MIR562 Gene

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