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Aliases for MIR561 Gene

Subcategory (RNA class) for MIR561 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR561 Gene

  • MicroRNA 561 2 3 5
  • Hsa-Mir-561 3
  • Mir-561 3
  • MIRN561 3

External Ids for MIR561 Gene

ORGUL Members for MIR561 Gene

Previous HGNC Symbols for MIR561 Gene

  • MIRN561

Previous GeneCards Identifiers for MIR561 Gene

  • GC02P188871
  • GC02P189162

Summaries for MIR561 Gene

Entrez Gene Summary for MIR561 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR561 Gene

MIR561 (MicroRNA 561) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR561 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR561 Gene

Genomics for MIR561 Gene

Regulatory Elements for MIR561 Gene

Enhancers for MIR561 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H188326 1.1 Ensembl ENCODE 11.5 +29.4 29406 1 HDAC1 PKNOX1 ATF1 ARNT ZNF766 SCRT2 RCOR1 ATF7 CREM ZNF592 MIR561 GULP1 LINC01090 GC02P188298
GH02H188321 0.9 Ensembl ENCODE dbSUPER 11.9 +25.4 25350 3 GATA3 JUN GULP1 MIR561 LINC01090 GC02P188298
GH02H188318 0.8 ENCODE dbSUPER 11.9 +22.0 22024 2 CTBP1 FEZF1 ZNF843 TCF7L2 ZNF18 TRIM28 MIR561 GULP1 LINC01090 GC02P188298
GH02H188198 0.8 Ensembl ENCODE 10.7 -97.7 -97695 1 GATA3 JUND POLR2A FOS PRDM1 TCF7L2 GULP1 MIR561 LINC01090 LOC729141 GC02P187827 GC02P187828 GC02P187829 PIR31110
GH02H188317 0.7 ENCODE dbSUPER 11.3 +20.5 20490 0 ZNF843 TCF7L2 ZNF18 MIR561 GULP1 LINC01090 DIRC1 GC02P188298
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR561 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR561 Gene

Chromosome:
2
Start:
188,297,492 bp from pter
End:
188,297,588 bp from pter
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR561 Gene

Genes around MIR561 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR561 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR561 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR561 Gene

Proteins for MIR561 Gene

Post-translational modifications for MIR561 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR561 Gene

Domains & Families for MIR561 Gene

Gene Families for MIR561 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR561: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR561 Gene

Function for MIR561 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR561
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR561 Gene

Localization for MIR561 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR561 Gene

Pathways & Interactions for MIR561 Gene

SuperPathways for MIR561 Gene

No Data Available

Interacting Proteins for MIR561 Gene

Gene Ontology (GO) - Biological Process for MIR561 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR561 Gene

Drugs & Compounds for MIR561 Gene

No Compound Related Data Available

Transcripts for MIR561 Gene

mRNA/cDNA for MIR561 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR561
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR561 Gene

No ASD Table

Relevant External Links for MIR561 Gene

GeneLoc Exon Structure for
MIR561
ECgene alternative splicing isoforms for
MIR561

Expression for MIR561 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR561 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR561 Gene:

MIR561
genes like me logo Genes that share expression patterns with MIR561: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR561 Gene

Orthologs for MIR561 Gene

Evolution for MIR561 Gene

ENSEMBL:
Gene Tree for MIR561 (if available)
TreeFam:
Gene Tree for MIR561 (if available)

No data available for Orthologs for MIR561 Gene

Paralogs for MIR561 Gene

No data available for Paralogs for MIR561 Gene

Variants for MIR561 Gene

Sequence variations from dbSNP and Humsavar for MIR561 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000887752 -- 188,296,352(+) TGCTT(A/G)TACTG intron-variant, upstream-variant-2KB
rs1002193023 -- 188,297,752(+) ATGAG(A/G)TGATA intron-variant, downstream-variant-500B
rs1004391352 -- 188,297,763(+) ACTAT(G/T)GTTCT intron-variant, downstream-variant-500B
rs1005187793 -- 188,296,695(+) ATGGC(-/T)TTTTA intron-variant, upstream-variant-2KB
rs1008603440 -- 188,297,327(+) CATGT(A/G)CAGTT intron-variant, upstream-variant-2KB

Relevant External Links for MIR561 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR561

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR561 Gene

Disorders for MIR561 Gene

Relevant External Links for MIR561

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR561

No disorders were found for MIR561 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR561 Gene

Publications for MIR561 Gene

  1. Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ≤ 55 years. (PMID: 24166930) Guan X … Liu Z (Molecular carcinogenesis 2015) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60
  5. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 60

Products for MIR561 Gene

Sources for MIR561 Gene

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