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Aliases for MIR5591 Gene

Subcategory (RNA class) for MIR5591 Gene


Quality Score for this RNA gene is


Aliases for MIR5591 Gene

  • MicroRNA 5591 2 3 5
  • Hsa-Mir-5591 3

External Ids for MIR5591 Gene

Previous GeneCards Identifiers for MIR5591 Gene

  • GC04U901525

Summaries for MIR5591 Gene

Entrez Gene Summary for MIR5591 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5591 Gene

MIR5591 (MicroRNA 5591) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5591 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5591 Gene

Genomics for MIR5591 Gene

Regulatory Elements for MIR5591 Gene

Enhancers for MIR5591 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H039406 0.9 Ensembl 0.7 -5.0 -4994 0.6 ATF1 ARID4B SIN3A YY1 MXD4 REST MIER2 KAT8 NFIL3 MIER3 KLB MIR5591
GH04H039415 0.8 ENCODE 0.7 +4.0 3986 0.2 SOX13 SAP130 MAX CEBPG THRB RAD21 RARA NR2F6 THAP11 GATAD2A MIR5591 GC04P039441
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5591 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5591 Gene

Genomic Locations for MIR5591 Gene
65 bases
Plus strand

Genomic View for MIR5591 Gene

Genes around MIR5591 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5591 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5591 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5591 Gene

Proteins for MIR5591 Gene

Post-translational modifications for MIR5591 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5591 Gene

Domains & Families for MIR5591 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5591 Gene

Function for MIR5591 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5591 Gene

Localization for MIR5591 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5591 Gene

Pathways & Interactions for MIR5591 Gene

SuperPathways for MIR5591 Gene

No Data Available

Interacting Proteins for MIR5591 Gene

Gene Ontology (GO) - Biological Process for MIR5591 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5591 Gene

Drugs & Compounds for MIR5591 Gene

No Compound Related Data Available

Transcripts for MIR5591 Gene

mRNA/cDNA for MIR5591 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5591 Gene

No ASD Table

Relevant External Links for MIR5591 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5591 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5591 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5591 Gene

Orthologs for MIR5591 Gene

Evolution for MIR5591 Gene

Gene Tree for MIR5591 (if available)
Gene Tree for MIR5591 (if available)

No data available for Orthologs for MIR5591 Gene

Paralogs for MIR5591 Gene

No data available for Paralogs for MIR5591 Gene

Variants for MIR5591 Gene

Sequence variations from dbSNP and Humsavar for MIR5591 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1003128480 -- 39,412,055(+) GGAGA(C/T)TCAGA intron-variant, downstream-variant-500B
rs1005488514 -- 39,411,336(+) GTTTT(G/T)ATTTT intron-variant, upstream-variant-2KB
rs1005952495 -- 39,410,144(+) AAAGT(C/T)ATTAC intron-variant, upstream-variant-2KB
rs1009395688 -- 39,411,205(+) CACCA(C/T)GCCTG intron-variant, upstream-variant-2KB
rs1011019126 -- 39,410,882(+) GAAAT(A/G)TTCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5591 Gene

Variant ID Type Subtype PubMed ID
esv3600279 CNV gain 21293372

Relevant External Links for MIR5591 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5591 Gene

Disorders for MIR5591 Gene

Relevant External Links for MIR5591

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5591 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5591 Gene

Publications for MIR5591 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR5591 Gene

Sources for MIR5591 Gene

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