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Aliases for MIR5591 Gene

Subcategory (RNA class) for MIR5591 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5591 Gene

  • MicroRNA 5591 2 3 5
  • Hsa-Mir-5591 3

External Ids for MIR5591 Gene

Previous GeneCards Identifiers for MIR5591 Gene

  • GC04U901525

Summaries for MIR5591 Gene

Entrez Gene Summary for MIR5591 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5591 Gene

MIR5591 (MicroRNA 5591) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5591 Gene

Genomics for MIR5591 Gene

Regulatory Elements for MIR5591 Gene

Enhancers for MIR5591 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F039406 0.9 Ensembl 0.8 -5.0 -4986 0.6 ELF3 TBP ATF1 ARID4B RAD21 RARA YY1 GATA4 CREM MIXL1 KLB MIR5591
GH04F039415 0.8 ENCODE 0.8 +4.0 3986 0.2 SOX13 SAP130 CEBPG THRB RAD21 RARA NR2F6 THAP11 GATAD2A TEAD1 MIR5591 GC04P039441
GH04F039418 0.2 Ensembl 0.4 +6.8 6791 0.2 RFC1 RNU6-32P ENSG00000249685 LOC105374417 RPL9 MIR5591 GC04P039441
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5591 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5591 Gene

Chromosome:
4
Start:
39,411,910 bp from pter
End:
39,411,974 bp from pter
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR5591 Gene

Genes around MIR5591 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5591 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5591 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5591 Gene

Proteins for MIR5591 Gene

Post-translational modifications for MIR5591 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5591 Gene

Domains & Families for MIR5591 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5591 Gene

Function for MIR5591 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5591 Gene

Localization for MIR5591 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5591 Gene

Pathways & Interactions for MIR5591 Gene

SuperPathways for MIR5591 Gene

No Data Available

Interacting Proteins for MIR5591 Gene

Gene Ontology (GO) - Biological Process for MIR5591 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5591 Gene

Transcripts for MIR5591 Gene

mRNA/cDNA for MIR5591 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5591 Gene

No ASD Table

Relevant External Links for MIR5591 Gene

GeneLoc Exon Structure for
MIR5591
ECgene alternative splicing isoforms for
MIR5591

Expression for MIR5591 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5591 Gene:

MIR5591
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5591 Gene

Orthologs for MIR5591 Gene

Evolution for MIR5591 Gene

ENSEMBL:
Gene Tree for MIR5591 (if available)
TreeFam:
Gene Tree for MIR5591 (if available)

No data available for Orthologs for MIR5591 Gene

Paralogs for MIR5591 Gene

No data available for Paralogs for MIR5591 Gene

Variants for MIR5591 Gene

Sequence variations from dbSNP and Humsavar for MIR5591 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs112447569 -- 39,411,776(+) AGCCT(A/G)TGAGT intron-variant, upstream-variant-2KB
rs112683257 -- 39,411,638(+) CCTCA(A/G)CCTCC intron-variant, upstream-variant-2KB
rs114244180 -- 39,412,092(+) GATAA(A/G)AAAAC intron-variant, downstream-variant-500B
rs115201286 -- 39,412,087(+) TAAGG(G/T)ATAAA intron-variant, downstream-variant-500B
rs12233688 -- 39,411,290(+) AGCGC(C/T)CGGCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5591 Gene

Variant ID Type Subtype PubMed ID
esv3600279 CNV gain 21293372

Relevant External Links for MIR5591 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5591

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5591 Gene

Disorders for MIR5591 Gene

Relevant External Links for MIR5591

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5591

No disorders were found for MIR5591 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5591 Gene

Publications for MIR5591 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5591 Gene

Sources for MIR5591 Gene

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