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Aliases for MIR5589 Gene

Subcategory (RNA class) for MIR5589 Gene


Quality Score for this RNA gene is


Aliases for MIR5589 Gene

  • MicroRNA 5589 2 3 5
  • Hsa-Mir-5589 3

External Ids for MIR5589 Gene

Previous GeneCards Identifiers for MIR5589 Gene

  • GC19U901601
  • GC19P010154
  • GC19P010155

Summaries for MIR5589 Gene

Entrez Gene Summary for MIR5589 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5589 Gene

MIR5589 (MicroRNA 5589) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5589 Gene

Genomics for MIR5589 Gene

Regulatory Elements for MIR5589 Gene

Enhancers for MIR5589 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F010074 0.7 ENCODE 0.3 +36.1 36066 0.2 CTCF CBX3 USF1 MAX SIN3A RAD21 ZFHX2 CBX5 SMC3 TRIM24 C19orf66 MIR5589
GH19F010071 0.6 ENCODE 0.3 +32.9 32946 0.2 ATF3 GABPB1 ZBTB33 RAD21 NR2F2 YY1 ANGPTL6 PPAN PPAN-P2RY11 RDH8 COL5A3 EIF3G OLFM2 C19orf66 MIR5589
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR5589 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5589 Gene

10,038,354 bp from pter
10,038,413 bp from pter
60 bases
Plus strand

Genomic View for MIR5589 Gene

Genes around MIR5589 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5589 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5589 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5589 Gene

Proteins for MIR5589 Gene

Post-translational modifications for MIR5589 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5589 Gene

Domains & Families for MIR5589 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5589 Gene

Function for MIR5589 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5589 Gene

Localization for MIR5589 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5589 Gene

Pathways & Interactions for MIR5589 Gene

SuperPathways for MIR5589 Gene

No Data Available

Interacting Proteins for MIR5589 Gene

Gene Ontology (GO) - Biological Process for MIR5589 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5589 Gene

Transcripts for MIR5589 Gene

mRNA/cDNA for MIR5589 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5589 Gene

No ASD Table

Relevant External Links for MIR5589 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5589 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR5589 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5589 Gene:

genes like me logo Genes that share expression patterns with MIR5589: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5589 Gene

Orthologs for MIR5589 Gene

Evolution for MIR5589 Gene

Gene Tree for MIR5589 (if available)
Gene Tree for MIR5589 (if available)

No data available for Orthologs for MIR5589 Gene

Paralogs for MIR5589 Gene

No data available for Paralogs for MIR5589 Gene

Variants for MIR5589 Gene

Sequence variations from dbSNP and Humsavar for MIR5589 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10408877 -- 10,037,442(+) GAAGC(A/G)GATGG upstream-variant-2KB
rs10414528 -- 10,037,688(+) CCTAG(A/G)GTGGA upstream-variant-2KB
rs113973744 -- 10,037,279(+) TGAAC(A/G)TGGGA upstream-variant-2KB
rs114331487 -- 10,037,241(+) ATCCC(C/T)GCTAC upstream-variant-2KB
rs116796353 -- 10,038,396(+) TGCAC(A/G)TGGCA nc-transcript-variant

Relevant External Links for MIR5589 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5589 Gene

Disorders for MIR5589 Gene

Relevant External Links for MIR5589

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5589 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5589 Gene

Publications for MIR5589 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5589 Gene

Sources for MIR5589 Gene

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