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Aliases for MIR5584 Gene

Subcategory (RNA class) for MIR5584 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5584 Gene

  • MicroRNA 5584 2 3 5
  • Hsa-Mir-5584 3

External Ids for MIR5584 Gene

Previous GeneCards Identifiers for MIR5584 Gene

  • GC01U903365
  • GC01P045021

Summaries for MIR5584 Gene

Entrez Gene Summary for MIR5584 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5584 Gene

MIR5584 (MicroRNA 5584) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5584 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5584 Gene

Genomics for MIR5584 Gene

Regulatory Elements for MIR5584 Gene

Enhancers for MIR5584 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H044523 2.8 VISTA Ensembl ENCODE dbSUPER 0.3 -21.0 -20959 3 PKNOX1 TAL1 ETS1 TCF12 ZFHX2 ZNF316 POLR2A NCOR1 EGR2 SMARCE1 RNF220 ERI3 MIR5584
GH01H044541 1.1 Ensembl ENCODE dbSUPER 0.7 -2.3 -2298 2.4 CEBPB REST CEBPG ZIC2 ZNF766 POLR2A CTBP2 POU5F1 EZH2 RNF220 RNU6-369P ERI3 ATP6V0B MIR5584
GH01H044561 1.8 dbSUPER 0.3 +26.5 26513 21.5 CTCF ESRRA ZIC2 BCL11B RAD21 RFX5 ZNF664 CTBP1 GATA3 ZNF316 ERI3 RNU6-369P RNF220 DMAP1 RPS8 DPH2 BEST4 MIR5584 PIR47647
GH01H044531 1.3 ENCODE dbSUPER 0.4 -13.2 -13227 1.8 PKNOX1 ATF1 ARNT TCF12 ZNF121 CBX5 GATA2 ATF7 FOS RUNX3 TOE1 RNF220 ERI3 MIR5584
GH01H044483 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.2 -60.2 -60158 3.2 PKNOX1 ARNT FEZF1 ZNF2 ZNF766 FOS SMARCB1 MEF2D SMARCA4 ZNF585B DMAP1 RNF220 ZSWIM5 LOC101929609 RNU6-369P ARTN ERI3 KDM4A MUTYH PLK3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5584 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5584 Gene

Genomic Locations for MIR5584 Gene
chr1:44,545,493-44,545,552
(GRCh38/hg38)
Size:
60 bases
Orientation:
Plus strand
chr1:45,011,165-45,011,224
(GRCh37/hg19)

Genomic View for MIR5584 Gene

Genes around MIR5584 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5584 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5584 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5584 Gene

Proteins for MIR5584 Gene

Post-translational modifications for MIR5584 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5584 Gene

Domains & Families for MIR5584 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5584 Gene

Function for MIR5584 Gene

Phenotypes From GWAS Catalog for MIR5584 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5584 Gene

Localization for MIR5584 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5584 Gene

Pathways & Interactions for MIR5584 Gene

SuperPathways for MIR5584 Gene

No Data Available

Interacting Proteins for MIR5584 Gene

Gene Ontology (GO) - Biological Process for MIR5584 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5584 Gene

Drugs & Compounds for MIR5584 Gene

No Compound Related Data Available

Transcripts for MIR5584 Gene

mRNA/cDNA for MIR5584 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5584 Gene

No ASD Table

Relevant External Links for MIR5584 Gene

GeneLoc Exon Structure for
MIR5584
ECgene alternative splicing isoforms for
MIR5584

Expression for MIR5584 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5584 Gene:

MIR5584
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5584 Gene

Orthologs for MIR5584 Gene

Evolution for MIR5584 Gene

ENSEMBL:
Gene Tree for MIR5584 (if available)
TreeFam:
Gene Tree for MIR5584 (if available)

No data available for Orthologs for MIR5584 Gene

Paralogs for MIR5584 Gene

No data available for Paralogs for MIR5584 Gene

Variants for MIR5584 Gene

Sequence variations from dbSNP and Humsavar for MIR5584 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001276746 -- 44,544,601(+) ATAGA(A/G)CTGTC intron-variant, upstream-variant-2KB
rs1005047253 -- 44,545,614(+) GGGTG(A/G)GGGTG intron-variant, downstream-variant-500B
rs1005137030 -- 44,544,646(+) CCTTT(C/T)TGGAA intron-variant, upstream-variant-2KB
rs1006402942 -- 44,545,914(+) ACCAC(A/G)CCCGG intron-variant, downstream-variant-500B
rs1006859284 -- 44,545,183(+) CCTCA(C/G/T)AGAAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5584 Gene

Variant ID Type Subtype PubMed ID
nsv744 CNV insertion 18451855
nsv546144 CNV gain 21841781
nsv461395 CNV gain 19166990

Relevant External Links for MIR5584 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5584

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5584 Gene

Disorders for MIR5584 Gene

Relevant External Links for MIR5584

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5584

No disorders were found for MIR5584 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5584 Gene

Publications for MIR5584 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR5584 Gene

Sources for MIR5584 Gene

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