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Aliases for MIR5584 Gene

Subcategory (RNA class) for MIR5584 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5584 Gene

  • MicroRNA 5584 2 3 5
  • Hsa-Mir-5584 3

External Ids for MIR5584 Gene

Previous GeneCards Identifiers for MIR5584 Gene

  • GC01U903365
  • GC01P045021

Summaries for MIR5584 Gene

Entrez Gene Summary for MIR5584 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5584 Gene

MIR5584 (MicroRNA 5584) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5584 Gene

Genomics for MIR5584 Gene

Regulatory Elements for MIR5584 Gene

Enhancers for MIR5584 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G044541 1.2 Ensembl ENCODE dbSUPER 0.7 -2.3 -2298 2.4 CTCF CEBPG CHD7 ZIC2 ZNF766 POLR2A SCRT2 MAFK EZH2 CEBPB RNF220 RNU6-369P ERI3 ATP6V0B MIR5584
GH01G044523 2.8 VISTA Ensembl ENCODE dbSUPER 0.3 -21.0 -20959 3.0 PKNOX1 TAL1 TEAD4 ETS1 TCF12 ZFHX2 ZNF316 NCOR1 POLR2A EGR2 RNF220 ERI3 MIR5584
GH01G044545 1.1 dbSUPER 0.7 +0.8 779 0.7 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 ZNF2 YY1 ZNF766 ZNF143 ERI3 RNU6-369P RNF220 MIR5584 PIR47647
GH01G044546 1.1 dbSUPER 0.7 +1.6 1637 1.0 PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 FEZF1 YY1 ZNF766 CBX5 ERI3 RNU6-369P RNF220 DMAP1 MIR5584 PIR47647
GH01G044549 0.9 dbSUPER 0.7 +4.4 4412 1.5 HDGF HDAC1 ATF1 CBX3 CREB3L1 RB1 ARNT ARID4B ZNF2 RAD21 ERI3 RNU6-369P RNF220 B4GALT2 ATP6V0B MIR5584 PIR47647
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5584 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5584 Gene

Chromosome:
1
Start:
44,545,493 bp from pter
End:
44,545,552 bp from pter
Size:
60 bases
Orientation:
Plus strand

Genomic View for MIR5584 Gene

Genes around MIR5584 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5584 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5584 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5584 Gene

Proteins for MIR5584 Gene

Post-translational modifications for MIR5584 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5584 Gene

Domains & Families for MIR5584 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5584 Gene

Function for MIR5584 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5584 Gene

Localization for MIR5584 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5584 Gene

Pathways & Interactions for MIR5584 Gene

SuperPathways for MIR5584 Gene

No Data Available

Interacting Proteins for MIR5584 Gene

Gene Ontology (GO) - Biological Process for MIR5584 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5584 Gene

Drugs & Compounds for MIR5584 Gene

No Compound Related Data Available

Transcripts for MIR5584 Gene

mRNA/cDNA for MIR5584 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5584 Gene

No ASD Table

Relevant External Links for MIR5584 Gene

GeneLoc Exon Structure for
MIR5584
ECgene alternative splicing isoforms for
MIR5584

Expression for MIR5584 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5584 Gene:

MIR5584
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5584 Gene

Orthologs for MIR5584 Gene

Evolution for MIR5584 Gene

ENSEMBL:
Gene Tree for MIR5584 (if available)
TreeFam:
Gene Tree for MIR5584 (if available)

No data available for Orthologs for MIR5584 Gene

Paralogs for MIR5584 Gene

No data available for Paralogs for MIR5584 Gene

Variants for MIR5584 Gene

Sequence variations from dbSNP and Humsavar for MIR5584 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001276746 -- 44,544,601(+) ATAGA(A/G)CTGTC intron-variant, upstream-variant-2KB
rs1005047253 -- 44,545,614(+) GGGTG(A/G)GGGTG intron-variant, downstream-variant-500B
rs1005137030 -- 44,544,646(+) CCTTT(C/T)TGGAA intron-variant, upstream-variant-2KB
rs1006402942 -- 44,545,914(+) ACCAC(A/G)CCCGG intron-variant, downstream-variant-500B
rs1006859284 -- 44,545,183(+) CCTCA(C/G/T)AGAAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5584 Gene

Variant ID Type Subtype PubMed ID
nsv461395 CNV gain 19166990
nsv546144 CNV gain 21841781
nsv744 CNV insertion 18451855

Relevant External Links for MIR5584 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5584

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5584 Gene

Disorders for MIR5584 Gene

Relevant External Links for MIR5584

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5584

No disorders were found for MIR5584 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5584 Gene

Publications for MIR5584 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5584 Gene

Sources for MIR5584 Gene

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