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Aliases for MIR5581 Gene

Subcategory (RNA class) for MIR5581 Gene


Quality Score for this RNA gene is


Aliases for MIR5581 Gene

  • MicroRNA 5581 2 3 5
  • Hsa-Mir-5581 3

External Ids for MIR5581 Gene

Previous GeneCards Identifiers for MIR5581 Gene

  • GC01U903354
  • GC01M037969

Summaries for MIR5581 Gene

Entrez Gene Summary for MIR5581 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5581 Gene

MIR5581 (MicroRNA 5581) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5581 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5581 Gene

Genomics for MIR5581 Gene

Regulatory Elements for MIR5581 Gene

Enhancers for MIR5581 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H037498 1.1 Ensembl ENCODE dbSUPER 0.7 +1.6 1626 1 ZNF121 NFIC JUND ZBTB48 ZNF600 NR3C1 RFX5 GNL2 DNALI1 MEAF6 C1orf109 CDCA8 EPHA10 LINC01137 MIR5581 PIR46555
GH01H037497 0.8 ENCODE dbSUPER 0.7 +3.0 2952 0 NFIB NFIA YY2 ZNF10 ZNF600 ZFX YY1 LINC01137 ZC3H12A SNIP1 DNALI1 RPS27P9 MIR5581 PIR46555
GH01H037513 1.1 ENCODE 0.4 -13.6 -13638 2 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 ZNF143 SF3A3 GNL2 DNALI1 FTH1P1 MEAF6 SNIP1 RPS27P9 YRDC C1orf109 LINC01137
GH01H037507 0.8 ENCODE dbSUPER 0.4 -7.1 -7126 0 EED IKZF1 JUNB BATF IKZF2 DNALI1 LINC01137 ZC3H12A SNIP1 RPS27P9 GNL2 MEAF6 MIR5581
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5581 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5581 Gene

37,500,935 bp from pter
37,500,994 bp from pter
60 bases
Minus strand

Genomic View for MIR5581 Gene

Genes around MIR5581 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5581 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5581 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5581 Gene

ORGUL Member Location for MIR5581 Gene

ORGUL Member Location for MIR5581 gene

Proteins for MIR5581 Gene

Post-translational modifications for MIR5581 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5581 Gene

Domains & Families for MIR5581 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5581 Gene

Function for MIR5581 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5581
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5581 Gene

Localization for MIR5581 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5581 Gene

Pathways & Interactions for MIR5581 Gene

SuperPathways for MIR5581 Gene

No Data Available

Interacting Proteins for MIR5581 Gene

Gene Ontology (GO) - Biological Process for MIR5581 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5581 Gene

Drugs & Compounds for MIR5581 Gene

No Compound Related Data Available

Transcripts for MIR5581 Gene

mRNA/cDNA for MIR5581 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5581
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5581 Gene

No ASD Table

Relevant External Links for MIR5581 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5581 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5581 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5581 Gene

Orthologs for MIR5581 Gene

Evolution for MIR5581 Gene

Gene Tree for MIR5581 (if available)
Gene Tree for MIR5581 (if available)

No data available for Orthologs for MIR5581 Gene

Paralogs for MIR5581 Gene

No data available for Paralogs for MIR5581 Gene

Variants for MIR5581 Gene

Sequence variations from dbSNP and Humsavar for MIR5581 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000980879 -- 37,501,337(+) AACTT(A/G)TATTT intron-variant, upstream-variant-2KB
rs1001118570 -- 37,502,490(+) AGGGG(C/G)GGCCA intron-variant, upstream-variant-2KB
rs1002216716 -- 37,501,605(+) TGTCC(C/T)GGAGT intron-variant, upstream-variant-2KB
rs1005760209 -- 37,502,447(+) ACAGT(A/G)ATGTA intron-variant, upstream-variant-2KB
rs1005993234 -- 37,502,901(+) AGGCA(C/T)GAGCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5581 Gene

Variant ID Type Subtype PubMed ID
nsv519551 CNV gain 19592680
nsv524834 CNV gain 19592680

Relevant External Links for MIR5581 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5581 Gene

Disorders for MIR5581 Gene

Relevant External Links for MIR5581

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5581 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5581 Gene

Publications for MIR5581 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR5581 Gene

Sources for MIR5581 Gene

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