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Aliases for MIR5581 Gene

Subcategory (RNA class) for MIR5581 Gene


Quality Score for this RNA gene is


Aliases for MIR5581 Gene

  • MicroRNA 5581 2 3 5
  • Hsa-Mir-5581 3

External Ids for MIR5581 Gene

Previous GeneCards Identifiers for MIR5581 Gene

  • GC01U903354
  • GC01M037969

Summaries for MIR5581 Gene

Entrez Gene Summary for MIR5581 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5581 Gene

MIR5581 (MicroRNA 5581) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5581 Gene

Genomics for MIR5581 Gene

Regulatory Elements for MIR5581 Gene

Enhancers for MIR5581 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F037497 0.2 ENCODE 0.8 +3.0 2952 0.1 NFIA YY2 ZNF600 YY1 ZC3H12A LINC01137 MIR6732 RPS27P9 SNIP1 DNALI1 MIR5581 PIR46555
GH01F037498 0.2 ENCODE 0.8 +1.6 1626 1.3 ZNF121 JUND ZBTB48 ZNF600 NR3C1 RFX5 GNL2 DNALI1 MEAF6 C1orf109 CDCA8 EPHA10 LINC01137 MIR5581 PIR46555
GH01F037507 0.2 ENCODE 0.4 -7.1 -7126 0.9 BCOR ZNF146 IKZF1 EED ZNF580 JUNB KDM1A DNALI1 LINC01137 MIR6732 ZC3H12A RPS27P9 SNIP1 GNL2 MEAF6 MIR5581
GH01F037513 0.2 ENCODE 0.4 -13.6 -13638 2.6 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 ZNF143 SNIP1 GNL2 DNALI1 MEAF6 SF3A3 RPS27P9 FTH1P1 RSPO1 LINC01137 MIR5581
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR5581 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5581 Gene

37,500,935 bp from pter
37,500,994 bp from pter
60 bases
Minus strand

Genomic View for MIR5581 Gene

Genes around MIR5581 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5581 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5581 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5581 Gene

ORGUL Member Location for MIR5581 Gene

ORGUL Member Location for MIR5581 gene

Proteins for MIR5581 Gene

Post-translational modifications for MIR5581 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5581 Gene

Domains & Families for MIR5581 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5581 Gene

Function for MIR5581 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5581 Gene

Localization for MIR5581 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5581 Gene

Pathways & Interactions for MIR5581 Gene

SuperPathways for MIR5581 Gene

No Data Available

Interacting Proteins for MIR5581 Gene

Gene Ontology (GO) - Biological Process for MIR5581 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5581 Gene

Transcripts for MIR5581 Gene

mRNA/cDNA for MIR5581 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5581 Gene

No ASD Table

Relevant External Links for MIR5581 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5581 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5581 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5581 Gene

Orthologs for MIR5581 Gene

Evolution for MIR5581 Gene

Gene Tree for MIR5581 (if available)
Gene Tree for MIR5581 (if available)

No data available for Orthologs for MIR5581 Gene

Paralogs for MIR5581 Gene

No data available for Paralogs for MIR5581 Gene

Variants for MIR5581 Gene

Sequence variations from dbSNP and Humsavar for MIR5581 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs112642575 -- 37,502,477(+) TGTAC(-/A)AAAAA intron-variant, upstream-variant-2KB
rs114352576 -- 37,502,951(+) ATTTC(A/G)AGACA intron-variant, upstream-variant-2KB
rs115342111 -- 37,502,380(+) CTATA(A/G)TCTTA intron-variant, upstream-variant-2KB
rs139087392 -- 37,500,500(+) AATTT(G/T)TGCTA intron-variant, downstream-variant-500B
rs140191437 -- 37,501,131(+) ACCCT(C/T)TCTGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5581 Gene

Variant ID Type Subtype PubMed ID
nsv519551 CNV gain 19592680
nsv524834 CNV gain 19592680

Relevant External Links for MIR5581 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5581 Gene

Disorders for MIR5581 Gene

Relevant External Links for MIR5581

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5581 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5581 Gene

Publications for MIR5581 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5581 Gene

Sources for MIR5581 Gene

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