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Aliases for MIR5580 Gene

Subcategory (RNA class) for MIR5580 Gene


Quality Score for this RNA gene is


Aliases for MIR5580 Gene

  • MicroRNA 5580 2 3 5
  • Hsa-Mir-5580 3

External Ids for MIR5580 Gene

Previous GeneCards Identifiers for MIR5580 Gene

  • GC14U901303
  • GC14M054419

Summaries for MIR5580 Gene

Entrez Gene Summary for MIR5580 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5580 Gene

MIR5580 (MicroRNA 5580) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5580 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5580 Gene

Genomics for MIR5580 Gene

GeneHancer (GH) Regulatory Elements for MIR5580 Gene

Promoters and enhancers for MIR5580 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I053946 Enhancer 1.1 Ensembl ENCODE dbSUPER 550.8 +1.6 1585 1.7 SOX13 CTCF ESRRA FOXA2 SIN3A RARA ETS1 E2F1 EZH2 SMARCE1 MIR5580 BMP4 ENSG00000231922
GH14I053950 Promoter/Enhancer 2.4 VISTA EPDnew Ensembl ENCODE dbSUPER 0.4 -6.0 -6009 7.8 ARID4B SIN3A FEZF1 ZBTB7B ZNF48 ETS1 ZNF121 ELK1 PAF1 SP3 BMP4 MIR5580
GH14I053942 Enhancer 1 Ensembl ENCODE 0.4 +5.0 5043 1.6 FOXA2 MLX ARID4B SIN3A RAD21 THRB RARA CREM THAP11 MIXL1 BMP4 MIR5580 ENSG00000231922
GH14I053924 Enhancer 0.8 ENCODE dbSUPER 0.3 +23.5 23466 1.3 FOXA2 JUN USF2 MAX CEBPB FOXA1 GATA3 FOS FOSL2 MAFK ENSG00000231922 MIR5580
GH14I053927 Enhancer 0.6 ENCODE 0.3 +21.0 21039 0.9 SOX5 SOX13 FOXA2 TEAD1 FOXA3 JUN TEAD3 SP1 CEBPA FOSL2 BMP4 ENSG00000231922 MIR5580
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5580 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5580 Gene

Genomic Locations for MIR5580 Gene
58 bases
Minus strand

Genomic View for MIR5580 Gene

Genes around MIR5580 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5580 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5580 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5580 Gene

ORGUL Member Location for MIR5580 Gene

ORGUL Member Location for MIR5580 gene

Proteins for MIR5580 Gene

Post-translational modifications for MIR5580 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5580 Gene

Domains & Families for MIR5580 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5580 Gene

Function for MIR5580 Gene

Phenotypes From GWAS Catalog for MIR5580 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5580 Gene

Localization for MIR5580 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5580 Gene

Pathways & Interactions for MIR5580 Gene

SuperPathways for MIR5580 Gene

No Data Available

Interacting Proteins for MIR5580 Gene

Gene Ontology (GO) - Biological Process for MIR5580 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5580 Gene

Drugs & Compounds for MIR5580 Gene

No Compound Related Data Available

Transcripts for MIR5580 Gene

mRNA/cDNA for MIR5580 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5580 Gene

No ASD Table

Relevant External Links for MIR5580 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5580 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5580 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5580 Gene

Orthologs for MIR5580 Gene

Evolution for MIR5580 Gene

Gene Tree for MIR5580 (if available)
Gene Tree for MIR5580 (if available)

No data available for Orthologs for MIR5580 Gene

Paralogs for MIR5580 Gene

No data available for Paralogs for MIR5580 Gene

Variants for MIR5580 Gene

Sequence variations from dbSNP and Humsavar for MIR5580 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs121912766 pathogenic, Orofacial cleft 11 53,950,222(-) G/A upstream_transcript_variant
rs121912768 pathogenic, Orofacial cleft 11 53,950,399(-) C/A/T upstream_transcript_variant
rs140085940 uncertain-significance, Syndromic Microphthalmia, Dominant, Orofacial cleft, Cleft Lip +/- Cleft Palate, Autosomal Dominant, BMP4-Related Syndromic Microphthalmia 53,949,883(-) CT/ upstream_transcript_variant
rs568281464 uncertain-significance, Orofacial cleft, Syndromic Microphthalmia, Dominant, BMP4-Related Syndromic Microphthalmia, Cleft Lip +/- Cleft Palate, Autosomal Dominant 53,949,760(-) T/C upstream_transcript_variant
rs573118445 uncertain-significance, Cleft Lip +/- Cleft Palate, Autosomal Dominant, Syndromic Microphthalmia, Dominant, BMP4-Related Syndromic Microphthalmia, Orofacial cleft 53,949,781(-) G/A upstream_transcript_variant

Additional Variant Information for MIR5580 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5580 Gene

Disorders for MIR5580 Gene

Additional Disease Information for MIR5580

No disorders were found for MIR5580 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5580 Gene

Publications for MIR5580 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5580 Gene

Sources for MIR5580 Gene

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