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Aliases for MIR5579 Gene

Subcategory (RNA class) for MIR5579 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5579 Gene

  • MicroRNA 5579 2 3 5
  • Hsa-Mir-5579 3

External Ids for MIR5579 Gene

Previous GeneCards Identifiers for MIR5579 Gene

  • GC11U901906
  • GC11M079136

Summaries for MIR5579 Gene

Entrez Gene Summary for MIR5579 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5579 Gene

MIR5579 (MicroRNA 5579) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5579 Gene

Genomics for MIR5579 Gene

Regulatory Elements for MIR5579 Gene

Enhancers for MIR5579 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G079417 1.2 FANTOM5 ENCODE dbSUPER 0.7 +3.4 3445 2.5 NFIB JUN BHLHE40 ZNF133 MNT DPF2 ATF2 CTBP1 NFIC JUND TENM4 MIR5579 MIR708
GH11G079436 1.6 FANTOM5 ENCODE dbSUPER 0.4 -17.3 -17307 5.4 SIN3A ZNF2 GLIS2 FOS SP3 MAFF CBX8 SMARCA4 ZSCAN16 GLIS1 TENM4 MIR5579
GH11G079412 1.1 Ensembl ENCODE dbSUPER 0.4 +7.7 7709 3.4 ZNF146 BHLHE40 EBF1 RAD21 JUND ZNF302 SMARCA4 ZSCAN5C SCRT2 KDM1A TENM4 MIR5579 MIR708
GH11G079406 1 FANTOM5 ENCODE 0.4 +15.7 15677 0.3 BACH1 BMI1 RELA GATA3 CTBP1 EED RCOR1 RELB IKZF2 ZNF687 MIR708 MIR5579
GH11G079421 0.4 ENCODE 0.7 -0.3 -342 1.4 GLIS1 ZIC2 TENM4 MIR5579
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5579 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5579 Gene

Chromosome:
11
Start:
79,422,169 bp from pter
End:
79,422,226 bp from pter
Size:
58 bases
Orientation:
Minus strand

Genomic View for MIR5579 Gene

Genes around MIR5579 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5579 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5579 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5579 Gene

ORGUL Member Location for MIR5579 Gene

ORGUL Member Location for MIR5579 gene

Proteins for MIR5579 Gene

Post-translational modifications for MIR5579 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5579 Gene

Domains & Families for MIR5579 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5579 Gene

Function for MIR5579 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5579 Gene

Localization for MIR5579 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5579 Gene

Pathways & Interactions for MIR5579 Gene

SuperPathways for MIR5579 Gene

No Data Available

Interacting Proteins for MIR5579 Gene

Gene Ontology (GO) - Biological Process for MIR5579 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5579 Gene

Drugs & Compounds for MIR5579 Gene

No Compound Related Data Available

Transcripts for MIR5579 Gene

mRNA/cDNA for MIR5579 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5579 Gene

No ASD Table

Relevant External Links for MIR5579 Gene

GeneLoc Exon Structure for
MIR5579
ECgene alternative splicing isoforms for
MIR5579

Expression for MIR5579 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5579 Gene:

MIR5579
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5579 Gene

Orthologs for MIR5579 Gene

Evolution for MIR5579 Gene

ENSEMBL:
Gene Tree for MIR5579 (if available)
TreeFam:
Gene Tree for MIR5579 (if available)

No data available for Orthologs for MIR5579 Gene

Paralogs for MIR5579 Gene

No data available for Paralogs for MIR5579 Gene

Variants for MIR5579 Gene

Sequence variations from dbSNP and Humsavar for MIR5579 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000255313 -- 79,421,992(+) GCACA(C/T)CCCAC intron-variant, downstream-variant-500B
rs1001592832 -- 79,424,086(+) TAGTT(C/T)GTCTG intron-variant, upstream-variant-2KB
rs1002319138 -- 79,424,204(+) CACAA(C/T)TGGCG intron-variant, upstream-variant-2KB
rs1005416906 -- 79,423,800(+) GGAGG(C/T)CTGCA intron-variant, upstream-variant-2KB
rs1006766682 -- 79,422,238(+) CACCC(A/T)CATGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5579 Gene

Variant ID Type Subtype PubMed ID
nsv832216 CNV gain 17160897

Relevant External Links for MIR5579 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5579

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5579 Gene

Disorders for MIR5579 Gene

Relevant External Links for MIR5579

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5579

No disorders were found for MIR5579 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5579 Gene

Publications for MIR5579 Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5579 Gene

Sources for MIR5579 Gene

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