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Aliases for MIR5572 Gene

Subcategory (RNA class) for MIR5572 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5572 Gene

  • MicroRNA 5572 2 3 5
  • Hsa-Mir-5572 3

External Ids for MIR5572 Gene

Previous GeneCards Identifiers for MIR5572 Gene

  • GC15U901439
  • GC15P080876
  • GC15P080405

Summaries for MIR5572 Gene

Entrez Gene Summary for MIR5572 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5572 Gene

MIR5572 (MicroRNA 5572) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR5572 include Webb-Dattani Syndrome. Among its related pathways are Cytochrome P450 - arranged by substrate type and Circadian rythm related genes.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5572 Gene

Genomics for MIR5572 Gene

Regulatory Elements for MIR5572 Gene

Enhancers for MIR5572 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G080578 1.3 FANTOM5 ENCODE dbSUPER 0.7 -0.1 -54 4.4 PKNOX1 MXI1 JUN MAX GTF3C2 FOS NR2F6 TCF7L2 STAT1 ZNF280D ENSG00000259649 CEMIP RNU6-380P ENSG00000270919 MIR5572
GH15G080583 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +6.4 6411 7.8 PKNOX1 FOXA2 NFIB ZSCAN4 BRCA1 RAD21 YY1 GATA2 RCOR1 FOS CEMIP TLNRD1 ARNT2 MIR5572 GC15P080662
GH15G080595 0.9 ENCODE dbSUPER 0.4 +15.6 15567 1.9 SOX13 GATAD2A SAP130 FOXA3 HMG20A NR3C1 RARA TEAD3 NFIC JUND ARNT2 MIR5572 GC15P080662
GH15G080614 1.2 ENCODE dbSUPER 0.3 +34.9 34948 2.7 HDGF ZNF133 ZNF48 ZBTB7B ZNF207 ZNF662 ZNF592 ZFP41 PBX2 MYNN RNU6-380P CEMIP MIR5572 GC15P080662
GH15G080599 0.8 ENCODE dbSUPER 0.4 +18.5 18528 1.2 SMARCA4 GATA2 JUN CREB1 FOS MAFK ARNT2 MIR5572 GC15P080662
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5572 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5572 Gene

Chromosome:
15
Start:
80,581,103 bp from pter
End:
80,581,239 bp from pter
Size:
137 bases
Orientation:
Plus strand

Genomic View for MIR5572 Gene

Genes around MIR5572 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5572 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5572 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5572 Gene

Proteins for MIR5572 Gene

Post-translational modifications for MIR5572 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5572 Gene

Domains & Families for MIR5572 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5572 Gene

Function for MIR5572 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5572 Gene

Localization for MIR5572 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5572 Gene

Drugs & Compounds for MIR5572 Gene

No Compound Related Data Available

Transcripts for MIR5572 Gene

mRNA/cDNA for MIR5572 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5572 Gene

No ASD Table

Relevant External Links for MIR5572 Gene

GeneLoc Exon Structure for
MIR5572
ECgene alternative splicing isoforms for
MIR5572

Expression for MIR5572 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5572 Gene

mRNA differential expression in normal tissues according to GTEx for MIR5572 Gene

This gene is overexpressed in Testis (x14.7), Brain - Nucleus accumbens (basal ganglia) (x5.0), and Liver (x4.4).

NURSA nuclear receptor signaling pathways regulating expression of MIR5572 Gene:

MIR5572
genes like me logo Genes that share expression patterns with MIR5572: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5572 Gene

Orthologs for MIR5572 Gene

Evolution for MIR5572 Gene

ENSEMBL:
Gene Tree for MIR5572 (if available)
TreeFam:
Gene Tree for MIR5572 (if available)

No data available for Orthologs for MIR5572 Gene

Paralogs for MIR5572 Gene

No data available for Paralogs for MIR5572 Gene

Variants for MIR5572 Gene

Sequence variations from dbSNP and Humsavar for MIR5572 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000563513 -- 80,581,327(+) CTACA(A/G)CCCCC downstream-variant-500B, reference, missense
rs1003785761 -- 80,580,328(+) CCCAG(A/G)GCAGA intron-variant, upstream-variant-2KB
rs1003997676 -- 80,579,429(+) AAAGG(A/G)ATCAG intron-variant, upstream-variant-2KB
rs1004286733 -- 80,579,345(+) GTCCC(C/T)TTTAT intron-variant, upstream-variant-2KB
rs1004526208 -- 80,580,357(+) ACGTA(A/G)ACTCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5572 Gene

Variant ID Type Subtype PubMed ID
nsv471685 CNV gain 15918152
nsv570235 CNV loss 21841781

Relevant External Links for MIR5572 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5572

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5572 Gene

Disorders for MIR5572 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR5572 Gene - From: GeneCards

Disorder Aliases PubMed IDs
webb-dattani syndrome
  • hypothalamo-pituitary-frontotemporal hypoplasia with visual and renal anomalies
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR5572

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5572
genes like me logo Genes that share disorders with MIR5572: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR5572 Gene

Publications for MIR5572 Gene

  1. Deep sequencing of short RNAs reveals novel microRNAs in minor salivary glands of patients with SjAPgren's syndrome. (PMID: 21895886) Tandon M. … Alevizos I. (Oral Dis 2012) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5572 Gene

Sources for MIR5572 Gene

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