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Aliases for MIR554 Gene

Subcategory (RNA class) for MIR554 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR554 Gene

  • MicroRNA 554 2 3 5
  • Hsa-Mir-554 3
  • MIRN554 3

External Ids for MIR554 Gene

ORGUL Members for MIR554 Gene

Previous HGNC Symbols for MIR554 Gene

  • MIRN554

Previous GeneCards Identifiers for MIR554 Gene

  • GC01P149785
  • GC01P151519

Summaries for MIR554 Gene

Entrez Gene Summary for MIR554 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR554 Gene

MIR554 (MicroRNA 554) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR554 Gene

Genomics for MIR554 Gene

Regulatory Elements for MIR554 Gene

Enhancers for MIR554 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G151494 1.5 Ensembl ENCODE dbSUPER 10.9 -50.7 -50667 1.5 PKNOX1 SIN3A FEZF1 ZNF2 FOS SP3 JUNB TSHZ1 TBX21 ZNF518A ENSG00000252840 POGZ TUFT1 MIR554 RPS10P6 ENSG00000232536 ENSG00000227045 RIIAD1 CELF3 SNX27
GH01G151606 1.5 FANTOM5 Ensembl ENCODE 10.8 +61.2 61208 1.9 PKNOX1 NFIB SIN3A RFX5 ZNF121 GATA2 ZNF366 SCRT2 FOS SMARCC1 TUFT1 RPS10P6 MIR554 ENSG00000252840 ENSG00000227045 CGN RIIAD1 CELF3 ENSG00000232536 MRPL9
GH01G151610 1.4 ENCODE dbSUPER 10.8 +66.3 66303 3.5 HDGF PKNOX1 FOXA2 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 SETDB1 CTSK UBE2D3P3 GOLPH3L GABPB2 RPS10P6 MIR554 TUFT1 ENSG00000252840 ENSG00000227045
GH01G151818 1.4 FANTOM5 ENCODE dbSUPER 10.4 +274.3 274333 2.7 NFIB YY1 ZNF335 ZNF121 GLIS2 ELK1 SCRT2 CEBPB ZHX2 REST TDRKH TDRKH-AS1 ENSG00000201134 C2CD4D THEM5 ENSG00000232937 MRPL9 OAZ3 RPS10P6 TUFT1
GH01G151580 1.2 Ensembl ENCODE 11.8 +38.3 38251 6.1 HDGF PKNOX1 NFIB SIN3A BMI1 RAD21 GATA2 HSF1 SCRT2 ZNF207 RPS10P6 MIR554 TUFT1 ENSG00000232536 SNX27 RIIAD1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR554 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR554 Gene

Chromosome:
1
Start:
151,545,796 bp from pter
End:
151,545,891 bp from pter
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR554 Gene

Genes around MIR554 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR554 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR554 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR554 Gene

Proteins for MIR554 Gene

Post-translational modifications for MIR554 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR554 Gene

Domains & Families for MIR554 Gene

Gene Families for MIR554 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR554: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR554 Gene

Function for MIR554 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR554 Gene

Localization for MIR554 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR554 Gene

Pathways & Interactions for MIR554 Gene

SuperPathways for MIR554 Gene

No Data Available

Interacting Proteins for MIR554 Gene

Gene Ontology (GO) - Biological Process for MIR554 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR554 Gene

Drugs & Compounds for MIR554 Gene

No Compound Related Data Available

Transcripts for MIR554 Gene

mRNA/cDNA for MIR554 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR554 Gene

No ASD Table

Relevant External Links for MIR554 Gene

GeneLoc Exon Structure for
MIR554
ECgene alternative splicing isoforms for
MIR554

Expression for MIR554 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR554 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR554 Gene:

MIR554
genes like me logo Genes that share expression patterns with MIR554: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR554 Gene

Orthologs for MIR554 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR554 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-554 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR554 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR554 Gene

ENSEMBL:
Gene Tree for MIR554 (if available)
TreeFam:
Gene Tree for MIR554 (if available)

Paralogs for MIR554 Gene

No data available for Paralogs for MIR554 Gene

Variants for MIR554 Gene

Sequence variations from dbSNP and Humsavar for MIR554 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000164713 -- 151,545,059(+) TAATC(C/T)CAGCA intron-variant, upstream-variant-2KB
rs1000642829 -- 151,545,266(+) GATCA(C/T)GCCAT intron-variant, upstream-variant-2KB
rs1002145374 -- 151,545,734(+) CAGGT(C/G)CCTCA intron-variant, upstream-variant-2KB
rs1003149327 -- 151,545,885(+) CTCTG(C/G)GCATC intron-variant, nc-transcript-variant
rs1003180351 -- 151,545,560(+) TAGCT(A/G)TTATT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR554 Gene

Variant ID Type Subtype PubMed ID
nsv997511 CNV gain 25217958

Relevant External Links for MIR554 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR554

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR554 Gene

Disorders for MIR554 Gene

Relevant External Links for MIR554

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR554

No disorders were found for MIR554 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR554 Gene

Publications for MIR554 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 64

Products for MIR554 Gene

Sources for MIR554 Gene

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