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Aliases for MIR552 Gene

Subcategory (RNA class) for MIR552 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR552 Gene

  • MicroRNA 552 2 3
  • Hsa-Mir-552 3
  • MIRN552 3

External Ids for MIR552 Gene

Previous Symbols for MIR552 Gene

  • MIRN552

Summaries for MIR552 Gene

Entrez Gene Summary for MIR552 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR552 Gene

MIR552 (MicroRNA 552) is a RNA Gene, and belongs to miRNA RNA class.

fRNAdb sequence ontologies for MIR552 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR552

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR552 Gene

Genomics for MIR552 Gene

Genomic Location for MIR552 Gene

Start:
34,669,599 bp from pter
End:
34,669,694 bp from pter
Size:
96 bases
Orientation:
Minus strand

Genomic View for MIR552 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR552 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR552 Gene

ORGUL Member Location for MIR552 Gene

ORGUL Member Location for MIR552 gene

No data available for Regulatory Elements for MIR552 Gene

Proteins for MIR552 Gene

Post-translational modifications for MIR552 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR552 Gene

Domains for MIR552 Gene

Gene Families for MIR552 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR552: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR552 Gene

Function for MIR552 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR552 Gene

Localization for MIR552 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR552 Gene

Pathways for MIR552 Gene

SuperPathways for MIR552 Gene

No Data Available

Interacting Proteins for MIR552 Gene

Gene Ontology (GO) - Biological Process for MIR552 Gene

None

No data available for Pathways by source for MIR552 Gene

Transcripts for MIR552 Gene

fRNAdb Secondary structures for MIR552 Gene

  • hsa-mir-552_MI0003557_Homo_sapiens_miR-552_stem-loop_hairpin

mRNA/cDNA for MIR552 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR552 Gene

No ASD Table

Relevant External Links for MIR552 Gene

GeneLoc Exon Structure for
MIR552
ECgene alternative splicing isoforms for
MIR552

Expression for MIR552 Gene

mRNA expression in normal human tissues for MIR552 Gene

genes like me logo Genes that share expressions with MIR552: view

Orthologs for MIR552 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR552 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-552 37
  • 100 (a)
OneToOne
Species with no ortholog for MIR552:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR552 Gene

ENSEMBL:
Gene Tree for MIR552 (if available)
TreeFam:
Gene Tree for MIR552 (if available)

Paralogs for MIR552 Gene

No data available for Paralogs for MIR552 Gene

Variants for MIR552 Gene

Sequence variations from dbSNP and Humsavar for MIR552 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs600152 -- 34,671,378(-) agagg(C/T)caggc upstream-variant-2KB
rs2147383 -- 34,671,354(-) ACTCT(A/C)GAGCC upstream-variant-2KB
rs2147385 -- 34,669,714(-) tagtc(A/G)aaTAT upstream-variant-2KB
rs2181898 -- 34,671,610(-) CCCAG(C/G)CTGCT upstream-variant-2KB
rs4653077 -- 34,670,604(+) cttga(A/T)cttat upstream-variant-2KB

Relevant External Links for MIR552 Gene

HapMap Linkage Disequilibrium report
MIR552

No data available for Structural Variations from Database of Genomic Variants (DGV) for MIR552 Gene

Disorders for MIR552 Gene

No disorders were found for MIR552 Gene.

No data available for UniProtKB/Swiss-Prot for MIR552 Gene

Publications for MIR552 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3
  4. miR-592 and miR-552 can distinguish between primary lung adenocarcinoma and colorectal cancer metastases in the lung. (PMID: 24778034) Kim J. … Lee G.K. (Anticancer Res. 2014) 3
  5. MiR-5000-3p, miR-5009-3P and miR-552: potential microRNA biomarkers of side population cells in colon cancer. (PMID: 24898979) Xia Z.S. … Chen G.C. (Oncol. Rep. 2014) 3

Products for MIR552 Gene

Sources for MIR552 Gene

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