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Aliases for MIR550B2 Gene

Subcategory (RNA class) for MIR550B2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR550B2 Gene

  • MicroRNA 550b-2 2 3
  • Hsa-Mir-550a-2 5
  • Hsa-Mir-550b-2 3

External Ids for MIR550B2 Gene

Previous GeneCards Identifiers for MIR550B2 Gene

  • GC07U903079

Summaries for MIR550B2 Gene

Entrez Gene Summary for MIR550B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR550B2 Gene

MIR550B2 (MicroRNA 550b-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR550B2 Gene

Genomics for MIR550B2 Gene

Genomic Location for MIR550B2 Gene

Chromosome:
7
Start:
32,732,981 bp from pter
End:
32,733,077 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR550B2 Gene

Genes around MIR550B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR550B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR550B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR550B2 Gene

ORGUL Member Location for MIR550B2 Gene

ORGUL Member Location for MIR550B2 gene

No data available for Regulatory Elements for MIR550B2 Gene

Proteins for MIR550B2 Gene

Post-translational modifications for MIR550B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR550B2 Gene

Domains & Families for MIR550B2 Gene

Gene Families for MIR550B2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR550B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR550B2 Gene

Function for MIR550B2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR550B2 Gene

Localization for MIR550B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR550B2 Gene

Pathways & Interactions for MIR550B2 Gene

SuperPathways for MIR550B2 Gene

No Data Available

Interacting Proteins for MIR550B2 Gene

Gene Ontology (GO) - Biological Process for MIR550B2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR550B2 Gene

Transcripts for MIR550B2 Gene

mRNA/cDNA for MIR550B2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR550B2 Gene

No ASD Table

Relevant External Links for MIR550B2 Gene

GeneLoc Exon Structure for
MIR550B2
ECgene alternative splicing isoforms for
MIR550B2

Expression for MIR550B2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR550B2 Gene:

MIR550B2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR550B2 Gene

Orthologs for MIR550B2 Gene

Evolution for MIR550B2 Gene

ENSEMBL:
Gene Tree for MIR550B2 (if available)
TreeFam:
Gene Tree for MIR550B2 (if available)

No data available for Orthologs for MIR550B2 Gene

Paralogs for MIR550B2 Gene

No data available for Paralogs for MIR550B2 Gene

Variants for MIR550B2 Gene

Sequence variations from dbSNP and Humsavar for MIR550B2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1003777080 -- 32,734,395(+) CTTGG(A/G)TTTTG upstream-variant-2KB
rs1005778013 -- 32,734,205(+) GATAT(A/G)TGTGA upstream-variant-2KB
rs1006526079 -- 32,732,712(+) AGGAA(C/T)GTTTG downstream-variant-500B, upstream-variant-2KB
rs1007007194 -- 32,733,585(+) CTATG(A/G)GTCAA upstream-variant-2KB
rs1007101868 -- 32,733,234(+) ACTAA(C/G)TATTA downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR550B2 Gene

Variant ID Type Subtype PubMed ID
dgv1080e201 CNV deletion 23290073
esv29452 CNV gain+loss 19812545
esv3612745 CNV gain 21293372
nsv1068321 OTHER inversion 25765185
nsv1148830 OTHER inversion 26484159
nsv436907 CNV insertion 17901297
nsv830941 CNV gain 17160897
nsv966773 CNV duplication 23825009

Relevant External Links for MIR550B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR550B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR550B2 Gene

Disorders for MIR550B2 Gene

Relevant External Links for MIR550B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR550B2

No disorders were found for MIR550B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR550B2 Gene

Publications for MIR550B2 Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR550B2 Gene

Sources for MIR550B2 Gene

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