Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR550B2 Gene

Subcategory (RNA class) for MIR550B2 Gene

miRNA

Quality Score for this RNA gene is

7

Aliases for MIR550B2 Gene

  • MicroRNA 550b-2 2 3
  • Hsa-Mir-550b-2 3

External Ids for MIR550B2 Gene

Previous GeneCards Identifiers for MIR550B2 Gene

  • GC07U903079

Summaries for MIR550B2 Gene

Entrez Gene Summary for MIR550B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR550B2 Gene

MIR550B2 (MicroRNA 550b-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR550B2 Gene

Genomics for MIR550B2 Gene

Genomic Location for MIR550B2 Gene

Start:
32,732,981 bp from pter
End:
32,733,077 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR550B2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR550B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR550B2 Gene

ORGUL Member Location for MIR550B2 Gene

ORGUL Member Location for MIR550B2 gene

No data available for Regulatory Elements for MIR550B2 Gene

Proteins for MIR550B2 Gene

Post-translational modifications for MIR550B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR550B2 Gene

Domains for MIR550B2 Gene

Gene Families for MIR550B2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR550B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR550B2 Gene

Function for MIR550B2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR550B2 Gene

Localization for MIR550B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR550B2 Gene

Pathways for MIR550B2 Gene

SuperPathways for MIR550B2 Gene

No Data Available

Interacting Proteins for MIR550B2 Gene

Gene Ontology (GO) - Biological Process for MIR550B2 Gene

None

No data available for Pathways by source for MIR550B2 Gene

Transcripts for MIR550B2 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR550B2 Gene

No ASD Table

Relevant External Links for MIR550B2 Gene

GeneLoc Exon Structure for
MIR550B2
ECgene alternative splicing isoforms for
MIR550B2

No data available for mRNA/cDNA for MIR550B2 Gene

Expression for MIR550B2 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR550B2 Gene

Orthologs for MIR550B2 Gene

No data available for Orthologs and Evolution for MIR550B2 Gene

Paralogs for MIR550B2 Gene

No data available for Paralogs for MIR550B2 Gene

Variants for MIR550B2 Gene

Sequence variations from dbSNP and Humsavar for MIR550B2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2443128 -- 32,733,740(+) ctgtt(A/T)ggttc upstream-variant-2KB
rs2540411 -- 32,733,970(-) CAGAA(C/T)TGATG upstream-variant-2KB
rs2923268 -- 32,734,834(+) GTACA(C/T)AGTGA upstream-variant-2KB
rs10237436 -- 32,733,792(+) TATCA(A/G)AGGTG upstream-variant-2KB
rs113067996 -- 32,734,544(+) TTTGA(A/G)AGCAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR550B2 Gene

Variant ID Type Subtype PubMed ID
dgv1127e201 CNV Deletion 23290073
nsv830941 CNV Gain 17160897
nsv436907 CNV Insertion 17901297
esv29452 CNV Gain+Loss 19812545

Relevant External Links for MIR550B2 Gene

HapMap Linkage Disequilibrium report
MIR550B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR550B2 Gene

Disorders for MIR550B2 Gene

No disorders were found for MIR550B2 Gene.

No data available for UniProtKB/Swiss-Prot for MIR550B2 Gene

Publications for MIR550B2 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3

Products for MIR550B2 Gene

Sources for MIR550B2 Gene

Back to Top

Content