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Aliases for MIR550B1 Gene

Subcategory (RNA class) for MIR550B1 Gene


Quality Score for this RNA gene is


Aliases for MIR550B1 Gene

  • MicroRNA 550b-1 2 3
  • Hsa-Mir-550a-1 5
  • Hsa-Mir-550b-1 3

External Ids for MIR550B1 Gene

Previous GeneCards Identifiers for MIR550B1 Gene

  • GC07U903110

Summaries for MIR550B1 Gene

Entrez Gene Summary for MIR550B1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR550B1 Gene

MIR550B1 (MicroRNA 550b-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR550B1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR550B1 Gene

Genomics for MIR550B1 Gene

GeneHancer (GH) Regulatory Elements for MIR550B1 Gene

Promoters and enhancers for MIR550B1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I030289 Enhancer 1 Ensembl ENCODE 550.8 -0.5 -487 1.6 CTCF HDGF HDAC1 PKNOX1 SIN3A BATF ZNF507 ZNF335 GATA3 CBFA2T2 GC07P030289 MIR550A1 MIR550B1 DKFZP586I1420 ZNRF2 GC07P030343
GH07I030317 Enhancer 1 Ensembl ENCODE 0.3 -30.9 -30869 6.4 FEZF1 BATF IRF4 ZNF335 ATF7 RCOR1 FOS BCLAF1 RUNX3 ZBTB11 NOD1 GC07P030343 MIR550B1 ZNRF2
GH07I030329 Enhancer 1 Ensembl ENCODE 0.3 -40.8 -40755 2.1 PKNOX1 MZF1 BATF IRF4 ATF7 BCLAF1 IKZF2 RUNX3 SMARCA5 CBFB ENSG00000223813 ZNRF2 GC07P030343 MIR550B1
GH07I030310 Enhancer 0.5 ENCODE 0.3 -20.8 -20753 0.6 IKZF1 JUNB BATF IKZF2 MIR550A1 ZNRF2 MIR550B1 GC07P030343
GH07I030301 Enhancer 0.3 ENCODE 0.4 -12.0 -12030 0.2 ZNF362 NOD1 MIR550B1 ZNRF2 GC07P030343
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR550B1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR550B1 Gene

Genomic Locations for MIR550B1 Gene
97 bases
Minus strand

Genomic View for MIR550B1 Gene

Genes around MIR550B1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR550B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR550B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR550B1 Gene

Proteins for MIR550B1 Gene

Post-translational modifications for MIR550B1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR550B1 Gene

Domains & Families for MIR550B1 Gene

Gene Families for MIR550B1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR550B1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR550B1 Gene

Function for MIR550B1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR550B1 Gene

Localization for MIR550B1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR550B1 Gene

Pathways & Interactions for MIR550B1 Gene

SuperPathways for MIR550B1 Gene

No Data Available

Interacting Proteins for MIR550B1 Gene

Gene Ontology (GO) - Biological Process for MIR550B1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR550B1 Gene

Drugs & Compounds for MIR550B1 Gene

No Compound Related Data Available

Transcripts for MIR550B1 Gene

mRNA/cDNA for MIR550B1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR550B1 Gene

No ASD Table

Relevant External Links for MIR550B1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR550B1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR550B1 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR550B1 Gene

Orthologs for MIR550B1 Gene

Evolution for MIR550B1 Gene

Gene Tree for MIR550B1 (if available)
Gene Tree for MIR550B1 (if available)

No data available for Orthologs for MIR550B1 Gene

Paralogs for MIR550B1 Gene

No data available for Paralogs for MIR550B1 Gene

Variants for MIR550B1 Gene

Sequence variations from dbSNP and Humsavar for MIR550B1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000305971 -- 30,289,641(-) A/C downstream_transcript_variant
rs1000607538 -- 30,291,214(-) A/G upstream_transcript_variant
rs1000642001 -- 30,290,844(-) G/A upstream_transcript_variant
rs1002403456 -- 30,290,751(-) A/G upstream_transcript_variant
rs1002427975 -- 30,290,400(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR550B1 Gene

Variant ID Type Subtype PubMed ID
nsv1019527 CNV gain 25217958
nsv1068321 OTHER inversion 25765185
nsv1148830 OTHER inversion 26484159
nsv436557 CNV deletion 17901297
nsv981445 CNV duplication 23825009

Additional Variant Information for MIR550B1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR550B1 Gene

Disorders for MIR550B1 Gene

Additional Disease Information for MIR550B1

No disorders were found for MIR550B1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR550B1 Gene

Publications for MIR550B1 Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR550B1 Gene

Sources for MIR550B1 Gene

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